Multilocus analysis of introgression between two sand fly vectors of leishmaniasis

Detalhes bibliográficos
Autor(a) principal: Mazzoni, Camila J.
Data de Publicação: 2008
Outros Autores: Araki, Alejandra S., Ferreira, Gabriel E. M., Azevedo, Renata V. D. M., Barbujani, Guido, Peixoto, Alexandre A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/32211
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Insetos. Rio de Janeiro, RJ, Brasil / University College Cork. Environmental Research Institute. Ireland.
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spelling Mazzoni, Camila J.Araki, Alejandra S.Ferreira, Gabriel E. M.Azevedo, Renata V. D. M.Barbujani, GuidoPeixoto, Alexandre A.2019-03-24T14:36:01Z2019-03-24T14:36:01Z2008MAZZONI, Camila J. et al. Multilocus analysis of introgression between two sand fly vectors of leishmaniasis. BMC Evolutionary Biology, v. 8, n. 141,p. 1-12, 2008.1471-2148https://www.arca.fiocruz.br/handle/icict/3221110.1186/1471-2148-8-141engBioMed CentralAnálise multicêntricaIntrogressãoLeishmanioseFlebetomíneosVetoresMultilocus analysisIntrogressionTwo sand fly vectorLeishmaniasisMultilocus analysis of introgression between two sand fly vectors of leishmaniasisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Insetos. Rio de Janeiro, RJ, Brasil / University College Cork. Environmental Research Institute. Ireland.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Insetos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Insetos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Insetos. Rio de Janeiro, RJ, Brasil / University of Leicester. Department of Genetics. Leicester, UK.Università di Ferrara. Dipartimento di Biologia. Ferrara, Italy.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Insetos. Rio de Janeiro, RJ, Brasil.Background: The phlebotomine sand flies (Diptera:Psychodidae) Lutzomyia (Nyssomyia) intermedia Lutz & Neiva 1912 and Lutzomyia (Nyssomyia) whitmani Antunes & Coutinho 1932 are two very closely related species and important vectors of American cutaneous leishmaniasis. Two singlelocus studies have revealed evidence for introgression between the two species in both mitochondrial and nuclear genomes. These findings have prompted the development of a multilocus approach to investigate in more detail the genetic exchanges between the two species. Results: We analyzed ten nuclear loci using the "isolation with migration" model implemented in the IM program, finding evidence for introgression from L. intermedia towards L. whitmani in three loci. These results confirm that introgression is occurring between the two species and suggest variation in the effects of gene flow among the different regions of the genome. Conclusion: The demonstration that these two vectors are not fully reproductively isolated might have important epidemiological consequences as these species could be exchanging genes controlling aspects of their vectorial capacity.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/32211/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALcamila_mazzoni_etal_IOC_2008.pdfcamila_mazzoni_etal_IOC_2008.pdfapplication/pdf632537https://www.arca.fiocruz.br/bitstream/icict/32211/2/camila_mazzoni_etal_IOC_2008.pdf03800b44a2883ff93ab0acd81077fce0MD52TEXTcamila_mazzoni_etal_IOC_2008.pdf.txtcamila_mazzoni_etal_IOC_2008.pdf.txtExtracted texttext/plain51253https://www.arca.fiocruz.br/bitstream/icict/32211/3/camila_mazzoni_etal_IOC_2008.pdf.txt80d99d0b04009619854f8a2b1617a9eeMD53icict/322112019-04-04 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dc.title.pt_BR.fl_str_mv Multilocus analysis of introgression between two sand fly vectors of leishmaniasis
title Multilocus analysis of introgression between two sand fly vectors of leishmaniasis
spellingShingle Multilocus analysis of introgression between two sand fly vectors of leishmaniasis
Mazzoni, Camila J.
Análise multicêntrica
Introgressão
Leishmaniose
Flebetomíneos
Vetores
Multilocus analysis
Introgression
Two sand fly vector
Leishmaniasis
title_short Multilocus analysis of introgression between two sand fly vectors of leishmaniasis
title_full Multilocus analysis of introgression between two sand fly vectors of leishmaniasis
title_fullStr Multilocus analysis of introgression between two sand fly vectors of leishmaniasis
title_full_unstemmed Multilocus analysis of introgression between two sand fly vectors of leishmaniasis
title_sort Multilocus analysis of introgression between two sand fly vectors of leishmaniasis
author Mazzoni, Camila J.
author_facet Mazzoni, Camila J.
Araki, Alejandra S.
Ferreira, Gabriel E. M.
Azevedo, Renata V. D. M.
Barbujani, Guido
Peixoto, Alexandre A.
author_role author
author2 Araki, Alejandra S.
Ferreira, Gabriel E. M.
Azevedo, Renata V. D. M.
Barbujani, Guido
Peixoto, Alexandre A.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Mazzoni, Camila J.
Araki, Alejandra S.
Ferreira, Gabriel E. M.
Azevedo, Renata V. D. M.
Barbujani, Guido
Peixoto, Alexandre A.
dc.subject.other.pt_BR.fl_str_mv Análise multicêntrica
Introgressão
Leishmaniose
Flebetomíneos
Vetores
topic Análise multicêntrica
Introgressão
Leishmaniose
Flebetomíneos
Vetores
Multilocus analysis
Introgression
Two sand fly vector
Leishmaniasis
dc.subject.en.pt_BR.fl_str_mv Multilocus analysis
Introgression
Two sand fly vector
Leishmaniasis
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Insetos. Rio de Janeiro, RJ, Brasil / University College Cork. Environmental Research Institute. Ireland.
publishDate 2008
dc.date.issued.fl_str_mv 2008
dc.date.accessioned.fl_str_mv 2019-03-24T14:36:01Z
dc.date.available.fl_str_mv 2019-03-24T14:36:01Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv MAZZONI, Camila J. et al. Multilocus analysis of introgression between two sand fly vectors of leishmaniasis. BMC Evolutionary Biology, v. 8, n. 141,p. 1-12, 2008.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/32211
dc.identifier.issn.pt_BR.fl_str_mv 1471-2148
dc.identifier.doi.none.fl_str_mv 10.1186/1471-2148-8-141
identifier_str_mv MAZZONI, Camila J. et al. Multilocus analysis of introgression between two sand fly vectors of leishmaniasis. BMC Evolutionary Biology, v. 8, n. 141,p. 1-12, 2008.
1471-2148
10.1186/1471-2148-8-141
url https://www.arca.fiocruz.br/handle/icict/32211
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/32211/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/32211/2/camila_mazzoni_etal_IOC_2008.pdf
https://www.arca.fiocruz.br/bitstream/icict/32211/3/camila_mazzoni_etal_IOC_2008.pdf.txt
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