BDE-99 (2,2′,4,4′,5 - pentain polybrominated diphenyl ether) induces toxic effects in Oreochromis niloticus after sub-chronic and oral exposure

Detalhes bibliográficos
Autor(a) principal: Leão-Buchir, Joelma
Data de Publicação: 2023
Outros Autores: Souza, Tugstênio Lima de, Souza, Claudemir de, Fávaro, Luís Fernando, Brito, Patrícia Manuitt, Carneiro, Milena Carvalho, Marcon, Bruna Hilzendeger, Esquivel, Luíse, Ribeiro, Ciro Alberto de Oliveira, Prodocimo, Maritana Mela
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/57170
Resumo: Universidade Federal do Paraná. Departamento de Biologia Celular. Curitiba, PR, Brasil. / Departamento de Toxicologia Molecular e Ambiente. Centro de Biotecnologia. Universidade Eduardo Mondlane. Maputo, Mozambique.
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spelling Leão-Buchir, JoelmaSouza, Tugstênio Lima deSouza, Claudemir deFávaro, Luís FernandoBrito, Patrícia ManuittCarneiro, Milena CarvalhoMarcon, Bruna HilzendegerEsquivel, LuíseRibeiro, Ciro Alberto de OliveiraProdocimo, Maritana Mela2023-03-02T11:41:02Z2023-03-02T11:41:02Z2023LEÃO-BUCHIR, Joelma et al. BDE-99 (2,2′,4,4′,5 - pentain polybrominated diphenyl ether) induces toxic effects in Oreochromis niloticus after sub-chronic and oral exposure. Environmental Toxicology and Pharmacology, v. 97, p. 1–15, 2023.1872-7077https://www.arca.fiocruz.br/handle/icict/5717010.1016/j.etap.2022.104034porElsevierBDE-99 (2,2′,4,4′,5 - pentain polybrominated diphenyl ether) induces toxic effects in Oreochromis niloticus after sub-chronic and oral exposureinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal do Paraná. Departamento de Biologia Celular. Curitiba, PR, Brasil. / Departamento de Toxicologia Molecular e Ambiente. Centro de Biotecnologia. Universidade Eduardo Mondlane. Maputo, Mozambique.Universidade Federal do Paraná. Departamento de Biologia Celular. Curitiba, PR, Brasil.Universidade Federal do Paraná. Departamento de Biologia Celular. Curitiba, PR, Brasil.Universidade Federal do Paraná. Departamento de Biologia Celular. Curitiba, PR, Brasil.Universidade Federal do Paraná. Departamento de Biologia Celular. Curitiba, PR, Brasil.Universidade de São Paulo. Instituto de Ciências Biomédicas. Departamento de Imunologia. São Paulo, SP, Brasil.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil.Estação de Piscicultura Panamá. Paulo Lopes, Brasil.Universidade Federal do Paraná. Departamento de Biologia Celular. Curitiba, PR, Brasil.Universidade Federal do Paraná. Departamento de Biologia Celular. Curitiba, PR, Brasil.PBDEs are toxic, lipophilic, hydrophobic, and persistent artificial chemicals, characterized by high physical and chemical stability. Although PBDEs are known to disturb hormone signaling, many effects of 2,2′ ,4,4′ ,5 - pentain polybrominated diphenyl ethers (BDE-99) in fish remain unclear. The current study investigates the effects of BDE-99 in Oreochromis niloticus where sixty-four juvenile fish were orally exposed to 0.294, 2.94, 29.4 ng g 1 of BDE-99, every 10 days, during 80 days. The results showed histopathological findings in liver and kidney, increasing acetylcholinesterase activity in muscle, disturbs in the antioxidant system in liver and brain and decreasing the plasmatic levels of vitellogenin in females. According to multivariate analysis (IBR), the higher doses are related to the interaction of oxidative and non-oxidative enzymes. The present study provided evidence of deleterious effects after sub-chronic exposure of BDE 99 to O. niloticus, increasing the knowledge about its risk of exposure in fish.Water QualityBiomarkersPolybrominated Diphenyl EthersBrominated Flame RetardantsFresh WaterTilapiaCalidad del AguaÉteres Difenilos HalogenadosAgua DulceQualité de l'eauMarqueurs biologiquesÉthers de polyhalogénophényleEau douceQualidade da ÁguaBiomarcadoresÉteres Difenil HalogenadosÁgua DoceTilápiainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; 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dc.title.en_US.fl_str_mv BDE-99 (2,2′,4,4′,5 - pentain polybrominated diphenyl ether) induces toxic effects in Oreochromis niloticus after sub-chronic and oral exposure
title BDE-99 (2,2′,4,4′,5 - pentain polybrominated diphenyl ether) induces toxic effects in Oreochromis niloticus after sub-chronic and oral exposure
