Proteomic analysis of Ascocotyle longa (Trematoda: Heterophyidae) metacercariae

Bibliographic Details
Main Author: Rebello, Karina M.
Publication Date: 2020
Other Authors: Borges, Juliana N., Teixeira, André, Perales, Jonas, Santos, Cláudia P.
Format: Article
Language: eng
Source: Repositório Institucional da FIOCRUZ (ARCA)
Download full: https://www.arca.fiocruz.br/handle/icict/43186
Summary: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Estudos Integrados em Protozoologia. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Toxinologia. Rio de Janeiro, RJ, Brasil.
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spelling Rebello, Karina M.Borges, Juliana N.Teixeira, AndréPerales, JonasSantos, Cláudia P.2020-09-04T18:44:57Z2020-09-04T18:44:57Z2020REBELLO, Karina M. et al. Proteomic analysis of Ascocotyle longa (Trematoda: Heterophyidae) metacercariae. Molecular & Biochemical Parasitology, v. 238, p. 1-10, Aug. 2020.0166-6851https://www.arca.fiocruz.br/handle/icict/4318610.1016/j.molbiopara.2020.111311engElsevierPatógeno nascido em peixeProteínasParasitaHelmintoMugil lizaFish-born pathogenProteinsParasiteHelminthHeterophyiasisProteomic analysis of Ascocotyle longa (Trematoda: Heterophyidae) metacercariaeinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Estudos Integrados em Protozoologia. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Toxinologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Avaliação e Promoção da Saúde Ambiental. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Toxinologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Toxinologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Avaliação e Promoção da Saúde Ambiental. Rio de Janeiro, RJ, Brasil.Ascocotyle longa is parasitic trematode with wide distribution throughout America, Europe, Africa, and Middle East. Despite the fact that this fish-borne pathogen has been considered an agent of human heterophyiasis in Brazil, the molecules involved in the host-parasite interaction remain unknown. The present study reports the proteome profile of A. longa metacercariae collected from the fish Mugil liza from Brazil. This infective stage for humans, mammals and birds was analyzed using nLC-MS/MS approach. We identified a large repertoire of proteins, which are mainly involved in energy metabolism and cell structure. Peptidases and immunogenic proteins were also identified, which might play roles in host-parasite interface. Our data provided unprecedented insights into the biology of A. longa and represent a first step to understand the natural host-parasite interaction. Moreover, as the first proteome characterized in this trematode, it will provide an important resource for future studies.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/43186/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALKarinaRabello_JonasPerales_etal_IOC_2020.pdfKarinaRabello_JonasPerales_etal_IOC_2020.pdfapplication/pdf1683082https://www.arca.fiocruz.br/bitstream/icict/43186/2/KarinaRabello_JonasPerales_etal_IOC_2020.pdf0e518c00bfd071dd9a96944cb4f9f634MD52TEXTKarinaRabello_JonasPerales_etal_IOC_2020.pdf.txtKarinaRabello_JonasPerales_etal_IOC_2020.pdf.txtExtracted texttext/plain63964https://www.arca.fiocruz.br/bitstream/icict/43186/3/KarinaRabello_JonasPerales_etal_IOC_2020.pdf.txtb129db58a5c432cb256a0e874f7f363bMD53icict/431862020-12-01 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dc.title.pt_BR.fl_str_mv Proteomic analysis of Ascocotyle longa (Trematoda: Heterophyidae) metacercariae
title Proteomic analysis of Ascocotyle longa (Trematoda: Heterophyidae) metacercariae
spellingShingle Proteomic analysis of Ascocotyle longa (Trematoda: Heterophyidae) metacercariae
Rebello, Karina M.
Patógeno nascido em peixe
Proteínas
Parasita
Helminto
Mugil liza
Fish-born pathogen
Proteins
Parasite
Helminth
Heterophyiasis
title_short Proteomic analysis of Ascocotyle longa (Trematoda: Heterophyidae) metacercariae
title_full Proteomic analysis of Ascocotyle longa (Trematoda: Heterophyidae) metacercariae
title_fullStr Proteomic analysis of Ascocotyle longa (Trematoda: Heterophyidae) metacercariae
title_full_unstemmed Proteomic analysis of Ascocotyle longa (Trematoda: Heterophyidae) metacercariae
title_sort Proteomic analysis of Ascocotyle longa (Trematoda: Heterophyidae) metacercariae
author Rebello, Karina M.
author_facet Rebello, Karina M.
Borges, Juliana N.
Teixeira, André
Perales, Jonas
Santos, Cláudia P.
author_role author
author2 Borges, Juliana N.
Teixeira, André
Perales, Jonas
Santos, Cláudia P.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Rebello, Karina M.
Borges, Juliana N.
Teixeira, André
Perales, Jonas
Santos, Cláudia P.
dc.subject.other.pt_BR.fl_str_mv Patógeno nascido em peixe
Proteínas
Parasita
Helminto
topic Patógeno nascido em peixe
Proteínas
Parasita
Helminto
Mugil liza
Fish-born pathogen
Proteins
Parasite
Helminth
Heterophyiasis
dc.subject.en.pt_BR.fl_str_mv Mugil liza
Fish-born pathogen
Proteins
Parasite
Helminth
Heterophyiasis
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Estudos Integrados em Protozoologia. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Toxinologia. Rio de Janeiro, RJ, Brasil.
publishDate 2020
dc.date.accessioned.fl_str_mv 2020-09-04T18:44:57Z
dc.date.available.fl_str_mv 2020-09-04T18:44:57Z
dc.date.issued.fl_str_mv 2020
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv REBELLO, Karina M. et al. Proteomic analysis of Ascocotyle longa (Trematoda: Heterophyidae) metacercariae. Molecular & Biochemical Parasitology, v. 238, p. 1-10, Aug. 2020.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/43186
dc.identifier.issn.pt_BR.fl_str_mv 0166-6851
dc.identifier.doi.pt_BR.fl_str_mv 10.1016/j.molbiopara.2020.111311
identifier_str_mv REBELLO, Karina M. et al. Proteomic analysis of Ascocotyle longa (Trematoda: Heterophyidae) metacercariae. Molecular & Biochemical Parasitology, v. 238, p. 1-10, Aug. 2020.
0166-6851
10.1016/j.molbiopara.2020.111311
url https://www.arca.fiocruz.br/handle/icict/43186
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/43186/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/43186/2/KarinaRabello_JonasPerales_etal_IOC_2020.pdf
https://www.arca.fiocruz.br/bitstream/icict/43186/3/KarinaRabello_JonasPerales_etal_IOC_2020.pdf.txt
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bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
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