Destruction of Schistosoma mansoni sporocysts in Biomphalaria glabrata after phytochemical exposure

Detalhes bibliográficos
Autor(a) principal: Friani, Gabriela
Data de Publicação: 2022
Outros Autores: Costa, Valdir A., Mota, Ester, Faro, Marta Júlia, Souza, Samaly, Figueiredo, Marcela, Gôlo, Patrícia S., Silva, Clélia Christina
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/53922
Resumo: Universidade Federal Rural do Rio de Janeiro, Curso de Pós-Graduação em Ciências Veterinárias, Instituto de Veterinária. Seropédica, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Avaliação e Promoção da Saúde Ambiental. Rio de Janeiro, RJ, Brasil.
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spelling Friani, GabrielaCosta, Valdir A.Mota, EsterFaro, Marta JúliaSouza, SamalyFigueiredo, MarcelaGôlo, Patrícia S.Silva, Clélia Christina2022-07-22T21:00:24Z2022-07-22T21:00:24Z2022FRIANI, Gabriela et al. Destruction of Schistosoma mansoni sporocysts in Biomphalaria glabrata after phytochemical exposure. An Acad Bras Ciências, Rio de Janeiro, v. 94, n. 2, e20190676, p. 1 - 10, 2022.1678-2690https://www.arca.fiocruz.br/handle/icict/5392210.1590/0001-3765202220200620engAcademia Brasileira de CiênciasBiomphalariaGlabrataEuphorbia miliiHemócitosFitoquímicoSuscetibilidadeBiomphalariaGlabrataEuphorbia miliiHemocytesPhytochemicalSusceptibilityDestruction of Schistosoma mansoni sporocysts in Biomphalaria glabrata after phytochemical exposureinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal Rural do Rio de Janeiro, Curso de Pós-Graduação em Ciências Veterinárias, Instituto de Veterinária. Seropédica, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Avaliação e Promoção da Saúde Ambiental. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Laboratório de Esquistossomose. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Patologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia e Parasitologia de Mamíferos Silvestres Reservatórios. Rio de Janeiro, RJ, Brasil.Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30329, USA.Swansea University, Medical School, Applies Molecular Microbiology Group, Singleton Park, Sketty, Swansea, SA2 8PP, UK.Universidade Federal Rural do Rio de Janeiro, Curso de Pós-Graduação em Ciências Veterinárias, Instituto de Veterinária. Seropédica, RJ, Brasil / Universidade Federal Rural do Rio de Janeiro. Instituto de Veterinária. Depatrtamento de Parasitologia Animal. Seropédica, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Avaliação e Promoção da Saúde Ambiental. Rio de Janeiro, RJ, Brasil.Schistosomiasis is a neglected tropical disease and affects over 200 million people worldwide. The snail Biomphalaria glabrata is one of the intermediate hosts of S. mansoni. The aim of this work was to verify the action of Euphorbia milii var. hislopii latex in the hemocytes profile and histopathology of B. glabrata infected by S. mansoni. Uninfected and infected snails were exposed to sublethal concentration of E. milii latex for 24 hours (1.0 mg/L). The survival rate was 88.5% for the uninfected snails and 66.6% for the infected and exposed snails. In the snails infected by S. mansoni, the exposure to E. milii latex promoted proliferation of hemocytes in the tentacles, mantle, digestive gland and kidney. In the digestive gland and the kidney, granulomatous reactions occurred around the sporocysts and caused their destruction. The number of circulating hemocytes from the group infected and exposed to E. milii latex was significantly higher than in the other groups. Three types of hemocytes were found: hyalinocytes, granulocytes and blast-like cells. We conclude that the E. milii latex influenced the cellular immune response of the susceptible B. glabrata strain to infection by S. mansoni, promoting the destruction of parasites.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/53922/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALGabrielaLeite_EsterMota_etal_IOC_2022.pdfGabrielaLeite_EsterMota_etal_IOC_2022.pdfapplication/pdf1556281https://www.arca.fiocruz.br/bitstream/icict/53922/2/GabrielaLeite_EsterMota_etal_IOC_2022.pdf07a8fb29c4d4ad7ea6e3e510b8d9613bMD52icict/539222022-07-22 18:00:24.4oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-07-22T21:00:24Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Destruction of Schistosoma mansoni sporocysts in Biomphalaria glabrata after phytochemical exposure
