Generalized Edema and Pseudothrombocytopenia After ChAdOx1 nCoV-19 COVID-19 Vaccination: A Case Report

Detalhes bibliográficos
Autor(a) principal: Bokel, Joanna
Data de Publicação: 2022
Outros Autores: Almeida, Daniela P. Mendes de, Gonçalves, Remy Martins, Palhinha, Lohanna, Vizzoni, Alexandre G., Correa, Danusa Ferreira, Brandão, Luciana Gomes Pedro, Bozza, Patrícia T., Grinsztejn, Beatriz
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/53283
Resumo: Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Departamento de Hematologia. Rio de Janeiro, RJ, Brasil / Clínica São Vicente. Unidade de Onco-Hematologia. Rio de Janeiro, RJ, Brasil.
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spelling Bokel, JoannaAlmeida, Daniela P. Mendes deGonçalves, Remy MartinsPalhinha, LohannaVizzoni, Alexandre G.Correa, Danusa FerreiraBrandão, Luciana Gomes PedroBozza, Patrícia T.Grinsztejn, Beatriz2022-06-15T19:10:07Z2022-06-15T19:10:07Z2022BOKEL, Joanna et al. Generalized Edema and Pseudothrombocytopenia After ChAdOx1 nCoV-19 COVID-19 Vaccination: A Case Report. Frontiers in Public Health, v. 10, Article 907652, p. 1-5, May 2022.2296-2565https://www.arca.fiocruz.br/handle/icict/5328310.3389/fpubh.2022.907652engFrontiers MediaEdema generalizadoPseudotrombocitopeniaTrombocitopenia espúriaSegurança da vacinaPseudotrombocitopenia induzida por vacinaCOVID-19Generalized edemaPseudothrombocytopeniaSpurious thrombocytopeniaVaccine safetyVaccine-induced pseudothrombocytopeniaCOVID-19Generalized Edema and Pseudothrombocytopenia After ChAdOx1 nCoV-19 COVID-19 Vaccination: A Case Reportinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Departamento de Hematologia. Rio de Janeiro, RJ, Brasil / Clínica São Vicente. Unidade de Onco-Hematologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Departamento de Hematologia. Rio de Janeiro, RJ, Brasil / Instituto Nacional do Câncer. Centro de Pesquisa. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Departamento de Hematologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Unidade de Pesquisa em Vigilância Sanitária e Imunização. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Unidade de Pesquisa em Vigilância Sanitária e Imunização. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil.Reports of side effects of vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are increasing worldwide. Capillary leak syndrome and vaccine-induced immune thrombotic thrombocytopenia are very rare but life-threatening adverse events that should be identified early and treated. However, isolated thrombocytopenia can indicate pseudothrombocytopenia. In certain people, ethylenediaminetetraacetic acid (EDTA) induces an in vitro platelet aggregation, resulting in misleading underestimation of platelet counts. It is essential to recognize pseudothrombocytopenia to prevent diagnostic errors, overtreatment, anxiety, and unnecessary invasive procedures.We present a case who developed generalized edema and persistent pseudothrombocytopenia after the first dose of the ChAdOx1 nCoV-19 vaccine (AstraZeneca).info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/53283/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALRemyGonçalves_PatriciaBozza_etal_IOC_2022.pdfRemyGonçalves_PatriciaBozza_etal_IOC_2022.pdfapplication/pdf965195https://www.arca.fiocruz.br/bitstream/icict/53283/2/RemyGon%c3%a7alves_PatriciaBozza_etal_IOC_2022.pdf8881d9149ec3d7daaef1b40991e96498MD52icict/532832023-02-15 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dc.title.pt_BR.fl_str_mv Generalized Edema and Pseudothrombocytopenia After ChAdOx1 nCoV-19 COVID-19 Vaccination: A Case Report
title Generalized Edema and Pseudothrombocytopenia After ChAdOx1 nCoV-19 COVID-19 Vaccination: A Case Report
spellingShingle Generalized Edema and Pseudothrombocytopenia After ChAdOx1 nCoV-19 COVID-19 Vaccination: A Case Report
Bokel, Joanna
Edema generalizado
Pseudotrombocitopenia
Trombocitopenia espúria
Segurança da vacina
Pseudotrombocitopenia induzida por vacina
COVID-19
Generalized edema
Pseudothrombocytopenia
Spurious thrombocytopenia
Vaccine safety
Vaccine-induced pseudothrombocytopenia
COVID-19
title_short Generalized Edema and Pseudothrombocytopenia After ChAdOx1 nCoV-19 COVID-19 Vaccination: A Case Report
title_full Generalized Edema and Pseudothrombocytopenia After ChAdOx1 nCoV-19 COVID-19 Vaccination: A Case Report
title_fullStr Generalized Edema and Pseudothrombocytopenia After ChAdOx1 nCoV-19 COVID-19 Vaccination: A Case Report
title_full_unstemmed Generalized Edema and Pseudothrombocytopenia After ChAdOx1 nCoV-19 COVID-19 Vaccination: A Case Report
title_sort Generalized Edema and Pseudothrombocytopenia After ChAdOx1 nCoV-19 COVID-19 Vaccination: A Case Report
author Bokel, Joanna
author_facet Bokel, Joanna
Almeida, Daniela P. Mendes de
Gonçalves, Remy Martins
Palhinha, Lohanna
Vizzoni, Alexandre G.
