High accuracy of an ELISA test based in a flagella antigen of Leishmania in serodiagnosis of canine visceral leishmaniasis with potential to improve the control measures in Brazil - A Phase II study

Detalhes bibliográficos
Autor(a) principal: Borja, Lairton Souza
Data de Publicação: 2018
Outros Autores: Coelho, Lívia Brito, Jesus, Matheus Silva de, Queiroz, Artur Trancoso Lopo de, Celedon, Paola Alejandra Fiorani, Zachin, Nilson Ivo Tonin, Silva, Edimilson Domingos, Ferreira, Antônio Gomes Pinto, Krieger, Marco Aurélio, Veras, Patrícia Sampaio Tavares, Fraga, Deborah Bittencourt Mothé
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/30578
Resumo: Instituto de Ciência e Tecnologia em Doenc¸as Tropicais (INCT-DT- Grant number: 576269/2008) and Fundac¸ão de Amparo a Pesquisa da Bahia (FAPESB – Grant number: JCB0010/2013).
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spelling Borja, Lairton SouzaCoelho, Lívia BritoJesus, Matheus Silva deQueiroz, Artur Trancoso Lopo deCeledon, Paola Alejandra FioraniZachin, Nilson Ivo ToninSilva, Edimilson DomingosFerreira, Antônio Gomes PintoKrieger, Marco AurélioVeras, Patrícia Sampaio TavaresFraga, Deborah Bittencourt Mothé2018-12-13T16:36:44Z2018-12-13T16:36:44Z2018BORJA, L. S. et al. High accuracy of an ELISA test based in a flagella antigen of Leishmania in serodiagnosis of canine visceral leishmaniasis with potential to improve the control measures in Brazil - A Phase II study. PLoS Neglected Tropical Diseases, v. 12, n. 10, p. e0006871, 2018.1935-2727https://www.arca.fiocruz.br/handle/icict/3057810.1371/journal.pntd.0006871Instituto de Ciência e Tecnologia em Doenc¸as Tropicais (INCT-DT- Grant number: 576269/2008) and Fundac¸ão de Amparo a Pesquisa da Bahia (FAPESB – Grant number: JCB0010/2013).Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Laboratório de Interação Parasito-Hospedeiro e Epidemiologia. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Laboratório de Interação Parasito-Hospedeiro e Epidemiologia. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Laboratório de Interação Parasito-Hospedeiro e Epidemiologia. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Centro de Integração de Dados e Conhecimento para a Saúde. Salvador, BA, Brasil.Instituto de Biologia Molecular do Paraná. Curitiba, PR, Brasil.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil.Fundação Oswaldo Cruz. Instituto de Tecnologia em Imunobiológicos. Bio-Manguinhos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Tecnologia em Imunobiológicos. Bio-Manguinhos. Rio de Janeiro, RJ, Brasil.Instituto de Biologia Molecular do Paraná. Curitiba, PR, Brasil / Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Laboratório de Interação Parasito-Hospedeiro e Epidemiologia. Salvador, BA, Brasil / Instituto Nacional de Ciência e Tecnologia em Doenças Tropicais. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Laboratório de Interação Parasito-Hospedeiro e Epidemiologia. Salvador, BA, Brasil / Instituto Nacional de Ciência e Tecnologia em Doenças Tropicais. Salvador, BA, Brasil / Universidade Federal da Bahia. Escola de Medicina Veterinária. Salvador, BA, Brasil.Canine Visceral leishmaniasis (CVL) is a serious public health problem, thus for its control, the Ministry of Health in Brazil recommends the rapid diagnosis and euthanasia of seropositive dogs in endemic areas. Therefore, our group had previously selected six recombinant proteins (rLci1, rLci2, rLci4, rLci5, rLci8, and rLci12) due to their high potential for CVL diagnostic testing. The present study aims to produce an immunodiagnostic test using the aforementioned antigens, to improve the performance of the diagnosis of CVL recommended by Brazilian Ministry of Health.engPublic Library of ScienceLeishmaniaLeishmaniose visceralELISASorodiagnósticoAntígenoSaude públicaLeishmaniasisVisceral leishmaniasisELISASerodiagnosisAntigenPublic healthHigh accuracy of an ELISA test based in a flagella antigen of Leishmania in serodiagnosis of canine visceral leishmaniasis with potential to improve the control measures in Brazil - A Phase II studyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/30578/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALBorja LS High Accuracy of..2018.pdfBorja LS High Accuracy 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dc.title.pt_BR.fl_str_mv High accuracy of an ELISA test based in a flagella antigen of Leishmania in serodiagnosis of canine visceral leishmaniasis with potential to improve the control measures in Brazil - A Phase II study
