Higher incidence of Zika in adult women than adult men in Rio de Janeiro suggests a significant contribution of sexual transmission from men to women
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2016 |
| Outros Autores: | , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | por |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/16378 |
Resumo: | Fundação Getúlio Vargas. Rio de Janeiro, RJ, Brasil. |
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Coelho, Flavio CodeçoDurovni, BetinaSaraceni, ValeriaLemos, CristinaCodeco, Claudia TorresCamargo, SabrinaCarvalho, Luiz Max deBastos, LeonardoArduini, DeniseVillela, Daniel A MArmstrong, Margaret2016-11-30T12:44:38Z2016-11-30T12:44:38Z2016COELHO, Flavio Codeço et al. Higher incidence of Zika in adult women than adult men in Rio de Janeiro suggests a significant contribution of sexual transmission from men to women. International Journal of Infectious Diseases, v.51, p. 128–132, 2016.1201-9712https://www.arca.fiocruz.br/handle/icict/1637810.1016/j.ijid.2016.08.023porElsevierHigher incidence of Zika in adult women than adult men in Rio de Janeiro suggests a significant contribution of sexual transmission from men to womeninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Getúlio Vargas. Rio de Janeiro, RJ, Brasil.Prefeitura do Rio de Janeiro. Secretaria Municipal de Saúde. Rio de Janeiro, RJ, Brasil.Prefeitura do Rio de Janeiro. Secretaria Municipal de Saúde. Rio de Janeiro, RJ, Brasil.Prefeitura do Rio de Janeiro. Secretaria Municipal de Saúde. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Presidência. Programa de Computação Científica. Rio de Janeiro, RJ, Brasil.Fundação Getúlio Vargas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Presidência. Programa de Computação Científica. Rio de Janeiro, RJ, Brasil.Fundação Getúlio Vargas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Presidência. Programa de Computação Científica. Rio de Janeiro, RJ, Brasil / University of Edinburgh. Institute of Evolutionary Biology, Edinburgh, UK.Fundação Oswaldo Cruz. Presidência. Programa de Computação Científica. Rio de Janeiro, RJ, Brasil.Prefeitura do Rio de Janeiro. Secretaria Municipal de Saúde. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Presidência. Programa de Computação Científica. Rio de Janeiro, RJ, Brasil.Fundação Getúlio Vargas. Rio de Janeiro, RJ, Brasil / MINES Paristech. PSL Research University. CERNA Centre for Industrial Economy. Paris, France.The recent emergence of Zika in Brazil and its association with an increased rate of congenital malformations has raised concerns over its impact on the birth rate in the country. Using data on the incidence of Zika in 2015-2016 and dengue in 2013 and 2015-2016 for the city of Rio de Janeiro (population 6.4 million), a massive increase of Zika in women compared to men was documented.Objectives: The recent emergence of Zika in Brazil and its association with an increased rate of congenital malformations has raised concerns over its impact on the birth rate in the country. Using data on the incidence of Zika in 2015–2016 and dengue in 2013 and 2015–2016 for the city of Rio de Janeiro (population 6.4 million), a massive increase of Zika in women compared to men was documented. Methods: The age-adjusted incidence was compared between men and women. A negative binomial Poisson generalized linear model was fitted to the Zika incidence data to determine the significance of sexual transmission statistically. Results: Even after correcting for the bias due to the systematic testing of pregnant women for Zika, there were found to be 90% more registered cases per 100 000 women than men in the sexually active age group (15–65 years); this was not the case for age groups <15 years and >65 years. Assuming that infected men transmit the disease to women in their semen, but that the converse is not true, some extra incidence in women is to be expected. An alternate hypothesis would be that women visit doctors more often than men. To test this, the incidence of dengue fever was compared in men and women in 2015 and in 2013 (before Zika reached Rio de Janeiro): in both years, women were 30% more likely to be reported with dengue. Conclusion: Women in the sexually active age group are far more likely to get Zika than men (+90% increase); sexual transmission is the most probable cause. Women in the 15–65 years age group are also 30% more likely to be reported with dengue than men, which