HIV rapid testing as a key strategy for prevention of mother-to-child transmission in Brazil

Detalhes bibliográficos
Autor(a) principal: Veloso, Valdiléa G.
Data de Publicação: 2010
Outros Autores: Bastos, Francisco Inácio Pinkusfeld Monteiro, Portela, Margareth Crisóstomo, Grinsztejn, Beatriz, João, Esau Custodio, Pilotto, Jose Henrique da Silva, Araújo, Ana Beatriz Busch, Santos, Breno Riegel, Fonseca, Rosana Campos da, Kreitchmann, Regis, Derrico, Monica, Friedman, Ruth Khalili, Morgado, Mariza Gonçalves, Saines, Karin Nielsen, Bryson, Yvonne J.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/17694
Resumo: Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa em DST/AIDS. Rio de Janeiro, RJ. Brasil.
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spelling Veloso, Valdiléa G.Bastos, Francisco Inácio Pinkusfeld MonteiroPortela, Margareth CrisóstomoGrinsztejn, BeatrizJoão, Esau CustodioPilotto, Jose Henrique da SilvaAraújo, Ana Beatriz BuschSantos, Breno RiegelFonseca, Rosana Campos daKreitchmann, RegisDerrico, MonicaFriedman, Ruth KhaliliMorgado, Mariza GonçalvesSaines, Karin NielsenBryson, Yvonne J.2017-02-07T14:18:39Z2017-02-07T14:18:39Z2010Veloso, Valdiléa G. et al. HIV rapid testing as a key strategy for prevention of mother-to-child transmission in Brazil. Rev Saúde Pública, v.44, n.5, p.803-11, 2010.0034-8910https://www.arca.fiocruz.br/handle/icict/176941518-8787engUniversidade de São PauloGestantesCuidados Pré-NataisSerodiagnósticoAmamentaçãoInfecções por HIVDiagnósticoTransmissão Vertical de Doenças InfecciosasSíndrome da Imunodeficiência AdquiridaPrevenção e controlePregnant WomenPrenatal CareBreast FeedingAIDS SerodiagnosisHIV Infections, diagnosisInfectious Disease Transmission, VerticalAcquired Immunodefi ciency Syndrome, prevention & controlHIV rapid testing as a key strategy for prevention of mother-to-child transmission in BrazilTeste rápido para o HIV como estratégia de prevenção da transmissão vertical no Brasilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa em DST/AIDS. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto de Comunicação e Informação Científica e Tecnológica em Saúde. Laboratório de Informação em Saúde. Rio de janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Departamento de Administração e Planejamento em Saúde. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa em DST/AIDS. Rio de Janeiro, RJ. Brasil.Hospital dos Servidores do Estado do Rio de Janeiro. Serviço de Doenças Infecciosas e Parasitárias. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa em DST/AIDS. Rio de Janeiro, RJ. Brasil.Secretaria Municipal de Saúde do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.Grupo Hospitalar Conceição. Hospital Nossa Senhora da Conceição. Departamento de Doenças Infecciosas. Porto Alegre, RS, Brasil.Hospital Fêmina. Porto Alegre, RS, Brasil.Irmandade da Santa Casa de Misericórdia de Porto Alegre. Porto Alegre, RS, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa em DST/AIDS. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa em DST/AIDS. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa em DST/AIDS. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ. Brasil.University of California. David Geffen School of Medicine. Department of Pediatrics. Los Angeles, CA, USA.University of California. David Geffen School of Medicine. Department of Pediatrics. Los Angeles, CA, USA.OBJECTIVE: To assess the feasibility of HIV rapid testing for pregnant women at maternity hospital admission and of subsequent interventions to reduce perinatal HIV transmission. METHODS: Study based on a convenience sample of women unaware of their HIV serostatus when they were admitted to delivery in public maternity hospitals in Rio de Janeiro and Porto Alegre, Brazil, between March 2000 and April 2002. Women were counseled and tested using the Determine HIV1/2 Rapid Test. HIV infection was confi rmed using the Brazilian algorithm for HIV infection diagnosis. In utero transmission of HIV was determined using HIVDNA- PCR. There were performed descriptive analyses of sociodemographic data, number of previous pregnancies and abortions, number of prenatal care visits, timing of HIV testing, HIV rapid test result, neonatal and mother-tochild transmission interventions, by city studied. RESULTS: HIV prevalence in women was 6.5% (N=1,439) in Porto Alegre and 1.3% (N=3.778) in Rio de Janeiro. In Porto Alegre most of women were tested during labor (88.7%), while in Rio de Janeiro most were tested in the postpartum (67.5%). One hundred and forty-four infants were born to 143 HIVinfected women. All newborns but one in each city received at least prophylaxis with oral zidovudine. It was possible to completely avoid newborn exposure to breast milk in 96.8% and 51.1% of the cases in Porto Alegre and Rio de Janeiro, respectively. Injectable intravenous zidovudine was administered during labor to 68.8% and 27.7% newborns in Porto Alegre and Rio de Janeiro, respectively. Among those from whom blood samples were collected within 48 hours of birth, in utero transmission of HIV was confi rmed in 4 cases in Rio de Janeiro (4/47) and 6 cases in Porto Alegre (6/79). CONCLUSIONS: The strategy proved feasible in maternity hospitals in Rio de Janeiro and Porto Alegre. Efforts must be taken to maximize HIV testing during labor. There is a need of strong social support to provide this population access to health care services after hospital discharge.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/17694/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALmariza3_morgado_etal_IOC_2010.pdfmariza3_morgado_etal_IOC_2010.pdfapplication/pdf172853https://www.arca.fiocruz.br/bitstream/icict/17694/2/mariza3_morgado_etal_IOC_2010.pdf06bf7618a47527026251cf2242b3ca33MD52TEXTmariza3_morgado_etal_IOC_2010.pdf.txtmariza3_morgado_etal_IOC_2010.pdf.txtExtracted texttext/plain36480https://www.arca.fiocruz.br/bitstream/icict/17694/3/mariza3_morgado_etal_IOC_2010.pdf.txt290663edab5f3828d6c458967dc3fa1aMD53icict/176942023-09-04 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dc.title.pt_BR.fl_str_mv HIV rapid testing as a key strategy for prevention of mother-to-child transmission in Brazil
dc.title.alternative.pt_BR.fl_str_mv Teste rápido para o HIV como estratégia de prevenção da transmissão vertical no Brasil
title HIV rapid testing as a key strategy for prevention of mother-to-child transmission in Brazil
spellingShingle HIV rapid testing as a key strategy for prevention of mother-to-child transmission in Brazil
Veloso, Valdiléa G.
