Fungal extracellular vesicles: modulating host–pathogen interactions by both the fungus and the host

Detalhes bibliográficos
Autor(a) principal: Zamith-Miranda, D.
Data de Publicação: 2018
Outros Autores: Nimrichter, L., Rodrigues, M. L., Nosanchuk, J. D.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/59581
Resumo: Department of Microbiology and Immunology. Albert Einstein College of Medicine. USA / Division of Infectious Diseases. Department of Medicine. Albert Einstein College of Medicine. USA.
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spelling Zamith-Miranda, D.Nimrichter, L.Rodrigues, M. L.Nosanchuk, J. D.2023-07-13T23:55:23Z2023-07-13T23:55:23Z2018ZAMITH-MIRANDA, D. et al. Fungal extracellular vesicles: modulating host–pathogen interactions by both the fungus and the host. Microbes and Infection, v. 20, n. 9-10, p. 501-501, 2018.1286-4579https://www.arca.fiocruz.br/handle/icict/5958110.1016/J.MICINF.2018.01.0111769-714XengElsevierBiological TransportCell CommunicationExtracellular VesiclesFungal ProteinsFungiHost-Pathogen InteractionsImmune EvasionSpecies SpecificityFungusExtracellular vesiclesCryptococcusHistoplasmaParacoccidioidesCandidapathogenesisFungal extracellular vesicles: modulating host–pathogen interactions by both the fungus and the hostinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleDepartment of Microbiology and Immunology. Albert Einstein College of Medicine. USA / Division of Infectious Diseases. Department of Medicine. Albert Einstein College of Medicine. USA.Universidade Federal do Rio de Janeiro. Instituto de Microbiologia Paulo de Góes. Rio de Janeiro, RJ, Brazil.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brazil.Department of Microbiology and Immunology. Albert Einstein College of Medicine. USA / Division of Infectious Diseases. Department of Medicine. Albert Einstein College of Medicine. USA.Fundação Oswaldo Cruz. Centro de Desenvolvimento Tecnológico em Saúde. Rio de Janeiro, RJ, Brasil.The secretion of biomolecules by fungal cells occurs via the conventional export of signal peptide-coupled soluble molecules, but it also results from transport within extracellular vesicles (EV). During the last ten years since the description of this non-conventional secretion pathway, varied, interesting biological roles have been associated with EV release by fungi. The various organic molecules carried by these structures are involved in pathogenesis and immune evasion, and may be associated with cell-cell communication. In regards to host-pathogen interactions, EV roles are diverse and organism-specific, although some features seem to be conserved among the pathogenic fungal organisms studied to date. This review aims to highlight our current understanding of the biologically relevant findings regarding EV released by the pathogenic fungal organisms and describes our knowledge of the roles of EV in host-pathogen interactions.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/59581/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINAL10.1016_j.micinf.2018.01.011.pdfapplication/pdf399668https://www.arca.fiocruz.br/bitstream/icict/59581/2/10.1016_j.micinf.2018.01.011.pdf8d1eb2e04c6d5d071d598cef315d0448MD52icict/595812023-07-13 21:39:39.78oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-07-14T00:39:39Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.en_US.fl_str_mv Fungal extracellular vesicles: modulating host–pathogen interactions by both the fungus and the host
title Fungal extracellular vesicles: modulating host–pathogen interactions by both the fungus and the host
spellingShingle Fungal extracellular vesicles: modulating host–pathogen interactions by both the fungus and the host
Zamith-Miranda, D.
Biological Transport
Cell Communication
Extracellular Vesicles
Fungal Proteins
Fungi
Host-Pathogen Interactions
Immune Evasion
Species Specificity
Fungus
Extracellular vesicles
Cryptococcus
Histoplasma
Paracoccidioides
Candida
pathogenesis
title_short Fungal extracellular vesicles: modulating host–pathogen interactions by both the fungus and the host
title_full Fungal extracellular vesicles: modulating host–pathogen interactions by both the fungus and the host
title_fullStr Fungal extracellular vesicles: modulating host–pathogen interactions by both the fungus and the host
title_full_unstemmed Fungal extracellular vesicles: modulating host–pathogen interactions by both the fungus and the host
title_sort Fungal extracellular vesicles: modulating host–pathogen interactions by both the fungus and the host
author Zamith-Miranda, D.
author_facet Zamith-Miranda, D.
Nimrichter, L.
Rodrigues, M. L.
Nosanchuk, J. D.
author_role author
author2 Nimrichter, L.
Rodrigues, M. L.
Nosanchuk, J. D.
author2_role author
author
author
dc.contributor.author.fl_str_mv Zamith-Miranda, D.
Nimrichter, L.
Rodrigues, M. L.
Nosanchuk, J. D.
dc.subject.mesh.en_US.fl_str_mv Biological Transport
Cell Communication
Extracellular Vesicles
Fungal Proteins
Fungi
Host-Pathogen Interactions
Immune Evasion
Species Specificity
topic Biological Transport
Cell Communication
Extracellular Vesicles
Fungal Proteins
Fungi
Host-Pathogen Interactions
Immune Evasion
Species Specificity
Fungus
Extracellular vesicles
Cryptococcus
Histoplasma
Paracoccidioides
Candida
pathogenesis
dc.subject.en.en_US.fl_str_mv Fungus
Extracellular vesicles
Cryptococcus
Histoplasma
Paracoccidioides
Candida
pathogenesis
description Department of Microbiology and Immunology. Albert Einstein College of Medicine. USA / Division of Infectious Diseases. Department of Medicine. Albert Einstein College of Medicine. USA.
publishDate 2018
dc.date.issued.fl_str_mv 2018
dc.date.accessioned.fl_str_mv 2023-07-13T23:55:23Z
dc.date.available.fl_str_mv 2023-07-13T23:55:23Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv ZAMITH-MIRANDA, D. et al. Fungal extracellular vesicles: modulating host–pathogen interactions by both the fungus and the host. Microbes and Infection, v. 20, n. 9-10, p. 501-501, 2018.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/59581
dc.identifier.issn.en_US.fl_str_mv 1286-4579
dc.identifier.doi.none.fl_str_mv 10.1016/J.MICINF.2018.01.011
dc.identifier.eissn.none.fl_str_mv 1769-714X
identifier_str_mv ZAMITH-MIRANDA, D. et al. Fungal extracellular vesicles: modulating host–pathogen interactions by both the fungus and the host. Microbes and Infection, v. 20, n. 9-10, p. 501-501, 2018.
1286-4579
10.1016/J.MICINF.2018.01.011
1769-714X
url https://www.arca.fiocruz.br/handle/icict/59581
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/59581/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/59581/2/10.1016_j.micinf.2018.01.011.pdf
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