Laminin-database v.2.0: an update on laminins in health and neuromuscular disorders

Detalhes bibliográficos
Autor(a) principal: Golbert, Daiane C. F
Data de Publicação: 2014
Outros Autores: van Vliet, Eliane Santana, Mundstein, Alex S, Calfo, Vicente, Savino, Wilson, Vasconcelos, Ana Tereza R. de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/10682
Resumo: Laboratório Nacional de Computação Científica. Laboratório de Bioinformática. Petrópolis, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ, Brasil.
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spelling Golbert, Daiane C. Fvan Vliet, Eliane SantanaMundstein, Alex SCalfo, VicenteSavino, WilsonVasconcelos, Ana Tereza R. de2015-06-08T14:01:48Z2015-06-08T14:01:48Z2014GOLBERT, Daiane C. F. et al. Laminin-database v.2.0: an update on laminins in health and neuromuscular disorders. Nucleic Acids Research, v.42, p.D426-D429, Jan. 2014.1362-4962https://www.arca.fiocruz.br/handle/icict/1068210.1093/nar/gkt901engOxford University PressLaminin-database v.2.0: an update on laminins in health and neuromuscular disordersinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleLaboratório Nacional de Computação Científica. Laboratório de Bioinformática. Petrópolis, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ, BrasilLaboratório Nacional de Computação Científica. Laboratório de Bioinformática. Petrópolis, RJ, Brasil.Laboratório Nacional de Computação Científica. Laboratório de Bioinformática. Petrópolis, RJ, BrasilFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ, BrasilLaboratório Nacional de Computação Científica. Laboratório de Bioinformática. Petrópolis, RJ, BrasilThe laminin (LM)-database, hosted at http://www. lm.lncc.br, was published in the NAR database 2011 edition. It was the first database that provided comprehensive information concerning a non-collagenous family of extracellular matrix proteins, the LMs. In its first version, this database contained a large amount of information concerning LMs related to health and disease, with particular emphasis on the haemopoietic system. Users can easily access several tabs for LMs and LM-related molecules, as well as LM nomenclatures and direct links to PubMed. The LM-database version 2.0 integrates data from several publications to achieve a more comprehensive knowledge of LMs in health and disease. The novel features include the addition of two new tabs, ‘Neuromuscular Disorders’ and ‘miRNA-–LM Relationship’. More specifically, in this updated version, an expanding set of data has been displayed concerning the role of LMs in neuromuscular and neurodegenerative diseases, as well as the putative involvement of microRNAs. Given the importance of LMs in several biological processes, such as cell adhesion, proliferation, differentiation, migration and cell death, this upgraded version expands for users a panoply of information, regarding complex molecular circuitries that involve LMs in health and disease, including neuromuscular and neurodegenerative disorders.Neuromuscular disordersLaminin-database v.2.0LamininaDoenças Neurodegenerativasinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1914https://www.arca.fiocruz.br/bitstream/icict/10682/1/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD51ORIGINALwilson_savinoetal_IOC_2014.pdfapplication/pdf86510https://www.arca.fiocruz.br/bitstream/icict/10682/2/wilson_savinoetal_IOC_2014.pdf5e7a51ac8d8e028f73f5e27a5fed276aMD52TEXTwilson_savinoetal_IOC_2014.pdf.txtwilson_savinoetal_IOC_2014.pdf.txtExtracted texttext/plain20143https://www.arca.fiocruz.br/bitstream/icict/10682/3/wilson_savinoetal_IOC_2014.pdf.txte314cab869e131371fa7a223802d2591MD53icict/106822022-06-24 12:18:53.692oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-06-24T15:18:53Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Laminin-database v.2.0: an update on laminins in health and neuromuscular disorders
title Laminin-database v.2.0: an update on laminins in health and neuromuscular disorders
spellingShingle Laminin-database v.2.0: an update on laminins in health and neuromuscular disorders
Golbert, Daiane C. F
Neuromuscular disorders
Laminin-database v.2.0
Laminina
Doenças Neurodegenerativas
title_short Laminin-database v.2.0: an update on laminins in health and neuromuscular disorders
title_full Laminin-database v.2.0: an update on laminins in health and neuromuscular disorders
title_fullStr Laminin-database v.2.0: an update on laminins in health and neuromuscular disorders
title_full_unstemmed Laminin-database v.2.0: an update on laminins in health and neuromuscular disorders
title_sort Laminin-database v.2.0: an update on laminins in health and neuromuscular disorders
author Golbert, Daiane C. F
author_facet Golbert, Daiane C. F
van Vliet, Eliane Santana
Mundstein, Alex S
Calfo, Vicente
Savino, Wilson
Vasconcelos, Ana Tereza R. de
author_role author
author2 van Vliet, Eliane Santana
Mundstein, Alex S
Calfo, Vicente
Savino, Wilson
Vasconcelos, Ana Tereza R. de
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Golbert, Daiane C. F
van Vliet, Eliane Santana
Mundstein, Alex S
Calfo, Vicente
Savino, Wilson
Vasconcelos, Ana Tereza R. de
dc.subject.en.pt_BR.fl_str_mv Neuromuscular disorders
Laminin-database v.2.0
topic Neuromuscular disorders
Laminin-database v.2.0
Laminina
Doenças Neurodegenerativas
dc.subject.decs.pt_BR.fl_str_mv Laminina
Doenças Neurodegenerativas
description Laboratório Nacional de Computação Científica. Laboratório de Bioinformática. Petrópolis, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ, Brasil.
publishDate 2014
dc.date.issued.fl_str_mv 2014
dc.date.accessioned.fl_str_mv 2015-06-08T14:01:48Z
dc.date.available.fl_str_mv 2015-06-08T14:01:48Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv GOLBERT, Daiane C. F. et al. Laminin-database v.2.0: an update on laminins in health and neuromuscular disorders. Nucleic Acids Research, v.42, p.D426-D429, Jan. 2014.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/10682
dc.identifier.issn.pt_BR.fl_str_mv 1362-4962
dc.identifier.doi.pt_BR.fl_str_mv 10.1093/nar/gkt901
identifier_str_mv GOLBERT, Daiane C. F. et al. Laminin-database v.2.0: an update on laminins in health and neuromuscular disorders. Nucleic Acids Research, v.42, p.D426-D429, Jan. 2014.
1362-4962
10.1093/nar/gkt901
url https://www.arca.fiocruz.br/handle/icict/10682
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Oxford University Press
publisher.none.fl_str_mv Oxford University Press
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
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