Genetic Diversity of Brazilian Aedes aegypti: Patterns following an Eradication Program

Detalhes bibliográficos
Autor(a) principal: Monteiro, Fernando A.
Data de Publicação: 2014
Outros Autores: Shama, Renata, Martins, Ademir J., Gloria-Soria, Andrea, Brown, Julia E., Powell, Jeffrey R.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/10071
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratorio de Epidemiologia e Sistemática Molecular. Rio de Janeiro. RJ, Brasil.
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spelling Monteiro, Fernando A.Shama, RenataMartins, Ademir J.Gloria-Soria, AndreaBrown, Julia E.Powell, Jeffrey R.2015-04-17T17:04:33Z2015-04-17T17:04:33Z2014MONTEIRO, Fernando A et al. Diversity of Brazilian Aedes aegypti: Patterns following an Eradication Program. PLOS Neglected Tropical Diseases, v.8, n.9, 10p, 2014.https://www.arca.fiocruz.br/handle/icict/1007110.1371/journal.pntd.0003460engPlos OneAedes aegyptiBrasilSaúde PúblicaDengueGenetic patternsHealth PublicBrazilAedes aegyptiDengueSaúde PúblicaGenetic Diversity of Brazilian Aedes aegypti: Patterns following an Eradication Programinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratorio de Epidemiologia e Sistemática Molecular. Rio de Janeiro. RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Computacional e Sistemas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Fisiologia e Controle de Artrópodes Vetores. Rio de Janeiro, RJ, Brasil.Yale University. Department of Ecology and Evolutionary Biology. New Haven, Connecticut, USA.Yale University. Department of Ecology and Evolutionary Biology. New Haven, Connecticut, USA.Yale University. Department of Ecology and Evolutionary Biology. New Haven, Connecticut, USA.Background: Aedes aegypti is the most important vector of dengue fever in Brazil, where severe epidemics have recently taken place. Ae. aegypti in Brazil was the subject of an intense eradication program in the 1940s and 50s to control yellow fever. Brazil was the largest country declared free of this mosquito by the Pan-American Health Organization in 1958. Soon after relaxation of this program, Ae. aegypti reappeared in this country, and by the early 1980s dengue fever had been reported. The aim of this study is to analyze the present-day genetic patterns of Ae. aegypti populations in Brazil. Methodology/Principal Findings: We studied the genetic variation in samples of 11 widely spread populations of Ae. aegypti in Brazil based on 12 well-established microsatellite loci. Our principal finding is that present-day Brazilian Ae. aegypti populations form two distinct groups, one in the northwest and one in the southeast of the country. These two groups have genetic affinities to northern South American countries and the Caribbean, respectively. This is consistent with what has been reported for other genetic markers such as mitochondrial DNA and allele frequencies at the insecticide resistance gene, kdr. Conclusions/Significance: We conclude that the genetic patterns in present day populations of Ae. aegypti in Brazil are more consistent with a complete eradication of the species in the recent past followed by re-colonization, rather than the alternative possibility of expansion from residual pockets of refugia. At least two colonizations are likely to have taken place, one from northern South American countries (e.g., Venezuela) that founded the northwestern group, and one from the Caribbean that founded the southeastern group. The proposed source areas were never declared free of Ae. aegypti.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1914https://www.arca.fiocruz.br/bitstream/icict/10071/1/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD51ORIGINALfernando_monteiroetal_IOC_2014.pdfapplication/pdf2376719https://www.arca.fiocruz.br/bitstream/icict/10071/2/fernando_monteiroetal_IOC_2014.pdfa6ea28067933cc557198a459af8aee46MD52TEXTfernando_monteiroetal_IOC_2014.pdf.txtfernando_monteiroetal_IOC_2014.pdf.txtExtracted texttext/plain50700https://www.arca.fiocruz.br/bitstream/icict/10071/3/fernando_monteiroetal_IOC_2014.pdf.txt70b8f06cb33a8e3abfd2762816c32568MD53icict/100712022-06-24 13:08:47.326oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-06-24T16:08:47Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Genetic Diversity of Brazilian Aedes aegypti: Patterns following an Eradication Program
title Genetic Diversity of Brazilian Aedes aegypti: Patterns following an Eradication Program
spellingShingle Genetic Diversity of Brazilian Aedes aegypti: Patterns following an Eradication Program
Monteiro, Fernando A.
Aedes aegypti
Brasil
Saúde Pública
Dengue
Genetic patterns
Health Public
Brazil
Aedes aegypti
Dengue
Saúde Pública
title_short Genetic Diversity of Brazilian Aedes aegypti: Patterns following an Eradication Program
title_full Genetic Diversity of Brazilian Aedes aegypti: Patterns following an Eradication Program
title_fullStr Genetic Diversity of Brazilian Aedes aegypti: Patterns following an Eradication Program
title_full_unstemmed Genetic Diversity of Brazilian Aedes aegypti: Patterns following an Eradication Program
title_sort Genetic Diversity of Brazilian Aedes aegypti: Patterns following an Eradication Program
author Monteiro, Fernando A.
author_facet Monteiro, Fernando A.
Shama, Renata
Martins, Ademir J.
Gloria-Soria, Andrea
Brown, Julia E.
Powell, Jeffrey R.
author_role author
author2 Shama, Renata
Martins, Ademir J.
Gloria-Soria, Andrea
Brown, Julia E.
Powell, Jeffrey R.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Monteiro, Fernando A.
Shama, Renata
Martins, Ademir J.
Gloria-Soria, Andrea
Brown, Julia E.
Powell, Jeffrey R.
dc.subject.other.pt_BR.fl_str_mv Aedes aegypti
Brasil
Saúde Pública
Dengue
Genetic patterns
topic Aedes aegypti
Brasil
Saúde Pública
Dengue
Genetic patterns
Health Public
Brazil
Aedes aegypti
Dengue
Saúde Pública
dc.subject.en.pt_BR.fl_str_mv Health Public
Brazil
Aedes aegypti
Dengue
dc.subject.decs.pt_BR.fl_str_mv Saúde Pública
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratorio de Epidemiologia e Sistemática Molecular. Rio de Janeiro. RJ, Brasil.
publishDate 2014
dc.date.issued.fl_str_mv 2014
dc.date.accessioned.fl_str_mv 2015-04-17T17:04:33Z
dc.date.available.fl_str_mv 2015-04-17T17:04:33Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv MONTEIRO, Fernando A et al. Diversity of Brazilian Aedes aegypti: Patterns following an Eradication Program. PLOS Neglected Tropical Diseases, v.8, n.9, 10p, 2014.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/10071
dc.identifier.doi.pt_BR.fl_str_mv 10.1371/journal.pntd.0003460
identifier_str_mv MONTEIRO, Fernando A et al. Diversity of Brazilian Aedes aegypti: Patterns following an Eradication Program. PLOS Neglected Tropical Diseases, v.8, n.9, 10p, 2014.
10.1371/journal.pntd.0003460
url https://www.arca.fiocruz.br/handle/icict/10071
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Plos One
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dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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