Leishmania (Viannia) naiffi: rare enough to be neglected?
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2015 |
| Outros Autores: | , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/12204 |
Resumo: | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório Interdisciplinar de Pesquisas Médicas, Rio de Janeiro, RJ, Brasil. |
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Silva, Giselle Aparecida FagundesRomero, Gustavo Adolfo SierraCupolillo, ElisaYamashita, Ellen Priscila GadelhaSilva, Adriano GomesGuerra, Jorge Augusto de OliveiraCruz, Alda Maria da2015-11-12T13:07:03Z2015-11-12T13:07:03Z2015SILVA, Giselle Aparecida Fagundes; et al. Leishmania (Viannia) naiffi: rare enough to be neglected?. Mem Inst Oswaldo Cruz, v.110, n.6, p.797-800, Sept. 2015.0074-0276https://www.arca.fiocruz.br/handle/icict/1220410.1590/0074-027601501281678-8060engFundação Oswaldo CruzAmazôniaLeishmania (Viannia) naiffiTherapeutic failureClinical outcomeMultilocus enzyme electrophoresisAmazon RegionAmerican tegumentary leishmaniasis (ATL)LeishmaniaLeishmania (Viannia) naiffi: rare enough to be neglected?info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório Interdisciplinar de Pesquisas Médicas, Rio de Janeiro, RJ, Brasil.Universidade de Brasília. Faculdade de Medicina. Núcleo de Medicina Tropical. Brasília, DF, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisas em Leishmaniose. Rio de Janeiro, RJ, Brasil.Fundação de Medicina Tropical Dr Heitor Vieira Dourado. Gerência de Leishmaniose. Manaus, AM, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório Interdisciplinar de Pesquisas Médicas, Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Plataforma de Laboratório Multiusuário. Rio de Janeiro, RJ, Brasil.Fundação de Medicina Tropical Dr Heitor Vieira Dourado. Gerência de Leishmaniose. Manaus, AM, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório Interdisciplinar de Pesquisas Médicas, Rio de Janeiro, RJ, Brasil.In the Brazilian Amazon, American tegumentary leishmaniasis (ATL) is endemic and presents a wide spectrum of clinical manifestations due, in part, to the circulation of at least seven Leishmania species. Few reports of Leishmania (Viannia) naiffi infection suggest that its occurrence is uncommon and the reported cases present a benign clinical course and a good response to treatment. This study aimed to strengthen the clinical and epidemiological importance of L. (V.) naiffi in the Amazon Region (Manaus, state of Amazonas) and to report therapeutic failure in patients infected with this species. Thirty Leishmania spp samples isolated from cutaneous lesions were characterised by multilocus enzyme electrophoresis. As expected, the most common species was Leishmania (V.) guyanensis (20 cases). However, a relevant number of L. (V.) naiffi patients (8 cases) was observed, thus demonstrating that this species is not uncommon in the region. No patient infected with L. (V.) naiffi evolved to spontaneous cure until the start of treatment, which indicated that this species may not have a self-limiting nature. In addition, two of the patients experienced a poor response to antimonial or pentamidine therapy. Thus, either ATL cases due to L. (V.) naiffi cannot be as uncommon as previously thought or this species is currently expanding in this region.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/12204/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALgisele_silva_etal_IOC_2015.pdfgisele_silva_etal_IOC_2015.pdfapplication/pdf189519https://www.arca.fiocruz.br/bitstream/icict/12204/2/gisele_silva_etal_IOC_2015.pdf3fcb858631cd7bea042e63833e1ea2ceMD52TEXTgisele_silva_etal_IOC_2015.pdf.txtgisele_silva_etal_IOC_2015.pdf.txtExtracted texttext/plain18936https://www.arca.fiocruz.br/bitstream/icict/12204/3/gisele_silva_etal_IOC_2015.pdf.txt490cee43c709869dd66566c0b4f28fc6MD53icict/122042023-09-05 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| dc.title.pt_BR.fl_str_mv |
Leishmania (Viannia) naiffi: rare enough to be neglected? |
| title |
Leishmania (Viannia) naiffi: rare enough to be neglected? |
| spellingShingle |
Leishmania (Viannia) naiffi: rare enough to be neglected? Silva, Giselle Aparecida Fagundes Amazônia Leishmania (Viannia) naiffi Therapeutic failure Clinical outcome Multilocus enzyme electrophoresis Amazon Region American tegumentary leishmaniasis (ATL) Leishmania |
| title_short |
Leishmania (Viannia) naiffi: rare enough to be neglected? |
| title_full |
Leishmania (Viannia) naiffi: rare enough to be neglected? |
| title_fullStr |
Leishmania (Viannia) naiffi: rare enough to be neglected? |
| title_full_unstemmed |
Leishmania (Viannia) naiffi: rare enough to be neglected? |
| title_sort |
Leishmania (Viannia) naiffi: rare enough to be neglected? |
| author |
Silva, Giselle Aparecida Fagundes |
| author_facet |
Silva, Giselle Aparecida Fagundes Romero, Gustavo Adolfo Sierra Cupolillo, Elisa Yamashita, Ellen Priscila Gadelha Silva, Adriano Gomes Guerra, Jorge Augusto de Oliveira Cruz, Alda Maria da |
| author_role |
author |
| author2 |
Romero, Gustavo Adolfo Sierra Cupolillo, Elisa Yamashita, Ellen Priscila Gadelha Silva, Adriano Gomes Guerra, Jorge Augusto de Oliveira Cruz, Alda Maria da |
| author2_role |
author author author author author author |
| dc.contributor.author.fl_str_mv |
Silva, Giselle Aparecida Fagundes Romero, Gustavo Adolfo Sierra Cupolillo, Elisa Yamashita, Ellen Priscila Gadelha Silva, Adriano Gomes Guerra, Jorge Augusto de Oliveira Cruz, Alda Maria da |
| dc.subject.other.pt_BR.fl_str_mv |
Amazônia |
| topic |
Amazônia Leishmania (Viannia) naiffi Therapeutic failure Clinical outcome Multilocus enzyme electrophoresis Amazon Region American tegumentary leishmaniasis (ATL) Leishmania |
| dc.subject.en.pt_BR.fl_str_mv |
Leishmania (Viannia) naiffi Therapeutic failure Clinical outcome Multilocus enzyme electrophoresis Amazon Region American tegumentary leishmaniasis (ATL) |
| dc.subject.decs.pt_BR.fl_str_mv |
Leishmania |
| description |
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório Interdisciplinar de Pesquisas Médicas, Rio de Janeiro, RJ, Brasil. |
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2015 |
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2015-11-12T13:07:03Z |
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2015-11-12T13:07:03Z |
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2015 |
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info:eu-repo/semantics/article |
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SILVA, Giselle Aparecida Fagundes; et al. Leishmania (Viannia) naiffi: rare enough to be neglected?. Mem Inst Oswaldo Cruz, v.110, n.6, p.797-800, Sept. 2015. |
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https://www.arca.fiocruz.br/handle/icict/12204 |
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0074-0276 |
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10.1590/0074-02760150128 |
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1678-8060 |
| identifier_str_mv |
SILVA, Giselle Aparecida Fagundes; et al. Leishmania (Viannia) naiffi: rare enough to be neglected?. Mem Inst Oswaldo Cruz, v.110, n.6, p.797-800, Sept. 2015. 0074-0276 10.1590/0074-02760150128 1678-8060 |
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