spellingShingle BDE-99 (2,2′,4,4′,5 - pentain polybrominated diphenyl ether) induces toxic effects in Oreochromis niloticus after sub-chronic and oral exposure
Leão-Buchir, Joelma
Water Quality
Biomarkers
Polybrominated Diphenyl Ethers
Brominated Flame Retardants
Fresh Water
Tilapia
Calidad del Agua
Éteres Difenilos Halogenados
Agua Dulce
Qualité de l'eau
Marqueurs biologiques
Éthers de polyhalogénophényle
Eau douce
Qualidade da Água
Biomarcadores
Éteres Difenil Halogenados
Água Doce
Tilápia
title_short BDE-99 (2,2′,4,4′,5 - pentain polybrominated diphenyl ether) induces toxic effects in Oreochromis niloticus after sub-chronic and oral exposure
title_full BDE-99 (2,2′,4,4′,5 - pentain polybrominated diphenyl ether) induces toxic effects in Oreochromis niloticus after sub-chronic and oral exposure
title_fullStr BDE-99 (2,2′,4,4′,5 - pentain polybrominated diphenyl ether) induces toxic effects in Oreochromis niloticus after sub-chronic and oral exposure
title_full_unstemmed BDE-99 (2,2′,4,4′,5 - pentain polybrominated diphenyl ether) induces toxic effects in Oreochromis niloticus after sub-chronic and oral exposure
title_sort BDE-99 (2,2′,4,4′,5 - pentain polybrominated diphenyl ether) induces toxic effects in Oreochromis niloticus after sub-chronic and oral exposure
author Leão-Buchir, Joelma
author_facet Leão-Buchir, Joelma
Souza, Tugstênio Lima de
Souza, Claudemir de
Fávaro, Luís Fernando
Brito, Patrícia Manuitt
Carneiro, Milena Carvalho
Marcon, Bruna Hilzendeger
Esquivel, Luíse
Ribeiro, Ciro Alberto de Oliveira
Prodocimo, Maritana Mela
author_role author
author2 Souza, Tugstênio Lima de
Souza, Claudemir de
Fávaro, Luís Fernando
Brito, Patrícia Manuitt
Carneiro, Milena Carvalho
Marcon, Bruna Hilzendeger
Esquivel, Luíse
Ribeiro, Ciro Alberto de Oliveira
Prodocimo, Maritana Mela
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Leão-Buchir, Joelma
Souza, Tugstênio Lima de
Souza, Claudemir de
Fávaro, Luís Fernando
Brito, Patrícia Manuitt
Carneiro, Milena Carvalho
Marcon, Bruna Hilzendeger
Esquivel, Luíse
Ribeiro, Ciro Alberto de Oliveira
Prodocimo, Maritana Mela
dc.subject.en.en_US.fl_str_mv Water Quality
Biomarkers
Polybrominated Diphenyl Ethers
Brominated Flame Retardants
Fresh Water
Tilapia
topic Water Quality
Biomarkers
Polybrominated Diphenyl Ethers
Brominated Flame Retardants
Fresh Water
Tilapia
Calidad del Agua
Éteres Difenilos Halogenados
Agua Dulce
Qualité de l'eau
Marqueurs biologiques
Éthers de polyhalogénophényle
Eau douce
Qualidade da Água
Biomarcadores
Éteres Difenil Halogenados
Água Doce
Tilápia
dc.subject.es.en_US.fl_str_mv Calidad del Agua
Éteres Difenilos Halogenados
Agua Dulce
dc.subject.fr.en_US.fl_str_mv Qualité de l'eau
Marqueurs biologiques
Éthers de polyhalogénophényle
Eau douce
dc.subject.decs.en_US.fl_str_mv Qualidade da Água
Biomarcadores
Éteres Difenil Halogenados
Água Doce
Tilápia
description Universidade Federal do Paraná. Departamento de Biologia Celular. Curitiba, PR, Brasil. / Departamento de Toxicologia Molecular e Ambiente. Centro de Biotecnologia. Universidade Eduardo Mondlane. Maputo, Mozambique.
publishDate 2023
dc.date.accessioned.fl_str_mv 2023-03-02T11:41:02Z
dc.date.available.fl_str_mv 2023-03-02T11:41:02Z
dc.date.issued.fl_str_mv 2023
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv LEÃO-BUCHIR, Joelma et al. BDE-99 (2,2′,4,4′,5 - pentain polybrominated diphenyl ether) induces toxic effects in Oreochromis niloticus after sub-chronic and oral exposure. Environmental Toxicology and Pharmacology, v. 97, p. 1–15, 2023.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/57170
dc.identifier.issn.en_US.fl_str_mv 1872-7077
dc.identifier.doi.none.fl_str_mv 10.1016/j.etap.2022.104034
identifier_str_mv LEÃO-BUCHIR, Joelma et al. BDE-99 (2,2′,4,4′,5 - pentain polybrominated diphenyl ether) induces toxic effects in Oreochromis niloticus after sub-chronic and oral exposure. Environmental Toxicology and Pharmacology, v. 97, p. 1–15, 2023.
1872-7077
10.1016/j.etap.2022.104034
url https://www.arca.fiocruz.br/handle/icict/57170
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/57170/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/57170/2/1-s2.0-S1382668922002277-mainok.pdf
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
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