Decrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7

Detalhes bibliográficos
Autor(a) principal: Mello, Cíntia da Silva
Data de Publicação: 2017
Outros Autores: Valente, Ligia Maria Marino, Wolff, Thiago, Lima Junior, Raimundo Sousa, Fialho, Luciana Gomes, Marinho, Cintia Ferreira, Azeredo, Elzinandes Leal, Pinto, Luzia Maria Oliveira, Pereira, Rita de Cássia Alves, Siani, Antonio Carlos, Kubelka, Claire Fernandes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/24799
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Viral. Rio de Janeiro, RJ, Brasil.
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spelling Mello, Cíntia da SilvaValente, Ligia Maria MarinoWolff, ThiagoLima Junior, Raimundo SousaFialho, Luciana GomesMarinho, Cintia FerreiraAzeredo, Elzinandes LealPinto, Luzia Maria OliveiraPereira, Rita de Cássia AlvesSiani, Antonio CarlosKubelka, Claire Fernandes2018-02-11T12:46:26Z2018-02-11T12:46:26Z2017MELLO, Cíntia da Silva; et al. Decrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7. Mem Inst Oswaldo Cruz, v.112, n.6, p.458-468, June 2017.0074-0276https://www.arca.fiocruz.br/handle/icict/2479910.1590/0074-027601603231678-8060engFundação Oswaldo Cruz. Instituto Oswaldo Cruz.DengueUncaria guianensisMedicina tradicionalImunomodulaçãoAntiviraiskaempferitrinDengueUncaria guianensistraditional medicineimmunomodulationantiviralskaempferitrinDecrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Viral. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Instituto de Química. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Instituto de Química. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Viral. Rio de Janeiro, RJ, Brasil / Universidade do Estado do Amazonas. Escola Normal Superior. Manaus, Am, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Viral. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Viral. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Viral. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Viral. Rio de Janeiro, RJ, Brasil.Embrapa Agroindústria Tropical. Fortaleza, CE, Brasil.Fundação Oswaldo Cruz. Instituto de Tecnologia em Fármacos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Viral. Rio de Janeiro, RJ, Brasil.Dengue fever may present hemorrhages and cavitary effusions as result of exacerbated immune responses. We investigated hydro-alcoholic extracts from leaves (UGL) and bark (UGB) of the medicinal species Uncaria guinanensis with respect to antiviral effects in Dengue virus (DENV) infection and in immunological parameters associated with in vivo physiopathological features.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/24799/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALcintiasilva_melo_etal_IOC_2017.pdfcintiasilva_melo_etal_IOC_2017.pdfapplication/pdf2999377https://www.arca.fiocruz.br/bitstream/icict/24799/2/cintiasilva_melo_etal_IOC_2017.pdf694c8a639e979dd7ee437fe2a8c9cf99MD52TEXTcintiasilva_melo_etal_IOC_2017.pdf.txtcintiasilva_melo_etal_IOC_2017.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Decrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7
title Decrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7
spellingShingle Decrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7
Mello, Cíntia da Silva
Dengue
Uncaria guianensis
Medicina tradicional
Imunomodulação
Antivirais
kaempferitrin
Dengue
Uncaria guianensis
traditional medicine
immunomodulation
antivirals
kaempferitrin
title_short Decrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7
title_full Decrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7
title_fullStr Decrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7
title_full_unstemmed Decrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7
title_sort Decrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7
author Mello, Cíntia da Silva
author_facet Mello, Cíntia da Silva
Valente, Ligia Maria Marino
Wolff, Thiago
Lima Junior, Raimundo Sousa
Fialho, Luciana Gomes
Marinho, Cintia Ferreira
Azeredo, Elzinandes Leal
Pinto, Luzia Maria Oliveira
Pereira, Rita de Cássia Alves
Siani, Antonio Carlos
Kubelka, Claire Fernandes
author_role author
author2 Valente, Ligia Maria Marino
Wolff, Thiago
Lima Junior, Raimundo Sousa
Fialho, Luciana Gomes
Marinho, Cintia Ferreira
Azeredo, Elzinandes Leal
Pinto, Luzia Maria Oliveira
Pereira, Rita de Cássia Alves
Siani, Antonio Carlos
Kubelka, Claire Fernandes
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Mello, Cíntia da Silva
Valente, Ligia Maria Marino
Wolff, Thiago
Lima Junior, Raimundo Sousa
Fialho, Luciana Gomes
Marinho, Cintia Ferreira
Azeredo, Elzinandes Leal
Pinto, Luzia Maria Oliveira
Pereira, Rita de Cássia Alves
Siani, Antonio Carlos
Kubelka, Claire Fernandes
dc.subject.other.pt_BR.fl_str_mv Dengue
Uncaria guianensis
Medicina tradicional
Imunomodulação
Antivirais
kaempferitrin
topic Dengue
Uncaria guianensis
Medicina tradicional
Imunomodulação
Antivirais
kaempferitrin
Dengue
Uncaria guianensis
traditional medicine
immunomodulation
antivirals
kaempferitrin
dc.subject.en.pt_BR.fl_str_mv Dengue
Uncaria guianensis
traditional medicine
immunomodulation
antivirals
kaempferitrin
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Viral. Rio de Janeiro, RJ, Brasil.
publishDate 2017
dc.date.issued.fl_str_mv 2017
dc.date.accessioned.fl_str_mv 2018-02-11T12:46:26Z
dc.date.available.fl_str_mv 2018-02-11T12:46:26Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv MELLO, Cíntia da Silva; et al. Decrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7. Mem Inst Oswaldo Cruz, v.112, n.6, p.458-468, June 2017.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/24799
dc.identifier.issn.pt_BR.fl_str_mv 0074-0276
dc.identifier.doi.none.fl_str_mv 10.1590/0074-02760160323
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv MELLO, Cíntia da Silva; et al. Decrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7. Mem Inst Oswaldo Cruz, v.112, n.6, p.458-468, June 2017.
0074-0276
10.1590/0074-02760160323
1678-8060
url https://www.arca.fiocruz.br/handle/icict/24799
dc.language.iso.fl_str_mv eng
language eng
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dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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