Temporal changes in causes of death among HIV-infected patients in the HAART era in Rio de Janeiro, Brazil
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2009 |
| Outros Autores: | , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/38971 |
Resumo: | Estevão P. Nunes. Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento. |
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Pacheco, Antonio G.Tuboi, Suely H.May, Silvia B.Moreira, Luiz F. S.Ramadas, LucianaNunes, Estevão P.Merçon, MônicaFaulhaber, José C.Harrison, Lee H.Schechter, M.2020-01-03T15:34:14Z2020-01-03T15:34:14Z2009PACHECO, Antonio G. et al. Temporal changes in causes of death among HIV-infected patients in the HAART era in Rio de Janeiro, Brazil. Journal of Acquired Immune Deficiency Syndromes, v. 51, n. 5, p. 624-630, Aug. 2009.1525-4135https://www.arca.fiocruz.br/handle/icict/3897110.1097/QAI.0b013e3181a4ecf51944-7884Estevão P. Nunes. Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento.2021-01-03Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Departamento de Epidemiologia e Métodos Quantitativos em Saúde. Rio de Janeiro, RJ, Brasil / University of Pittsburgh. Graduate School of Public Health and School of Medicine. Infectious Diseases Epidemiology Research Unit. Pittsburgh, PA, USA.University of Pittsburgh. Graduate School of Public Health and School of Medicine. Infectious Diseases Epidemiology Research Unit. Pittsburgh, PA, USA / Universidade Federal do Rio de Janeiro. Hospital Escola São Francisco de Assis. Projeto Praça Onze. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Hospital Universitário Clementino Fraga Filho. Serviço de Doenças Infecciosas e Parasitárias. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Hospital Universitário Clementino Fraga Filho. Serviço de Doenças Infecciosas e Parasitárias. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Hospital Universitário Clementino Fraga Filho. Serviço de Doenças Infecciosas e Parasitárias. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Hospital Escola São Francisco de Assis. Projeto Praça Onze. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Hospital Escola São Francisco de Assis. Projeto Praça Onze. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Hospital Escola São Francisco de Assis. Projeto Praça Onze. Rio de Janeiro, RJ, Brasil.University of Pittsburgh. Graduate School of Public Health and School of Medicine. Infectious Diseases Epidemiology Research Unit. Pittsburgh, PA, USA.Universidade Federal do Rio de Janeiro. Hospital Escola São Francisco de Assis. Projeto Praça Onze. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Hospital Universitário Clementino Fraga Filho. AIDS Research Laboratory. Rio de Janeiro, RJ, Brazil.Background: The widespread use of HAART has led to marked decreases in death rates in Brazil in HIV-infected individuals. Nonetheless, there are scarce data on specific causes of death. Methods: Death rates from a cohort of HIV-infected patients in Rio de Janeiro, Brazil were analyzed in two-year periods, from 1997 to 2006. Poisson models and survival models accounting for competing risks were used to assess association of co-variables. A standardized, validated algorithm was used to ascertain specific causes of death. Results: Of the 1,538 eligible patients, 226 (14.7%) died during the study period, corresponding to a mortality rate of 3.2/100 person-years. The median follow-up time was 4.61 years (IQR = 5.63 years) and the loss to follow-up rate was 2.4/100 person-years. Overall, 98 (43.4%) were classified as non-AIDS-related causes. Although opportunistic infections were the leading causes of death (37.6%), deaths due to AIDS-related causes declined significantly over time (p<0.01). In the most recent period (2005-2006) the rate of non-AIDS related causes of deaths was higher than that of AIDS-related causes of death. Conclusions: In the HAART era there has been a significant change in causes of death among HIV-infected patients in Rio de Janeiro. As access to HAART improves, integration with other public programs will become