Aptamers in the diagnosis of Rickettsiosis sensu lato
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/9898 |
Resumo: | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickttesiose. Rio de Janeiro, RJ, Brasil. |
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Godoy, Daniela Tupy deMissailidis, SotirisFavacho, Alexsandra R. M.Mares-Guia, Maria Angélica M. M.Rozental, TatianaLemos, Elba Regina Sampaio2015-04-06T17:18:22Z2015-04-06T17:18:22Z2014GODOY, D. T.; et al. Aptamers in the diagnosis of rickettsiosis sensu lato. Virus Reviews and Research, v.19, p. 9-14,2014.15192563https://www.arca.fiocruz.br/handle/icict/9898engBrazilian Society for Virology (SBV)Sociedade Brasileira de VirologiaAptamers in the diagnosis of Rickettsiosis sensu latoinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickttesiose. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickttesiose. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickttesiose. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickttesiose. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickttesiose. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickttesiose. Rio de Janeiro, RJ, Brasil.Aptamers are short synthetic oligonucleotides that specifi cally bind to various molecular targets with high affi nity and selectivity. Aptamers have found two main applications in bacteriology, diagnosis in various sensing applications and riboswitches. Rickettsiosis are diseases caused by rickettsias ‘sensu lato’ including spotted fever, typhus, anaplasmosis, ehrlichiosis, bartonellosis and Q fever. Traditional methodologies for the diagnosis of diseases associated with rickettsias ‘sensu lato’ are based on serological testing, bacterial cultures and molecular assays. However, an increasing number of novel technologies, including aptamer-based diagnostic sensors, are now on the horizon, opening up possibilities for earlier diagnosis and more sensitive assays. Th is perspective looks at the contribution of aptamers to rickettsias ‘sensu lato’ diagnosis, providing information on the ‘state of the art’ in this emerging fieldBiosafetyRodentFieldworkCarcinoma BasocelularExposição a Agentes Biológicosinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALdaniela_godoyetal_IOC_2014.pdfapplication/pdf92284https://www.arca.fiocruz.br/bitstream/icict/9898/1/daniela_godoyetal_IOC_2014.pdf4fa12f8fcfa66d60fbcab5a9a584529aMD51LICENSElicense.txttext/plain1914https://www.arca.fiocruz.br/bitstream/icict/9898/2/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD52TEXTdaniela_godoyetal_IOC_2014.pdf.txtdaniela_godoyetal_IOC_2014.pdf.txtExtracted texttext/plain31644https://www.arca.fiocruz.br/bitstream/icict/9898/3/daniela_godoyetal_IOC_2014.pdf.txteaeabee0ddeff608bc9d4236cf3f996eMD53icict/98982022-06-24 12:18:53.554oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-06-24T15:18:53Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.pt_BR.fl_str_mv |
Aptamers in the diagnosis of Rickettsiosis sensu lato |
title |
Aptamers in the diagnosis of Rickettsiosis sensu lato |
spellingShingle |
Aptamers in the diagnosis of Rickettsiosis sensu lato Godoy, Daniela Tupy de Biosafety Rodent Fieldwork Carcinoma Basocelular Exposição a Agentes Biológicos |
title_short |
Aptamers in the diagnosis of Rickettsiosis sensu lato |
title_full |
Aptamers in the diagnosis of Rickettsiosis sensu lato |
title_fullStr |
Aptamers in the diagnosis of Rickettsiosis sensu lato |
title_full_unstemmed |
Aptamers in the diagnosis of Rickettsiosis sensu lato |
title_sort |
Aptamers in the diagnosis of Rickettsiosis sensu lato |
author |
Godoy, Daniela Tupy de |
author_facet |
Godoy, Daniela Tupy de Missailidis, Sotiris Favacho, Alexsandra R. M. Mares-Guia, Maria Angélica M. M. Rozental, Tatiana Lemos, Elba Regina Sampaio |
author_role |
author |
author2 |
Missailidis, Sotiris Favacho, Alexsandra R. M. Mares-Guia, Maria Angélica M. M. Rozental, Tatiana Lemos, Elba Regina Sampaio |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Godoy, Daniela Tupy de Missailidis, Sotiris Favacho, Alexsandra R. M. Mares-Guia, Maria Angélica M. M. Rozental, Tatiana Lemos, Elba Regina Sampaio |
dc.subject.en.en.fl_str_mv |
Biosafety Rodent Fieldwork |
topic |
Biosafety Rodent Fieldwork Carcinoma Basocelular Exposição a Agentes Biológicos |
dc.subject.decs.pt_BR.fl_str_mv |
Carcinoma Basocelular |
dc.subject.decs.pt.fl_str_mv |
Exposição a Agentes Biológicos |
description |
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickttesiose. Rio de Janeiro, RJ, Brasil. |
publishDate |
2014 |
dc.date.issued.fl_str_mv |
2014 |
dc.date.accessioned.fl_str_mv |
2015-04-06T17:18:22Z |
dc.date.available.fl_str_mv |
2015-04-06T17:18:22Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
GODOY, D. T.; et al. Aptamers in the diagnosis of rickettsiosis sensu lato. Virus Reviews and Research, v.19, p. 9-14,2014. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/9898 |
dc.identifier.issn.pt_BR.fl_str_mv |
15192563 |
identifier_str_mv |
GODOY, D. T.; et al. Aptamers in the diagnosis of rickettsiosis sensu lato. Virus Reviews and Research, v.19, p. 9-14,2014. 15192563 |
url |
https://www.arca.fiocruz.br/handle/icict/9898 |
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eng |
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eng |
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openAccess |
dc.publisher.none.fl_str_mv |
Brazilian Society for Virology (SBV) Sociedade Brasileira de Virologia |
publisher.none.fl_str_mv |
Brazilian Society for Virology (SBV) Sociedade Brasileira de Virologia |
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