title Destruction of Schistosoma mansoni sporocysts in Biomphalaria glabrata after phytochemical exposure
spellingShingle Destruction of Schistosoma mansoni sporocysts in Biomphalaria glabrata after phytochemical exposure
Friani, Gabriela
Biomphalaria
Glabrata
Euphorbia milii
Hemócitos
Fitoquímico
Suscetibilidade
Biomphalaria
Glabrata
Euphorbia milii
Hemocytes
Phytochemical
Susceptibility
title_short Destruction of Schistosoma mansoni sporocysts in Biomphalaria glabrata after phytochemical exposure
title_full Destruction of Schistosoma mansoni sporocysts in Biomphalaria glabrata after phytochemical exposure
title_fullStr Destruction of Schistosoma mansoni sporocysts in Biomphalaria glabrata after phytochemical exposure
title_full_unstemmed Destruction of Schistosoma mansoni sporocysts in Biomphalaria glabrata after phytochemical exposure
title_sort Destruction of Schistosoma mansoni sporocysts in Biomphalaria glabrata after phytochemical exposure
author Friani, Gabriela
author_facet Friani, Gabriela
Costa, Valdir A.
Mota, Ester
Faro, Marta Júlia
Souza, Samaly
Figueiredo, Marcela
Gôlo, Patrícia S.
Silva, Clélia Christina
author_role author
author2 Costa, Valdir A.
Mota, Ester
Faro, Marta Júlia
Souza, Samaly
Figueiredo, Marcela
Gôlo, Patrícia S.
Silva, Clélia Christina
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Friani, Gabriela
Costa, Valdir A.
Mota, Ester
Faro, Marta Júlia
Souza, Samaly
Figueiredo, Marcela
Gôlo, Patrícia S.
Silva, Clélia Christina
dc.subject.other.pt_BR.fl_str_mv Biomphalaria
Glabrata
Euphorbia milii
Hemócitos
Fitoquímico
Suscetibilidade
topic Biomphalaria
Glabrata
Euphorbia milii
Hemócitos
Fitoquímico
Suscetibilidade
Biomphalaria
Glabrata
Euphorbia milii
Hemocytes
Phytochemical
Susceptibility
dc.subject.en.pt_BR.fl_str_mv Biomphalaria
Glabrata
Euphorbia milii
Hemocytes
Phytochemical
Susceptibility
description Universidade Federal Rural do Rio de Janeiro, Curso de Pós-Graduação em Ciências Veterinárias, Instituto de Veterinária. Seropédica, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Avaliação e Promoção da Saúde Ambiental. Rio de Janeiro, RJ, Brasil.
publishDate 2022
dc.date.accessioned.fl_str_mv 2022-07-22T21:00:24Z
dc.date.available.fl_str_mv 2022-07-22T21:00:24Z
dc.date.issued.fl_str_mv 2022
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv FRIANI, Gabriela et al. Destruction of Schistosoma mansoni sporocysts in Biomphalaria glabrata after phytochemical exposure. An Acad Bras Ciências, Rio de Janeiro, v. 94, n. 2, e20190676, p. 1 - 10, 2022.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/53922
dc.identifier.issn.pt_BR.fl_str_mv 1678-2690
dc.identifier.doi.none.fl_str_mv 10.1590/0001-3765202220200620
identifier_str_mv FRIANI, Gabriela et al. Destruction of Schistosoma mansoni sporocysts in Biomphalaria glabrata after phytochemical exposure. An Acad Bras Ciências, Rio de Janeiro, v. 94, n. 2, e20190676, p. 1 - 10, 2022.
1678-2690
10.1590/0001-3765202220200620
url https://www.arca.fiocruz.br/handle/icict/53922
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Academia Brasileira de Ciências
publisher.none.fl_str_mv Academia Brasileira de Ciências
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/53922/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/53922/2/GabrielaLeite_EsterMota_etal_IOC_2022.pdf
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