Gestantes
Cuidados Pré-Natais
Serodiagnóstico
Amamentação
Infecções por HIV
Diagnóstico
Transmissão Vertical de Doenças Infecciosas
Síndrome da Imunodeficiência Adquirida
Prevenção e controle
Pregnant Women
Prenatal Care
Breast Feeding
AIDS Serodiagnosis
HIV Infections, diagnosis
Infectious Disease Transmission, Vertical
Acquired Immunodefi ciency Syndrome, prevention & control
title_short HIV rapid testing as a key strategy for prevention of mother-to-child transmission in Brazil
title_full HIV rapid testing as a key strategy for prevention of mother-to-child transmission in Brazil
title_fullStr HIV rapid testing as a key strategy for prevention of mother-to-child transmission in Brazil
title_full_unstemmed HIV rapid testing as a key strategy for prevention of mother-to-child transmission in Brazil
title_sort HIV rapid testing as a key strategy for prevention of mother-to-child transmission in Brazil
author Veloso, Valdiléa G.
author_facet Veloso, Valdiléa G.
Bastos, Francisco Inácio Pinkusfeld Monteiro
Portela, Margareth Crisóstomo
Grinsztejn, Beatriz
João, Esau Custodio
Pilotto, Jose Henrique da Silva
Araújo, Ana Beatriz Busch
Santos, Breno Riegel
Fonseca, Rosana Campos da
Kreitchmann, Regis
Derrico, Monica
Friedman, Ruth Khalili
Morgado, Mariza Gonçalves
Saines, Karin Nielsen
Bryson, Yvonne J.
author_role author
author2 Bastos, Francisco Inácio Pinkusfeld Monteiro
Portela, Margareth Crisóstomo
Grinsztejn, Beatriz
João, Esau Custodio
Pilotto, Jose Henrique da Silva
Araújo, Ana Beatriz Busch
Santos, Breno Riegel
Fonseca, Rosana Campos da
Kreitchmann, Regis
Derrico, Monica
Friedman, Ruth Khalili
Morgado, Mariza Gonçalves
Saines, Karin Nielsen
Bryson, Yvonne J.
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Veloso, Valdiléa G.
Bastos, Francisco Inácio Pinkusfeld Monteiro
Portela, Margareth Crisóstomo
Grinsztejn, Beatriz
João, Esau Custodio
Pilotto, Jose Henrique da Silva
Araújo, Ana Beatriz Busch
Santos, Breno Riegel
Fonseca, Rosana Campos da
Kreitchmann, Regis
Derrico, Monica
Friedman, Ruth Khalili
Morgado, Mariza Gonçalves
Saines, Karin Nielsen
Bryson, Yvonne J.
dc.subject.other.pt_BR.fl_str_mv Gestantes
Cuidados Pré-Natais
Serodiagnóstico
Amamentação
Infecções por HIV
Diagnóstico
Transmissão Vertical de Doenças Infecciosas
Síndrome da Imunodeficiência Adquirida
Prevenção e controle
topic Gestantes
Cuidados Pré-Natais
Serodiagnóstico
Amamentação
Infecções por HIV
Diagnóstico
Transmissão Vertical de Doenças Infecciosas
Síndrome da Imunodeficiência Adquirida
Prevenção e controle
Pregnant Women
Prenatal Care
Breast Feeding
AIDS Serodiagnosis
HIV Infections, diagnosis
Infectious Disease Transmission, Vertical
Acquired Immunodefi ciency Syndrome, prevention & control
dc.subject.en.pt_BR.fl_str_mv Pregnant Women
Prenatal Care
Breast Feeding
AIDS Serodiagnosis
HIV Infections, diagnosis
Infectious Disease Transmission, Vertical
Acquired Immunodefi ciency Syndrome, prevention & control
description Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa em DST/AIDS. Rio de Janeiro, RJ. Brasil.
publishDate 2010
dc.date.issued.fl_str_mv 2010
dc.date.accessioned.fl_str_mv 2017-02-07T14:18:39Z
dc.date.available.fl_str_mv 2017-02-07T14:18:39Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv Veloso, Valdiléa G. et al. HIV rapid testing as a key strategy for prevention of mother-to-child transmission in Brazil. Rev Saúde Pública, v.44, n.5, p.803-11, 2010.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/17694
dc.identifier.issn.pt_BR.fl_str_mv 0034-8910
dc.identifier.eissn.none.fl_str_mv 1518-8787
identifier_str_mv Veloso, Valdiléa G. et al. HIV rapid testing as a key strategy for prevention of mother-to-child transmission in Brazil. Rev Saúde Pública, v.44, n.5, p.803-11, 2010.
0034-8910
1518-8787
url https://www.arca.fiocruz.br/handle/icict/17694
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Universidade de São Paulo
publisher.none.fl_str_mv Universidade de São Paulo
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