Production of a scFv antagonistic to VLA-4 protein as a potential biopharmaceutical for chronic inflammatory diseases
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo de conferência |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/27260 |
Resumo: | Fundação Oswaldo Cruz. Instituto de Tecnologia em Imunobiológicos. Rio de Janeiro, RJ, Brasil. |
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Chaves, BeatrizAquino, Carolina LessaSilva, João Hermínio Martins daMedeiros, Marco AlbertoSavino, WilsonRiederer, IngoAlmeida, Vinícius Cotta de2018-07-03T19:34:39Z2018-07-03T19:34:39Z2018CHAVES, B. et al. Production of a scFv antagonistic to VLA-4 protein as a potential biopharmaceutical for chronic inflammatory diseases. In: SEMINÁRIO ANUAL CIENTÍFICO E TECNOLÓGICO DE BIO-MANGUINHOS, 6., 2018, Rio de Janeiro. Anais... Rio de Janeiro: Bio-Manguinhos, 2018. p. 60-61.https://www.arca.fiocruz.br/handle/icict/2726010.35259/isi.sact.2018_27260engFiocruz/Instituto de Tecnologia em ImunobiológicosscFvVLA-4DesenvolvimentoscFvVLA-4DevelopmentAnticorpos de Cadeia ÚnicaIntegrina alfa4beta1Crescimento e DesenvolvimentoProduction of a scFv antagonistic to VLA-4 protein as a potential biopharmaceutical for chronic inflammatory diseasesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectFundação Oswaldo Cruz. Instituto de Tecnologia em Imunobiológicos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Tecnologia em Imunobiológicos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Fiocruz Ceará. Fortaleza, CE, Brasil.Fundação Oswaldo Cruz. Instituto de Tecnologia em Imunobiológicos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/27260/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51TEXTBIO.08.pdf.txtBIO.08.pdf.txtExtracted texttext/plain1https://www.arca.fiocruz.br/bitstream/icict/27260/3/BIO.08.pdf.txt68b329da9893e34099c7d8ad5cb9c940MD53ORIGINALBIO.08.pdfBIO.08.pdfapplication/pdf174108https://www.arca.fiocruz.br/bitstream/icict/27260/4/BIO.08.pdf308020c32ce9946eafa5a3e2da318ee1MD54icict/272602023-04-26 17:06:26.571oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-04-26T20:06:26Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.pt_BR.fl_str_mv |
Production of a scFv antagonistic to VLA-4 protein as a potential biopharmaceutical for chronic inflammatory diseases |
title |
Production of a scFv antagonistic to VLA-4 protein as a potential biopharmaceutical for chronic inflammatory diseases |
spellingShingle |
Production of a scFv antagonistic to VLA-4 protein as a potential biopharmaceutical for chronic inflammatory diseases Chaves, Beatriz scFv VLA-4 Desenvolvimento scFv VLA-4 Development Anticorpos de Cadeia Única Integrina alfa4beta1 Crescimento e Desenvolvimento |
title_short |
Production of a scFv antagonistic to VLA-4 protein as a potential biopharmaceutical for chronic inflammatory diseases |
title_full |
Production of a scFv antagonistic to VLA-4 protein as a potential biopharmaceutical for chronic inflammatory diseases |
title_fullStr |
Production of a scFv antagonistic to VLA-4 protein as a potential biopharmaceutical for chronic inflammatory diseases |
title_full_unstemmed |
Production of a scFv antagonistic to VLA-4 protein as a potential biopharmaceutical for chronic inflammatory diseases |
title_sort |
Production of a scFv antagonistic to VLA-4 protein as a potential biopharmaceutical for chronic inflammatory diseases |
author |
Chaves, Beatriz |
author_facet |
Chaves, Beatriz Aquino, Carolina Lessa Silva, João Hermínio Martins da Medeiros, Marco Alberto Savino, Wilson Riederer, Ingo Almeida, Vinícius Cotta de |
author_role |
author |
author2 |
Aquino, Carolina Lessa Silva, João Hermínio Martins da Medeiros, Marco Alberto Savino, Wilson Riederer, Ingo Almeida, Vinícius Cotta de |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Chaves, Beatriz Aquino, Carolina Lessa Silva, João Hermínio Martins da Medeiros, Marco Alberto Savino, Wilson Riederer, Ingo Almeida, Vinícius Cotta de |
dc.subject.other.pt_BR.fl_str_mv |
scFv VLA-4 Desenvolvimento |
topic |
scFv VLA-4 Desenvolvimento scFv VLA-4 Development Anticorpos de Cadeia Única Integrina alfa4beta1 Crescimento e Desenvolvimento |
dc.subject.en.pt_BR.fl_str_mv |
scFv VLA-4 Development |
dc.subject.decs.pt_BR.fl_str_mv |
Anticorpos de Cadeia Única Integrina alfa4beta1 Crescimento e Desenvolvimento |
description |
Fundação Oswaldo Cruz. Instituto de Tecnologia em Imunobiológicos. Rio de Janeiro, RJ, Brasil. |
publishDate |
2018 |
dc.date.accessioned.fl_str_mv |
2018-07-03T19:34:39Z |
dc.date.available.fl_str_mv |
2018-07-03T19:34:39Z |
dc.date.issued.fl_str_mv |
2018 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/conferenceObject |
format |
conferenceObject |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
CHAVES, B. et al. Production of a scFv antagonistic to VLA-4 protein as a potential biopharmaceutical for chronic inflammatory diseases. In: SEMINÁRIO ANUAL CIENTÍFICO E TECNOLÓGICO DE BIO-MANGUINHOS, 6., 2018, Rio de Janeiro. Anais... Rio de Janeiro: Bio-Manguinhos, 2018. p. 60-61. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/27260 |
dc.identifier.doi.none.fl_str_mv |
10.35259/isi.sact.2018_27260 |
identifier_str_mv |
CHAVES, B. et al. Production of a scFv antagonistic to VLA-4 protein as a potential biopharmaceutical for chronic inflammatory diseases. In: SEMINÁRIO ANUAL CIENTÍFICO E TECNOLÓGICO DE BIO-MANGUINHOS, 6., 2018, Rio de Janeiro. Anais... Rio de Janeiro: Bio-Manguinhos, 2018. p. 60-61. 10.35259/isi.sact.2018_27260 |
url |
https://www.arca.fiocruz.br/handle/icict/27260 |
dc.language.iso.fl_str_mv |
eng |
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eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
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openAccess |
dc.publisher.none.fl_str_mv |
Fiocruz/Instituto de Tecnologia em Imunobiológicos |
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Fiocruz/Instituto de Tecnologia em Imunobiológicos |
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