Aptamers in the diagnosis of Rickettsiosis sensu lato

Detalhes bibliográficos
Autor(a) principal: Godoy, Daniela Tupy de
Data de Publicação: 2014
Outros Autores: Missailidis, Sotiris, Favacho, Alexsandra R. M., Mares-Guia, Maria Angélica M. M., Rozental, Tatiana, Lemos, Elba Regina Sampaio
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/9898
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickttesiose. Rio de Janeiro, RJ, Brasil.
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spelling Godoy, Daniela Tupy deMissailidis, SotirisFavacho, Alexsandra R. M.Mares-Guia, Maria Angélica M. M.Rozental, TatianaLemos, Elba Regina Sampaio2015-04-06T17:18:22Z2015-04-06T17:18:22Z2014GODOY, D. T.; et al. Aptamers in the diagnosis of rickettsiosis sensu lato. Virus Reviews and Research, v.19, p. 9-14,2014.15192563https://www.arca.fiocruz.br/handle/icict/9898engBrazilian Society for Virology (SBV)Sociedade Brasileira de VirologiaAptamers in the diagnosis of Rickettsiosis sensu latoinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickttesiose. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickttesiose. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickttesiose. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickttesiose. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickttesiose. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickttesiose. Rio de Janeiro, RJ, Brasil.Aptamers are short synthetic oligonucleotides that specifi cally bind to various molecular targets with high affi nity and selectivity. Aptamers have found two main applications in bacteriology, diagnosis in various sensing applications and riboswitches. Rickettsiosis are diseases caused by rickettsias ‘sensu lato’ including spotted fever, typhus, anaplasmosis, ehrlichiosis, bartonellosis and Q fever. Traditional methodologies for the diagnosis of diseases associated with rickettsias ‘sensu lato’ are based on serological testing, bacterial cultures and molecular assays. However, an increasing number of novel technologies, including aptamer-based diagnostic sensors, are now on the horizon, opening up possibilities for earlier diagnosis and more sensitive assays. Th is perspective looks at the contribution of aptamers to rickettsias ‘sensu lato’ diagnosis, providing information on the ‘state of the art’ in this emerging fieldBiosafetyRodentFieldworkCarcinoma BasocelularExposição a Agentes Biológicosinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALdaniela_godoyetal_IOC_2014.pdfapplication/pdf92284https://www.arca.fiocruz.br/bitstream/icict/9898/1/daniela_godoyetal_IOC_2014.pdf4fa12f8fcfa66d60fbcab5a9a584529aMD51LICENSElicense.txttext/plain1914https://www.arca.fiocruz.br/bitstream/icict/9898/2/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD52TEXTdaniela_godoyetal_IOC_2014.pdf.txtdaniela_godoyetal_IOC_2014.pdf.txtExtracted texttext/plain31644https://www.arca.fiocruz.br/bitstream/icict/9898/3/daniela_godoyetal_IOC_2014.pdf.txteaeabee0ddeff608bc9d4236cf3f996eMD53icict/98982022-06-24 12:18:53.554oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-06-24T15:18:53Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Aptamers in the diagnosis of Rickettsiosis sensu lato
title Aptamers in the diagnosis of Rickettsiosis sensu lato
spellingShingle Aptamers in the diagnosis of Rickettsiosis sensu lato
Godoy, Daniela Tupy de
Biosafety
Rodent
Fieldwork
Carcinoma Basocelular
Exposição a Agentes Biológicos
title_short Aptamers in the diagnosis of Rickettsiosis sensu lato
title_full Aptamers in the diagnosis of Rickettsiosis sensu lato
title_fullStr Aptamers in the diagnosis of Rickettsiosis sensu lato
title_full_unstemmed Aptamers in the diagnosis of Rickettsiosis sensu lato
title_sort Aptamers in the diagnosis of Rickettsiosis sensu lato
author Godoy, Daniela Tupy de
author_facet Godoy, Daniela Tupy de
Missailidis, Sotiris
Favacho, Alexsandra R. M.
Mares-Guia, Maria Angélica M. M.
Rozental, Tatiana
Lemos, Elba Regina Sampaio
author_role author
author2 Missailidis, Sotiris
Favacho, Alexsandra R. M.
Mares-Guia, Maria Angélica M. M.
Rozental, Tatiana
Lemos, Elba Regina Sampaio
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Godoy, Daniela Tupy de
Missailidis, Sotiris
Favacho, Alexsandra R. M.
Mares-Guia, Maria Angélica M. M.
Rozental, Tatiana
Lemos, Elba Regina Sampaio
dc.subject.en.en.fl_str_mv Biosafety
Rodent
Fieldwork
topic Biosafety
Rodent
Fieldwork
Carcinoma Basocelular
Exposição a Agentes Biológicos
dc.subject.decs.pt_BR.fl_str_mv Carcinoma Basocelular
dc.subject.decs.pt.fl_str_mv Exposição a Agentes Biológicos
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickttesiose. Rio de Janeiro, RJ, Brasil.
publishDate 2014
dc.date.issued.fl_str_mv 2014
dc.date.accessioned.fl_str_mv 2015-04-06T17:18:22Z
dc.date.available.fl_str_mv 2015-04-06T17:18:22Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv GODOY, D. T.; et al. Aptamers in the diagnosis of rickettsiosis sensu lato. Virus Reviews and Research, v.19, p. 9-14,2014.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/9898
dc.identifier.issn.pt_BR.fl_str_mv 15192563
identifier_str_mv GODOY, D. T.; et al. Aptamers in the diagnosis of rickettsiosis sensu lato. Virus Reviews and Research, v.19, p. 9-14,2014.
15192563
url https://www.arca.fiocruz.br/handle/icict/9898
dc.language.iso.fl_str_mv eng
language eng
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dc.publisher.none.fl_str_mv Brazilian Society for Virology (SBV)
Sociedade Brasileira de Virologia
publisher.none.fl_str_mv Brazilian Society for Virology (SBV)
Sociedade Brasileira de Virologia
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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