Fractional Laser Resurfacing Treats Photoaging by Promoting Neocollegenesis and Cutaneous Edema

Detalhes bibliográficos
Autor(a) principal: Borges, Juliano
Data de Publicação: 2020
Outros Autores: Araújo, Luciana, Cuzzi, Tullia, Martinez, Luis, Gonzales, Yliana, Manela-Azulay, Mônica
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/43962
Resumo: Universidade Federal do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.
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spelling Borges, JulianoAraújo, LucianaCuzzi, TulliaMartinez, LuisGonzales, YlianaManela-Azulay, Mônica2020-10-13T14:04:20Z2020-10-13T14:04:20Z2020BORGES, Juliano et al. Fractional Laser Resurfacing Treats Photoaging by Promoting Neocollegenesis and Cutaneous Edema. The Journal of Clinical and Aesthetic Dermatology, v. 13, n. 1, p. 22-27, 2020.1941-2789PMID: 32082467https://www.arca.fiocruz.br/handle/icict/43962engMatrix Medical CommunicationsFractional Laser Resurfacing Treats Photoaging by Promoting Neocollegenesis and Cutaneous Edemainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.Universidade Federal do Estado do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.Santa Casa de Misericórdia do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.Santa Casa de Misericórdia do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.BACKGROUND: Laser resurfacing is a common treatment for photoaging. This treatment creates skin incisions that initiate the wound healing cascade, including reorganization of the collagen matrix, in a dermal remodeling process that can last up to 12 months. OBJECTIVE: We compared the effects of nonablative and ablative Erbium fractional laser resurfacing on dermal content and arrangement of Collagen Types I and III, and on fibroblast activation. METHODS: Ten female patients (50-63 years) with Fitzpatrick Skin Types I-IV and clinical signs of photoaging underwent two types of Erbium fractional laser resurfacing (nonablative, 1540nm; ablative, 2940nm) on opposite sides of the face. Skin biopsies were obtained pretreatment and three months post-treatment. Morphometric analysis was performed using Picrosirius staining for overall collagen, and immunohistochemistry for Collagen Types I and III. Finally, hematoxylin and eosin staining was used to identify fibroblast activation. RESULTS: Both laser treatments induced reorganization of Collagen Types I and III and demonstrated signs of fibroblast activation. However, morphometric analysis of Picrosirius staining revealed that, after both treatments, there was a lower density of collagen fibers, which is characteristic of edema. CONCLUSION: At three months after laser resurfacing, skin lifting in photoaged skin likely resulted from new collagen deposition but also from edema.Collagen Type ICollagen Type IIIErbium fractional laser resurfacingAblativeAging skinNonablativePhotoagingRejuvenationSolar elastosisinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/43962/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALjuliano_borges_et_all.pdfapplication/pdf538874https://www.arca.fiocruz.br/bitstream/icict/43962/2/juliano_borges_et_all.pdfbc270846079d520c3fc80fd7bd6451a9MD52TEXTjuliano_borges_et_all.pdf.txtjuliano_borges_et_all.pdf.txtExtracted texttext/plain27943https://www.arca.fiocruz.br/bitstream/icict/43962/3/juliano_borges_et_all.pdf.txtb13b12c4e755755173ae35116e0cbec2MD53icict/439622020-10-14 02:04:45.069oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352020-10-14T05:04:45Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Fractional Laser Resurfacing Treats Photoaging by Promoting Neocollegenesis and Cutaneous Edema
title Fractional Laser Resurfacing Treats Photoaging by Promoting Neocollegenesis and Cutaneous Edema
spellingShingle Fractional Laser Resurfacing Treats Photoaging by Promoting Neocollegenesis and Cutaneous Edema
Borges, Juliano
Collagen Type I
Collagen Type III
Erbium fractional laser resurfacing
Ablative
Aging skin
Nonablative
Photoaging
Rejuvenation
Solar elastosis
title_short Fractional Laser Resurfacing Treats Photoaging by Promoting Neocollegenesis and Cutaneous Edema
title_full Fractional Laser Resurfacing Treats Photoaging by Promoting Neocollegenesis and Cutaneous Edema
title_fullStr Fractional Laser Resurfacing Treats Photoaging by Promoting Neocollegenesis and Cutaneous Edema
title_full_unstemmed Fractional Laser Resurfacing Treats Photoaging by Promoting Neocollegenesis and Cutaneous Edema
title_sort Fractional Laser Resurfacing Treats Photoaging by Promoting Neocollegenesis and Cutaneous Edema
author Borges, Juliano
author_facet Borges, Juliano
Araújo, Luciana
Cuzzi, Tullia
Martinez, Luis
Gonzales, Yliana
Manela-Azulay, Mônica
author_role author
author2 Araújo, Luciana
Cuzzi, Tullia
Martinez, Luis
Gonzales, Yliana
Manela-Azulay, Mônica
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Borges, Juliano
Araújo, Luciana
Cuzzi, Tullia
Martinez, Luis
Gonzales, Yliana
Manela-Azulay, Mônica
dc.subject.en.pt_BR.fl_str_mv Collagen Type I
Collagen Type III
Erbium fractional laser resurfacing
Ablative
Aging skin
Nonablative
Photoaging
Rejuvenation
Solar elastosis
topic Collagen Type I
Collagen Type III
Erbium fractional laser resurfacing
Ablative
Aging skin
Nonablative
Photoaging
Rejuvenation
Solar elastosis
description Universidade Federal do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.
publishDate 2020
dc.date.accessioned.fl_str_mv 2020-10-13T14:04:20Z
dc.date.available.fl_str_mv 2020-10-13T14:04:20Z
dc.date.issued.fl_str_mv 2020
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv BORGES, Juliano et al. Fractional Laser Resurfacing Treats Photoaging by Promoting Neocollegenesis and Cutaneous Edema. The Journal of Clinical and Aesthetic Dermatology, v. 13, n. 1, p. 22-27, 2020.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/43962
dc.identifier.issn.pt_BR.fl_str_mv 1941-2789
dc.identifier.other.none.fl_str_mv PMID: 32082467
identifier_str_mv BORGES, Juliano et al. Fractional Laser Resurfacing Treats Photoaging by Promoting Neocollegenesis and Cutaneous Edema. The Journal of Clinical and Aesthetic Dermatology, v. 13, n. 1, p. 22-27, 2020.
1941-2789
PMID: 32082467
url https://www.arca.fiocruz.br/handle/icict/43962
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Matrix Medical Communications
publisher.none.fl_str_mv Matrix Medical Communications
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
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