Campylobacter coli strains from Brazil can invade phagocytic and epithelial cells and induce IL-8 secretion

Detalhes bibliográficos
Autor(a) principal: Gomes, Carolina N.
Data de Publicação: 2021
Outros Autores: Campioni, Fábio, Vilela, Felipe P., Duque, Sheila S., Falcão, Juliana P.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/49854
Resumo: Universidade de São Paulo. Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Departamento de Análises Clínicas, Toxicológicas e Bromatológicas. Ribeirão Preto, SP, Brasil.
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spelling Gomes, Carolina N.Campioni, FábioVilela, Felipe P.Duque, Sheila S.Falcão, Juliana P.2021-11-17T13:05:32Z2021-11-17T13:05:32Z2021GOMES, Carolina N. et al. Campylobacter coli strains from Brazil can invade phagocytic and epithelial cells and induce IL-8 secretion. Brazilian Journal of Microbiology, v. 52, n. 2, p. 859-867, Feb, 2021.1678-4405https://www.arca.fiocruz.br/handle/icict/4985410.1007/s42770-021-00450-1engSociedade Brasileira de MicrobiologiaPatógenos de origem alimentarLinhas celulares Caco-2 e U-937CitocinasBrasilFoodborne pathogensCaco-2 and U-937 cell linesCytokinesBrazilCampylobacter coli strains from Brazil can invade phagocytic and epithelial cells and induce IL-8 secretioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade de São Paulo. Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Departamento de Análises Clínicas, Toxicológicas e Bromatológicas. Ribeirão Preto, SP, Brasil.Universidade de São Paulo. Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Departamento de Análises Clínicas, Toxicológicas e Bromatológicas. Ribeirão Preto, SP, Brasil.Universidade de São Paulo. Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Departamento de Análises Clínicas, Toxicológicas e Bromatológicas. Ribeirão Preto, SP, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Universidade de São Paulo. Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Departamento de Análises Clínicas, Toxicológicas e Bromatológicas. Ribeirão Preto, SP, Brasil.Campylobacter spp. have been a predominant cause of bacterial foodborne gastroenteritis worldwide, causing substantial costs to public healthcare systems. This study aimed to assess the invasion and pro-inflammatory cytokine production capacity of Campylobacter coli strains isolated in Brazil. A total of 50 C. coli isolated from different sources in Brazil were analyzed for their capacity of invasion in Caco-2 and U-937 cell lines. The production of pro-inflammatory cytokines was quantitatively measured in response to C. coli. All the strains studied showed invasion percentage ≥ 40% in polarized Caco-2 cells. In U-937 cells assay, 35 of 50 C. coli strains studied showed invasion percentage ≥ 50%. A significant increase in IL-8 production by infected U-937 cells was observed for 17.5% of the C. coli isolates. The high percentages of invasion in Caco-2 and U-937 cells observed for all studied strains, plus the increased production of IL-8 by U-937 cells against some strains, highlighted the pathogenic potential of the C. coli studied and bring extremely relevant data since it has never been reported for strains isolated in Brazil and there are a few data for C. coli in the literature.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/49854/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALSheila_Duque_etal_IOC_2021.pdfSheila_Duque_etal_IOC_2021.pdfapplication/pdf766363https://www.arca.fiocruz.br/bitstream/icict/49854/2/Sheila_Duque_etal_IOC_2021.pdff3b8811fc00f82c459d8943dcc7784e3MD52icict/498542021-11-17 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dc.title.pt_BR.fl_str_mv Campylobacter coli strains from Brazil can invade phagocytic and epithelial cells and induce IL-8 secretion
title Campylobacter coli strains from Brazil can invade phagocytic and epithelial cells and induce IL-8 secretion
spellingShingle Campylobacter coli strains from Brazil can invade phagocytic and epithelial cells and induce IL-8 secretion
Gomes, Carolina N.
Patógenos de origem alimentar
Linhas celulares Caco-2 e U-937
Citocinas
Brasil
Foodborne pathogens
Caco-2 and U-937 cell lines
Cytokines
Brazil
title_short Campylobacter coli strains from Brazil can invade phagocytic and epithelial cells and induce IL-8 secretion
title_full Campylobacter coli strains from Brazil can invade phagocytic and epithelial cells and induce IL-8 secretion
title_fullStr Campylobacter coli strains from Brazil can invade phagocytic and epithelial cells and induce IL-8 secretion
title_full_unstemmed Campylobacter coli strains from Brazil can invade phagocytic and epithelial cells and induce IL-8 secretion
title_sort Campylobacter coli strains from Brazil can invade phagocytic and epithelial cells and induce IL-8 secretion
author Gomes, Carolina N.
author_facet Gomes, Carolina N.
Campioni, Fábio
Vilela, Felipe P.
Duque, Sheila S.
Falcão, Juliana P.
author_role author
author2 Campioni, Fábio
Vilela, Felipe P.
Duque, Sheila S.
Falcão, Juliana P.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Gomes, Carolina N.
Campioni, Fábio
Vilela, Felipe P.
Duque, Sheila S.
Falcão, Juliana P.
dc.subject.other.pt_BR.fl_str_mv Patógenos de origem alimentar
Linhas celulares Caco-2 e U-937
Citocinas
Brasil
topic Patógenos de origem alimentar
Linhas celulares Caco-2 e U-937
Citocinas
Brasil
Foodborne pathogens
Caco-2 and U-937 cell lines
Cytokines
Brazil
dc.subject.en.pt_BR.fl_str_mv Foodborne pathogens
Caco-2 and U-937 cell lines
Cytokines
Brazil
description Universidade de São Paulo. Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Departamento de Análises Clínicas, Toxicológicas e Bromatológicas. Ribeirão Preto, SP, Brasil.
publishDate 2021
dc.date.accessioned.fl_str_mv 2021-11-17T13:05:32Z
dc.date.available.fl_str_mv 2021-11-17T13:05:32Z
dc.date.issued.fl_str_mv 2021
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv GOMES, Carolina N. et al. Campylobacter coli strains from Brazil can invade phagocytic and epithelial cells and induce IL-8 secretion. Brazilian Journal of Microbiology, v. 52, n. 2, p. 859-867, Feb, 2021.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/49854
dc.identifier.issn.pt_BR.fl_str_mv 1678-4405
dc.identifier.doi.none.fl_str_mv 10.1007/s42770-021-00450-1
identifier_str_mv GOMES, Carolina N. et al. Campylobacter coli strains from Brazil can invade phagocytic and epithelial cells and induce IL-8 secretion. Brazilian Journal of Microbiology, v. 52, n. 2, p. 859-867, Feb, 2021.
1678-4405
10.1007/s42770-021-00450-1
url https://www.arca.fiocruz.br/handle/icict/49854
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Sociedade Brasileira de Microbiologia
publisher.none.fl_str_mv Sociedade Brasileira de Microbiologia
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/49854/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/49854/2/Sheila_Duque_etal_IOC_2021.pdf
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
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