Clinical characteristics and outcomes among Brazilian patients with severe acute respiratory syndrome coronavirus 2 infection: an observational retrospective study

Detalhes bibliográficos
Autor(a) principal: Nascimento, Israel Júnior Borges do
Data de Publicação: 2020
Outros Autores: Pinto, Luiz Ricardo, Fernandes, Valéria Alves, Romero, Israel Molina, Oliveira, João Antonio de Queiroz, Marcolino, Milena Soriano, Leite, Maria Fátima
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/44726
Resumo: Universidade Federal de Minas Gerais. Clinical Pathologist and Medical Research Specialist. University Hospital and School of Medicine. Belo Horizonte, MG, Brazil / Medical Research Specialist. School of Medicine. Medical College of Wisconsin. Milwaukee, Wisconsin, USA.
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spelling Nascimento, Israel Júnior Borges doPinto, Luiz RicardoFernandes, Valéria AlvesRomero, Israel MolinaOliveira, João Antonio de QueirozMarcolino, Milena SorianoLeite, Maria Fátima2020-12-07T13:16:17Z2020-12-07T13:16:17Z2020NASCIMENTO, Israel Júnior Borges do et al. Clinical characteristics and outcomes among Brazilian patients with severe acute respiratory syndrome coronavirus 2 infection: an observational retrospective study. São Paulo Medical Journal, p. 1-8, 2020.1516-3180https://www.arca.fiocruz.br/handle/icict/4472610.1590/1516-3180.2020.00365.r1.08092020engAssociação Paulista de MedicinaClinical characteristics and outcomes among Brazilian patients with severe acute respiratory syndrome coronavirus 2 infection: an observational retrospective studyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal de Minas Gerais. Clinical Pathologist and Medical Research Specialist. University Hospital and School of Medicine. Belo Horizonte, MG, Brazil / Medical Research Specialist. School of Medicine. Medical College of Wisconsin. Milwaukee, Wisconsin, USA.Department of Production Engineering, School of Engineering, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.University Hospital and School of Medicine. Universidade Federal de Minas Gerais. Belo Horizonte, MG, Brazil.Department of Infectious Diseases. Vall d’Hebron Hospital. Barcelona, Spain / Oswaldo Cruz Foundation. Instituto Renê Rachou. Medical Researcher. Belo Horizonte, MG, Brazil.University Hospital and School of Medicin. Universidade Federal de Minas Gerais. Belo Horizonte, MG, Brazil.University Hospital and School of Medicine. Universidade Federal de Minas Gerais. Belo Horizonte, MG, Brazil.Department of Physiology and Biophysics. Institute of Biological Science. Universidade Federal de Minas Gerais. Belo Horizonte, MG, Brazil.BACKGROUND: Since February 2020, data on the clinical features of patients infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and their clinical evolution have been gathered and intensively discussed, especially in countries with dramatic dissemination of this disease. OBJECTIVE: To assess the clinical features of Brazilian patients with SARS-CoV-2 and analyze its local epidemiological features. DESIGN AND SETTING: Observational retrospective study conducted using data from an official electronic platform for recording confirmed SARS-CoV-2 cases. METHODS: We extracted data from patients based in the state of Pernambuco who were registered on the platform of the Center for Strategic Health Surveillance Information, between February 26 and May 25, 2020. Clinical signs/symptoms, case evolution over time, distribution of confirmed, recovered and fatal cases and relationship between age group and gender were assessed. RESULTS: We included 28,854 patients who were positive for SARS-CoV-2 (56.13% females), of median age 44.18 years. SARS-CoV-2 infection was most frequent among adults aged 30-39 years. Among cases that progressed to death, the most frequent age range was 70-79 years. Overall, the mortality rate in the cohort was 8.06%; recovery rate, 30.7%; and hospital admission rate (up to the end of follow-up), 17.3%. The average length of time between symptom onset and death was 10.3 days. The most commonly reported symptoms were coughing (42.39%), fever (38.03%) and dyspnea/respiratory distress with oxygen saturation < 95% (30.98%). CONCLUSION: Coughing, fever and dyspnea/respiratory distress with oxygen saturation < 95% were the commonest symptoms. The case-fatality rate was 8.06% and the hospitalization rate, 17.3%.SARS-CoV-2COVID-19Coronavirus infectionsMandatory reportingPublic reporting of healthcare dataInfectious diseasesNovel coronavirus2019-nCoV infections2019 novel coronavirus infectioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83082https://www.arca.fiocruz.br/bitstream/icict/44726/1/license.txt9193a7c197bc67acd023525e72a03240MD51ORIGINALNascimento_Israel Júnior_etal_IRR_2020_COVID-19.pdfNascimento_Israel Júnior_etal_IRR_2020_COVID-19.pdfapplication/pdf205502https://www.arca.fiocruz.br/bitstream/icict/44726/2/Nascimento_Israel%20J%c3%banior_etal_IRR_2020_COVID-19.pdfd6796cec02d9d58342f86af324a16c7cMD52TEXTNascimento_Israel Júnior_etal_IRR_2020_COVID-19.pdf.txtNascimento_Israel Júnior_etal_IRR_2020_COVID-19.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Clinical characteristics and outcomes among Brazilian patients with severe acute respiratory syndrome coronavirus 2 infection: an observational retrospective study