is probably due to women being more careful with their health.ZikaSexual transmissionDengueAge-adjusted incidenceZika virusDengueinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALva_Flavio_Coelho_etal_Presidencia_2016.pdfva_Flavio_Coelho_etal_Presidencia_2016.pdfapplication/pdf1480880https://www.arca.fiocruz.br/bitstream/icict/16378/2/va_Flavio_Coelho_etal_Presidencia_2016.pdf04ec4b8aeec2a13453bf8bcfbaf57da6MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/16378/3/license.txt5a560609d32a3863062d77ff32785d58MD53TEXTva_Flavio_Coelho_etal_Presidencia_2016.pdf.txtva_Flavio_Coelho_etal_Presidencia_2016.pdf.txtExtracted 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| dc.title.pt_BR.fl_str_mv |
Higher incidence of Zika in adult women than adult men in Rio de Janeiro suggests a significant contribution of sexual transmission from men to women |
| title |
Higher incidence of Zika in adult women than adult men in Rio de Janeiro suggests a significant contribution of sexual transmission from men to women |
| spellingShingle |
Higher incidence of Zika in adult women than adult men in Rio de Janeiro suggests a significant contribution of sexual transmission from men to women Coelho, Flavio Codeço Zika Sexual transmission Dengue Age-adjusted incidence Zika virus Dengue |
| title_short |
Higher incidence of Zika in adult women than adult men in Rio de Janeiro suggests a significant contribution of sexual transmission from men to women |
| title_full |
Higher incidence of Zika in adult women than adult men in Rio de Janeiro suggests a significant contribution of sexual transmission from men to women |
| title_fullStr |
Higher incidence of Zika in adult women than adult men in Rio de Janeiro suggests a significant contribution of sexual transmission from men to women |
| title_full_unstemmed |
Higher incidence of Zika in adult women than adult men in Rio de Janeiro suggests a significant contribution of sexual transmission from men to women |
| title_sort |
Higher incidence of Zika in adult women than adult men in Rio de Janeiro suggests a significant contribution of sexual transmission from men to women |
| author |
Coelho, Flavio Codeço |
| author_facet |
Coelho, Flavio Codeço Durovni, Betina Saraceni, Valeria Lemos, Cristina Codeco, Claudia Torres Camargo, Sabrina Carvalho, Luiz Max de Bastos, Leonardo Arduini, Denise Villela, Daniel A M Armstrong, Margaret |
| author_role |
author |
| author2 |
Durovni, Betina Saraceni, Valeria Lemos, Cristina Codeco, Claudia Torres Camargo, Sabrina Carvalho, Luiz Max de Bastos, Leonardo Arduini, Denise Villela, Daniel A M Armstrong, Margaret |
| author2_role |
author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Coelho, Flavio Codeço Durovni, Betina Saraceni, Valeria Lemos, Cristina Codeco, Claudia Torres Camargo, Sabrina Carvalho, Luiz Max de Bastos, Leonardo Arduini, Denise Villela, Daniel A M Armstrong, Margaret |
| dc.subject.en.en.fl_str_mv |
Zika Sexual transmission Dengue Age-adjusted incidence |
| topic |
Zika Sexual transmission Dengue Age-adjusted incidence Zika virus Dengue |
| dc.subject.decs.pt_BR.fl_str_mv |
Zika virus Dengue |
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Fundação Getúlio Vargas. Rio de Janeiro, RJ, Brasil. |
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2016 |
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2016-11-30T12:44:38Z |
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2016-11-30T12:44:38Z |
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2016 |
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COELHO, Flavio Codeço et al. Higher incidence of Zika in adult women than adult men in Rio de Janeiro suggests a significant contribution of sexual transmission from men to women. International Journal of Infectious Diseases, v.51, p. 128–132, 2016. |
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https://www.arca.fiocruz.br/handle/icict/16378 |
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1201-9712 |
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10.1016/j.ijid.2016.08.023 |
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COELHO, Flavio Codeço et al. Higher incidence of Zika in adult women than adult men in Rio de Janeiro suggests a significant contribution of sexual transmission from men to women. International Journal of Infectious Diseases, v.51, p. 128–132, 2016. 1201-9712 10.1016/j.ijid.2016.08.023 |
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