Decrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
DOI: | 10.1590/0074-02760160323 |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/24799 |
Resumo: | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Viral. Rio de Janeiro, RJ, Brasil. |
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Mello, Cíntia da SilvaValente, Ligia Maria MarinoWolff, ThiagoLima Junior, Raimundo SousaFialho, Luciana GomesMarinho, Cintia FerreiraAzeredo, Elzinandes LealPinto, Luzia Maria OliveiraPereira, Rita de Cássia AlvesSiani, Antonio CarlosKubelka, Claire Fernandes2018-02-11T12:46:26Z2018-02-11T12:46:26Z2017MELLO, Cíntia da Silva; et al. Decrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7. Mem Inst Oswaldo Cruz, v.112, n.6, p.458-468, June 2017.0074-0276https://www.arca.fiocruz.br/handle/icict/2479910.1590/0074-027601603231678-8060engFundação Oswaldo Cruz. Instituto Oswaldo Cruz.DengueUncaria guianensisMedicina tradicionalImunomodulaçãoAntiviraiskaempferitrinDengueUncaria guianensistraditional medicineimmunomodulationantiviralskaempferitrinDecrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Viral. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Instituto de Química. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Instituto de Química. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Viral. Rio de Janeiro, RJ, Brasil / Universidade do Estado do Amazonas. Escola Normal Superior. Manaus, Am, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Viral. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Viral. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Viral. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Viral. Rio de Janeiro, RJ, Brasil.Embrapa Agroindústria Tropical. Fortaleza, CE, Brasil.Fundação Oswaldo Cruz. Instituto de Tecnologia em Fármacos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Viral. Rio de Janeiro, RJ, Brasil.Dengue fever may present hemorrhages and cavitary effusions as result of exacerbated immune responses. We investigated hydro-alcoholic extracts from leaves (UGL) and bark (UGB) of the medicinal species Uncaria guinanensis with respect to antiviral effects in Dengue virus (DENV) infection and in immunological parameters associated with in vivo physiopathological features.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/24799/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALcintiasilva_melo_etal_IOC_2017.pdfcintiasilva_melo_etal_IOC_2017.pdfapplication/pdf2999377https://www.arca.fiocruz.br/bitstream/icict/24799/2/cintiasilva_melo_etal_IOC_2017.pdf694c8a639e979dd7ee437fe2a8c9cf99MD52TEXTcintiasilva_melo_etal_IOC_2017.pdf.txtcintiasilva_melo_etal_IOC_2017.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv |
Decrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7 |
title |
Decrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7 |
spellingShingle |
Decrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7 Mello, Cíntia da Silva Dengue Uncaria guianensis Medicina tradicional Imunomodulação Antivirais kaempferitrin Dengue Uncaria guianensis traditional medicine immunomodulation antivirals kaempferitrin |
title_short |
Decrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7 |
title_full |
Decrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7 |
title_fullStr |
Decrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7 |
title_full_unstemmed |
Decrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7 |
title_sort |
Decrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7 |
author |
Mello, Cíntia da Silva |
author_facet |
Mello, Cíntia da Silva Valente, Ligia Maria Marino Wolff, Thiago Lima Junior, Raimundo Sousa Fialho, Luciana Gomes Marinho, Cintia Ferreira Azeredo, Elzinandes Leal Pinto, Luzia Maria Oliveira Pereira, Rita de Cássia Alves Siani, Antonio Carlos Kubelka, Claire Fernandes |
author_role |
author |
author2 |
Valente, Ligia Maria Marino Wolff, Thiago Lima Junior, Raimundo Sousa Fialho, Luciana Gomes Marinho, Cintia Ferreira Azeredo, Elzinandes Leal Pinto, Luzia Maria Oliveira Pereira, Rita de Cássia Alves Siani, Antonio Carlos Kubelka, Claire Fernandes |
author2_role |
author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Mello, Cíntia da Silva Valente, Ligia Maria Marino Wolff, Thiago Lima Junior, Raimundo Sousa Fialho, Luciana Gomes Marinho, Cintia Ferreira Azeredo, Elzinandes Leal Pinto, Luzia Maria Oliveira Pereira, Rita de Cássia Alves Siani, Antonio Carlos Kubelka, Claire Fernandes |
dc.subject.other.pt_BR.fl_str_mv |
Dengue Uncaria guianensis Medicina tradicional Imunomodulação Antivirais kaempferitrin |
topic |
Dengue Uncaria guianensis Medicina tradicional Imunomodulação Antivirais kaempferitrin Dengue Uncaria guianensis traditional medicine immunomodulation antivirals kaempferitrin |
dc.subject.en.pt_BR.fl_str_mv |
Dengue Uncaria guianensis traditional medicine immunomodulation antivirals kaempferitrin |
description |
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Viral. Rio de Janeiro, RJ, Brasil. |
publishDate |
2017 |
dc.date.issued.fl_str_mv |
2017 |
dc.date.accessioned.fl_str_mv |
2018-02-11T12:46:26Z |
dc.date.available.fl_str_mv |
2018-02-11T12:46:26Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
MELLO, Cíntia da Silva; et al. Decrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7. Mem Inst Oswaldo Cruz, v.112, n.6, p.458-468, June 2017. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/24799 |
dc.identifier.issn.pt_BR.fl_str_mv |
0074-0276 |
dc.identifier.doi.none.fl_str_mv |
10.1590/0074-02760160323 |
dc.identifier.eissn.none.fl_str_mv |
1678-8060 |
identifier_str_mv |
MELLO, Cíntia da Silva; et al. Decrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7. Mem Inst Oswaldo Cruz, v.112, n.6, p.458-468, June 2017. 0074-0276 10.1590/0074-02760160323 1678-8060 |
url |
https://www.arca.fiocruz.br/handle/icict/24799 |
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eng |
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eng |
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openAccess |
dc.publisher.none.fl_str_mv |
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. |
publisher.none.fl_str_mv |
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. |
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