critically important for the long term success of HIV/AIDS programs in developing countries.engInstituto Oswaldo Cruz, Ministério da SaúdeTemporal changes in causes of death among HIV-infected patients in the HAART era in Rio de Janeiro, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleHIVAIDSBrazilCauses of deathinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/38971/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALva_Pacheco_Antonio_etal_INI_2009.pdfva_Pacheco_Antonio_etal_INI_2009.pdfapplication/pdf376365https://www.arca.fiocruz.br/bitstream/icict/38971/2/va_Pacheco_Antonio_etal_INI_2009.pdf9d227cc1066f3330c9e5f0288301039aMD52TEXTva_Pacheco_Antonio_etal_INI_2009.pdf.txtva_Pacheco_Antonio_etal_INI_2009.pdf.txtExtracted texttext/plain36423https://www.arca.fiocruz.br/bitstream/icict/38971/3/va_Pacheco_Antonio_etal_INI_2009.pdf.txt9e5f4119955e372f3c9f04c61fa2b49cMD53icict/389712021-03-24 16:32:42.089oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352021-03-24T19:32:42Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
| dc.title.pt_BR.fl_str_mv |
Temporal changes in causes of death among HIV-infected patients in the HAART era in Rio de Janeiro, Brazil |
| title |
Temporal changes in causes of death among HIV-infected patients in the HAART era in Rio de Janeiro, Brazil |
| spellingShingle |
Temporal changes in causes of death among HIV-infected patients in the HAART era in Rio de Janeiro, Brazil Pacheco, Antonio G. HIV AIDS Brazil Causes of death |
| title_short |
Temporal changes in causes of death among HIV-infected patients in the HAART era in Rio de Janeiro, Brazil |
| title_full |
Temporal changes in causes of death among HIV-infected patients in the HAART era in Rio de Janeiro, Brazil |
| title_fullStr |
Temporal changes in causes of death among HIV-infected patients in the HAART era in Rio de Janeiro, Brazil |
| title_full_unstemmed |
Temporal changes in causes of death among HIV-infected patients in the HAART era in Rio de Janeiro, Brazil |
| title_sort |
Temporal changes in causes of death among HIV-infected patients in the HAART era in Rio de Janeiro, Brazil |
| author |
Pacheco, Antonio G. |
| author_facet |
Pacheco, Antonio G. Tuboi, Suely H. May, Silvia B. Moreira, Luiz F. S. Ramadas, Luciana Nunes, Estevão P. Merçon, Mônica Faulhaber, José C. Harrison, Lee H. Schechter, M. |
| author_role |
author |
| author2 |
Tuboi, Suely H. May, Silvia B. Moreira, Luiz F. S. Ramadas, Luciana Nunes, Estevão P. Merçon, Mônica Faulhaber, José C. Harrison, Lee H. Schechter, M. |
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author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Pacheco, Antonio G. Tuboi, Suely H. May, Silvia B. Moreira, Luiz F. S. Ramadas, Luciana Nunes, Estevão P. Merçon, Mônica Faulhaber, José C. Harrison, Lee H. Schechter, M. |
| dc.subject.en.pt_BR.fl_str_mv |
HIV AIDS Brazil Causes of death |
| topic |
HIV AIDS Brazil Causes of death |
| description |
Estevão P. Nunes. Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento. |
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2009 |
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2009 |
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2020-01-03T15:34:14Z |
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2020-01-03T15:34:14Z |
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PACHECO, Antonio G. et al. Temporal changes in causes of death among HIV-infected patients in the HAART era in Rio de Janeiro, Brazil. Journal of Acquired Immune Deficiency Syndromes, v. 51, n. 5, p. 624-630, Aug. 2009. |
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10.1097/QAI.0b013e3181a4ecf5 |
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1944-7884 |
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PACHECO, Antonio G. et al. Temporal changes in causes of death among HIV-infected patients in the HAART era in Rio de Janeiro, Brazil. Journal of Acquired Immune Deficiency Syndromes, v. 51, n. 5, p. 624-630, Aug. 2009. 1525-4135 10.1097/QAI.0b013e3181a4ecf5 1944-7884 |
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