title Clinical characteristics and outcomes among Brazilian patients with severe acute respiratory syndrome coronavirus 2 infection: an observational retrospective study
spellingShingle Clinical characteristics and outcomes among Brazilian patients with severe acute respiratory syndrome coronavirus 2 infection: an observational retrospective study
Nascimento, Israel Júnior Borges do
SARS-CoV-2
COVID-19
Coronavirus infections
Mandatory reporting
Public reporting of healthcare data
Infectious diseases
Novel coronavirus
2019-nCoV infections
2019 novel coronavirus infection
title_short Clinical characteristics and outcomes among Brazilian patients with severe acute respiratory syndrome coronavirus 2 infection: an observational retrospective study
title_full Clinical characteristics and outcomes among Brazilian patients with severe acute respiratory syndrome coronavirus 2 infection: an observational retrospective study
title_fullStr Clinical characteristics and outcomes among Brazilian patients with severe acute respiratory syndrome coronavirus 2 infection: an observational retrospective study
title_full_unstemmed Clinical characteristics and outcomes among Brazilian patients with severe acute respiratory syndrome coronavirus 2 infection: an observational retrospective study
title_sort Clinical characteristics and outcomes among Brazilian patients with severe acute respiratory syndrome coronavirus 2 infection: an observational retrospective study
author Nascimento, Israel Júnior Borges do
author_facet Nascimento, Israel Júnior Borges do
Pinto, Luiz Ricardo
Fernandes, Valéria Alves
Romero, Israel Molina
Oliveira, João Antonio de Queiroz
Marcolino, Milena Soriano
Leite, Maria Fátima
author_role author
author2 Pinto, Luiz Ricardo
Fernandes, Valéria Alves
Romero, Israel Molina
Oliveira, João Antonio de Queiroz
Marcolino, Milena Soriano
Leite, Maria Fátima
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Nascimento, Israel Júnior Borges do
Pinto, Luiz Ricardo
Fernandes, Valéria Alves
Romero, Israel Molina
Oliveira, João Antonio de Queiroz
Marcolino, Milena Soriano
Leite, Maria Fátima
dc.subject.en.pt_BR.fl_str_mv SARS-CoV-2
COVID-19
Coronavirus infections
Mandatory reporting
Public reporting of healthcare data
Infectious diseases
Novel coronavirus
2019-nCoV infections
2019 novel coronavirus infection
topic SARS-CoV-2
COVID-19
Coronavirus infections
Mandatory reporting
Public reporting of healthcare data
Infectious diseases
Novel coronavirus
2019-nCoV infections
2019 novel coronavirus infection
description Universidade Federal de Minas Gerais. Clinical Pathologist and Medical Research Specialist. University Hospital and School of Medicine. Belo Horizonte, MG, Brazil / Medical Research Specialist. School of Medicine. Medical College of Wisconsin. Milwaukee, Wisconsin, USA.
publishDate 2020
dc.date.accessioned.fl_str_mv 2020-12-07T13:16:17Z
dc.date.available.fl_str_mv 2020-12-07T13:16:17Z
dc.date.issued.fl_str_mv 2020
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv NASCIMENTO, Israel Júnior Borges do et al. Clinical characteristics and outcomes among Brazilian patients with severe acute respiratory syndrome coronavirus 2 infection: an observational retrospective study. São Paulo Medical Journal, p. 1-8, 2020.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/44726
dc.identifier.issn.pt_BR.fl_str_mv 1516-3180
dc.identifier.doi.none.fl_str_mv 10.1590/1516-3180.2020.00365.r1.08092020
identifier_str_mv NASCIMENTO, Israel Júnior Borges do et al. Clinical characteristics and outcomes among Brazilian patients with severe acute respiratory syndrome coronavirus 2 infection: an observational retrospective study. São Paulo Medical Journal, p. 1-8, 2020.
1516-3180
10.1590/1516-3180.2020.00365.r1.08092020
url https://www.arca.fiocruz.br/handle/icict/44726
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Associação Paulista de Medicina
publisher.none.fl_str_mv Associação Paulista de Medicina
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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