β3-adrenergic receptor polymorphism is related to cardiometabolic risk factors in obese Brazilian subjects

Detalhes bibliográficos
Autor(a) principal: Genelhu, V. A
Data de Publicação: 2010
Outros Autores: Francischetti, E. A., Duarte, S. F. P., Celoria, B. M. J., Oliveira, R. C., Cabello, P. H., Pimentel, M. M. G.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/22912
Resumo: Universidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Laboratório de Fisiopatologia Clínica e Experimental. Rio de Janeiro, RJ, Brasil.
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spelling Genelhu, V. AFrancischetti, E. A.Duarte, S. F. P.Celoria, B. M. J.Oliveira, R. C.Cabello, P. H.Pimentel, M. M. G.2017-10-24T10:24:32Z2017-10-24T10:24:32Z2010GENELHU, V. A. et al. β3-adrenergic receptor polymorphism is related to cardiometabolic risk factors in obese Brazilian subjects. Genetics and Molecular Research, v.9, n.3, p.1392-1397, 2010.1676-5680https://www.arca.fiocruz.br/handle/icict/22912engReceptores AdrenérgicosObesidadePolimorfismoAdiponectinaFator de risco cardiometabólicoAdrenergic receptorObesityPolymorphismsAdiponectinCardiometabolic risk factorβ3-adrenergic receptor polymorphism is related to cardiometabolic risk factors in obese Brazilian subjectsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Laboratório de Fisiopatologia Clínica e Experimental. Rio de Janeiro, RJ, Brasil.Universidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Laboratório de Fisiopatologia Clínica e Experimental. Rio de Janeiro, RJ, Brasil.Universidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Laboratório de Fisiopatologia Clínica e Experimental. Rio de Janeiro, RJ, Brasil.Universidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Laboratório de Fisiopatologia Clínica e Experimental. Rio de Janeiro, RJ, Brasil.Universidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Laboratório de Fisiopatologia Clínica e Experimental. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Humana. Rio de Janeiro, RJ. Brasil.Universidade do Estado do Rio de Janeiro. Instituto de Biologia Roberto Alcântara Gomes. Departamento de Genética. Serviço de Genética Humana. Rio de Janeiro, RJ, Brasil.We determined whether ADRβ3 polymorphism is associated with obesity-related traits in 140 obese patients. Molecular analysis was performed by PCR and RFLP. Individuals carrying the Arg64 allele had a lower waist-to-hip ratio, higher adiponectin and high-density lipoprotein cholesterol levels, and a tendency towards lower blood pressure. In contrast, Trp64/Trp64 carriers were at greater risk for dysmetabolic phenotypes (odds ratio = 2.88, P = 0.03).info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/22912/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALph_cabello_etal_IOC_2010.pdfph_cabello_etal_IOC_2010.pdfapplication/pdf208471https://www.arca.fiocruz.br/bitstream/icict/22912/2/ph_cabello_etal_IOC_2010.pdfabe6e8f78277681d0a1d4224329c8f52MD52TEXTph_cabello_etal_IOC_2010.pdf.txtph_cabello_etal_IOC_2010.pdf.txtExtracted texttext/plain17262https://www.arca.fiocruz.br/bitstream/icict/22912/3/ph_cabello_etal_IOC_2010.pdf.txt0a1f29756931fec9d0c788c14313079dMD53icict/229122018-08-15 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dc.title.pt_BR.fl_str_mv β3-adrenergic receptor polymorphism is related to cardiometabolic risk factors in obese Brazilian subjects
title β3-adrenergic receptor polymorphism is related to cardiometabolic risk factors in obese Brazilian subjects
spellingShingle β3-adrenergic receptor polymorphism is related to cardiometabolic risk factors in obese Brazilian subjects
Genelhu, V. A
Receptores Adrenérgicos
Obesidade
Polimorfismo
Adiponectina
Fator de risco cardiometabólico
Adrenergic receptor
Obesity
Polymorphisms
Adiponectin
Cardiometabolic risk factor
title_short β3-adrenergic receptor polymorphism is related to cardiometabolic risk factors in obese Brazilian subjects
title_full β3-adrenergic receptor polymorphism is related to cardiometabolic risk factors in obese Brazilian subjects
title_fullStr β3-adrenergic receptor polymorphism is related to cardiometabolic risk factors in obese Brazilian subjects
title_full_unstemmed β3-adrenergic receptor polymorphism is related to cardiometabolic risk factors in obese Brazilian subjects
title_sort β3-adrenergic receptor polymorphism is related to cardiometabolic risk factors in obese Brazilian subjects
author Genelhu, V. A
author_facet Genelhu, V. A
Francischetti, E. A.
Duarte, S. F. P.
Celoria, B. M. J.
Oliveira, R. C.
Cabello, P. H.
Pimentel, M. M. G.
author_role author
author2 Francischetti, E. A.
Duarte, S. F. P.
Celoria, B. M. J.
Oliveira, R. C.
Cabello, P. H.
Pimentel, M. M. G.
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Genelhu, V. A
Francischetti, E. A.
Duarte, S. F. P.
Celoria, B. M. J.
Oliveira, R. C.
Cabello, P. H.
Pimentel, M. M. G.
dc.subject.other.pt_BR.fl_str_mv Receptores Adrenérgicos
Obesidade
Polimorfismo
Adiponectina
Fator de risco cardiometabólico
topic Receptores Adrenérgicos
Obesidade
Polimorfismo
Adiponectina
Fator de risco cardiometabólico
Adrenergic receptor
Obesity
Polymorphisms
Adiponectin
Cardiometabolic risk factor
dc.subject.en.pt_BR.fl_str_mv Adrenergic receptor
Obesity
Polymorphisms
Adiponectin
Cardiometabolic risk factor
description Universidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Laboratório de Fisiopatologia Clínica e Experimental. Rio de Janeiro, RJ, Brasil.
publishDate 2010
dc.date.issued.fl_str_mv 2010
dc.date.accessioned.fl_str_mv 2017-10-24T10:24:32Z
dc.date.available.fl_str_mv 2017-10-24T10:24:32Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv GENELHU, V. A. et al. β3-adrenergic receptor polymorphism is related to cardiometabolic risk factors in obese Brazilian subjects. Genetics and Molecular Research, v.9, n.3, p.1392-1397, 2010.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/22912
dc.identifier.issn.pt_BR.fl_str_mv 1676-5680
identifier_str_mv GENELHU, V. A. et al. β3-adrenergic receptor polymorphism is related to cardiometabolic risk factors in obese Brazilian subjects. Genetics and Molecular Research, v.9, n.3, p.1392-1397, 2010.
1676-5680
url https://www.arca.fiocruz.br/handle/icict/22912
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
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reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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