title High accuracy of an ELISA test based in a flagella antigen of Leishmania in serodiagnosis of canine visceral leishmaniasis with potential to improve the control measures in Brazil - A Phase II study
spellingShingle High accuracy of an ELISA test based in a flagella antigen of Leishmania in serodiagnosis of canine visceral leishmaniasis with potential to improve the control measures in Brazil - A Phase II study
Borja, Lairton Souza
Leishmania
Leishmaniose visceral
ELISA
Sorodiagnóstico
Antígeno
Saude pública
Leishmaniasis
Visceral leishmaniasis
ELISA
Serodiagnosis
Antigen
Public health
title_short High accuracy of an ELISA test based in a flagella antigen of Leishmania in serodiagnosis of canine visceral leishmaniasis with potential to improve the control measures in Brazil - A Phase II study
title_full High accuracy of an ELISA test based in a flagella antigen of Leishmania in serodiagnosis of canine visceral leishmaniasis with potential to improve the control measures in Brazil - A Phase II study
title_fullStr High accuracy of an ELISA test based in a flagella antigen of Leishmania in serodiagnosis of canine visceral leishmaniasis with potential to improve the control measures in Brazil - A Phase II study
title_full_unstemmed High accuracy of an ELISA test based in a flagella antigen of Leishmania in serodiagnosis of canine visceral leishmaniasis with potential to improve the control measures in Brazil - A Phase II study
title_sort High accuracy of an ELISA test based in a flagella antigen of Leishmania in serodiagnosis of canine visceral leishmaniasis with potential to improve the control measures in Brazil - A Phase II study
author Borja, Lairton Souza
author_facet Borja, Lairton Souza
Coelho, Lívia Brito
Jesus, Matheus Silva de
Queiroz, Artur Trancoso Lopo de
Celedon, Paola Alejandra Fiorani
Zachin, Nilson Ivo Tonin
Silva, Edimilson Domingos
Ferreira, Antônio Gomes Pinto
Krieger, Marco Aurélio
Veras, Patrícia Sampaio Tavares
Fraga, Deborah Bittencourt Mothé
author_role author
author2 Coelho, Lívia Brito
Jesus, Matheus Silva de
Queiroz, Artur Trancoso Lopo de
Celedon, Paola Alejandra Fiorani
Zachin, Nilson Ivo Tonin
Silva, Edimilson Domingos
Ferreira, Antônio Gomes Pinto
Krieger, Marco Aurélio
Veras, Patrícia Sampaio Tavares
Fraga, Deborah Bittencourt Mothé
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Borja, Lairton Souza
Coelho, Lívia Brito
Jesus, Matheus Silva de
Queiroz, Artur Trancoso Lopo de
Celedon, Paola Alejandra Fiorani
Zachin, Nilson Ivo Tonin
Silva, Edimilson Domingos
Ferreira, Antônio Gomes Pinto
Krieger, Marco Aurélio
Veras, Patrícia Sampaio Tavares
Fraga, Deborah Bittencourt Mothé
dc.subject.other.pt_BR.fl_str_mv Leishmania
Leishmaniose visceral
ELISA
Sorodiagnóstico
Antígeno
Saude pública
topic Leishmania
Leishmaniose visceral
ELISA
Sorodiagnóstico
Antígeno
Saude pública
Leishmaniasis
Visceral leishmaniasis
ELISA
Serodiagnosis
Antigen
Public health
dc.subject.en.pt_BR.fl_str_mv Leishmaniasis
Visceral leishmaniasis
ELISA
Serodiagnosis
Antigen
Public health
description Instituto de Ciência e Tecnologia em Doenc¸as Tropicais (INCT-DT- Grant number: 576269/2008) and Fundac¸ão de Amparo a Pesquisa da Bahia (FAPESB – Grant number: JCB0010/2013).
publishDate 2018
dc.date.accessioned.fl_str_mv 2018-12-13T16:36:44Z
dc.date.available.fl_str_mv 2018-12-13T16:36:44Z
dc.date.issued.fl_str_mv 2018
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv BORJA, L. S. et al. High accuracy of an ELISA test based in a flagella antigen of Leishmania in serodiagnosis of canine visceral leishmaniasis with potential to improve the control measures in Brazil - A Phase II study. PLoS Neglected Tropical Diseases, v. 12, n. 10, p. e0006871, 2018.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/30578
dc.identifier.issn.pt_BR.fl_str_mv 1935-2727
dc.identifier.doi.none.fl_str_mv 10.1371/journal.pntd.0006871
identifier_str_mv BORJA, L. S. et al. High accuracy of an ELISA test based in a flagella antigen of Leishmania in serodiagnosis of canine visceral leishmaniasis with potential to improve the control measures in Brazil - A Phase II study. PLoS Neglected Tropical Diseases, v. 12, n. 10, p. e0006871, 2018.
1935-2727
10.1371/journal.pntd.0006871
url https://www.arca.fiocruz.br/handle/icict/30578
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Public Library of Science
publisher.none.fl_str_mv Public Library of Science
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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