Correa, Danusa Ferreira
Brandão, Luciana Gomes Pedro
Bozza, Patrícia T.
Grinsztejn, Beatriz
author_role author
author2 Almeida, Daniela P. Mendes de
Gonçalves, Remy Martins
Palhinha, Lohanna
Vizzoni, Alexandre G.
Correa, Danusa Ferreira
Brandão, Luciana Gomes Pedro
Bozza, Patrícia T.
Grinsztejn, Beatriz
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Bokel, Joanna
Almeida, Daniela P. Mendes de
Gonçalves, Remy Martins
Palhinha, Lohanna
Vizzoni, Alexandre G.
Correa, Danusa Ferreira
Brandão, Luciana Gomes Pedro
Bozza, Patrícia T.
Grinsztejn, Beatriz
dc.subject.other.pt_BR.fl_str_mv Edema generalizado
Pseudotrombocitopenia
Trombocitopenia espúria
Segurança da vacina
Pseudotrombocitopenia induzida por vacina
topic Edema generalizado
Pseudotrombocitopenia
Trombocitopenia espúria
Segurança da vacina
Pseudotrombocitopenia induzida por vacina
COVID-19
Generalized edema
Pseudothrombocytopenia
Spurious thrombocytopenia
Vaccine safety
Vaccine-induced pseudothrombocytopenia
COVID-19
dc.subject.other.none.fl_str_mv COVID-19
dc.subject.en.pt_BR.fl_str_mv Generalized edema
Pseudothrombocytopenia
Spurious thrombocytopenia
Vaccine safety
Vaccine-induced pseudothrombocytopenia
dc.subject.en.none.fl_str_mv COVID-19
description Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Departamento de Hematologia. Rio de Janeiro, RJ, Brasil / Clínica São Vicente. Unidade de Onco-Hematologia. Rio de Janeiro, RJ, Brasil.
publishDate 2022
dc.date.accessioned.fl_str_mv 2022-06-15T19:10:07Z
dc.date.available.fl_str_mv 2022-06-15T19:10:07Z
dc.date.issued.fl_str_mv 2022
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv BOKEL, Joanna et al. Generalized Edema and Pseudothrombocytopenia After ChAdOx1 nCoV-19 COVID-19 Vaccination: A Case Report. Frontiers in Public Health, v. 10, Article 907652, p. 1-5, May 2022.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/53283
dc.identifier.issn.pt_BR.fl_str_mv 2296-2565
dc.identifier.doi.none.fl_str_mv 10.3389/fpubh.2022.907652
identifier_str_mv BOKEL, Joanna et al. Generalized Edema and Pseudothrombocytopenia After ChAdOx1 nCoV-19 COVID-19 Vaccination: A Case Report. Frontiers in Public Health, v. 10, Article 907652, p. 1-5, May 2022.
2296-2565
10.3389/fpubh.2022.907652
url https://www.arca.fiocruz.br/handle/icict/53283
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Frontiers Media
publisher.none.fl_str_mv Frontiers Media
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/53283/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/53283/2/RemyGon%c3%a7alves_PatriciaBozza_etal_IOC_2022.pdf
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repository.mail.fl_str_mv repositorio.arca@fiocruz.br
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