IgE antibodies from schistosomiasis patients to recognize epitopes in potato apyrase
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/36584 |
Resumo: | Universidade Federal de Juiz de Fora. Instituto de Ciências Biológicas. Juiz de Fora, MG, Brasil. |
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Gusmão, Michélia Antônia do NascimentoEmídio, Nayara BragaMarconato, Danielle GomesFarani, Priscila Silva GrijóManiezzi, Luiz FelipeCoelho, Paulo Marcos ZechOliveira, Rodrigo Corrêa deVasconcelos, Eveline GomesPinto, Priscila de Faria2019-10-18T18:36:13Z2019-10-18T18:36:13Z2019GUSMAO, Michélia Antônia do Nascimento et al. IgE antibodies from schistosomiasis patients to recognize epitopes in potato apyrase. Revista da Sociedade Brasileira de Medicina Tropical, v. 52, p. 1-4, 2019.0037-8682https://www.arca.fiocruz.br/handle/icict/3658410.1590/0037-8682-0139-2018engSociedade Brasileira de Medicina TropicalIgE antibodies from schistosomiasis patients to recognize epitopes in potato apyraseinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal de Juiz de Fora. Instituto de Ciências Biológicas. Juiz de Fora, MG, Brasil.Universidade Federal de Juiz de Fora. Instituto de Ciências Biológicas. Juiz de Fora, MG, Brasil.Universidade Federal de Juiz de Fora. Instituto de Ciências Biológicas. Juiz de Fora, MG, Brasil.Universidade Federal de Juiz de Fora. Instituto de Ciências Biológicas. Juiz de Fora, MG, Brasil.Universidade Federal de Juiz de Fora. Instituto de Ciências Biológicas. Juiz de Fora, MG, Brasil.Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brasil.Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brasil.Universidade Federal de Juiz de Fora. Instituto de Ciências Biológicas. Juiz de Fora, MG, Brasil.Universidade Federal de Juiz de Fora. Instituto de Ciências Biológicas. Juiz de Fora, MG, Brasil.INTRODUCTION: High percentages of structural identity and cross-immunoreactivity have been reported between potato apyrase and Schistosoma mansoni ATP diphosphohydrolase (SmATPDases) isoforms, showing the existence of particular epitopes shared between these proteins. METHODS: Potato apyrase was employed using ELISA, western blot, and mouse immunization methods to verify IgE reactivity. RESULTS: Most of the schistosomiasis patient’s (75%) serum was seropositive for potato apyrase and this protein was recognized using western blotting, suggesting that parasite and plant proteins share IgE-binding epitopes. C57BL/6 mice immunized with potato apyrase showed increased IgE antibody production. CONCLUSIONS: Potato apyrase and SmATPDases have IgE-binding epitopes.ATP diphosphohydrolaseIgEPotato apyraseinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83082https://www.arca.fiocruz.br/bitstream/icict/36584/1/license.txt9193a7c197bc67acd023525e72a03240MD51ORIGINALIgE antibodies from schistosomiasis.pdfIgE antibodies from schistosomiasis.pdfapplication/pdf2652788https://www.arca.fiocruz.br/bitstream/icict/36584/2/IgE%20antibodies%20from%20schistosomiasis.pdfea77522d259cd327e1569ef43f5a7e81MD52TEXTIgE antibodies from schistosomiasis.pdf.txtIgE antibodies from schistosomiasis.pdf.txtExtracted texttext/plain195https://www.arca.fiocruz.br/bitstream/icict/36584/3/IgE%20antibodies%20from%20schistosomiasis.pdf.txt9b40aab7ce1b7828a2bcb07c0f250060MD53icict/365842019-11-07 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dc.title.pt_BR.fl_str_mv |
IgE antibodies from schistosomiasis patients to recognize epitopes in potato apyrase |
title |
IgE antibodies from schistosomiasis patients to recognize epitopes in potato apyrase |
spellingShingle |
IgE antibodies from schistosomiasis patients to recognize epitopes in potato apyrase Gusmão, Michélia Antônia do Nascimento ATP diphosphohydrolase IgE Potato apyrase |
title_short |
IgE antibodies from schistosomiasis patients to recognize epitopes in potato apyrase |
title_full |
IgE antibodies from schistosomiasis patients to recognize epitopes in potato apyrase |
title_fullStr |
IgE antibodies from schistosomiasis patients to recognize epitopes in potato apyrase |
title_full_unstemmed |
IgE antibodies from schistosomiasis patients to recognize epitopes in potato apyrase |
title_sort |
IgE antibodies from schistosomiasis patients to recognize epitopes in potato apyrase |
author |
Gusmão, Michélia Antônia do Nascimento |
author_facet |
Gusmão, Michélia Antônia do Nascimento Emídio, Nayara Braga Marconato, Danielle Gomes Farani, Priscila Silva Grijó Maniezzi, Luiz Felipe Coelho, Paulo Marcos Zech Oliveira, Rodrigo Corrêa de Vasconcelos, Eveline Gomes Pinto, Priscila de Faria |
author_role |
author |
author2 |
Emídio, Nayara Braga Marconato, Danielle Gomes Farani, Priscila Silva Grijó Maniezzi, Luiz Felipe Coelho, Paulo Marcos Zech Oliveira, Rodrigo Corrêa de Vasconcelos, Eveline Gomes Pinto, Priscila de Faria |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Gusmão, Michélia Antônia do Nascimento Emídio, Nayara Braga Marconato, Danielle Gomes Farani, Priscila Silva Grijó Maniezzi, Luiz Felipe Coelho, Paulo Marcos Zech Oliveira, Rodrigo Corrêa de Vasconcelos, Eveline Gomes Pinto, Priscila de Faria |
dc.subject.en.pt_BR.fl_str_mv |
ATP diphosphohydrolase IgE Potato apyrase |
topic |
ATP diphosphohydrolase IgE Potato apyrase |
description |
Universidade Federal de Juiz de Fora. Instituto de Ciências Biológicas. Juiz de Fora, MG, Brasil. |
publishDate |
2019 |
dc.date.accessioned.fl_str_mv |
2019-10-18T18:36:13Z |
dc.date.available.fl_str_mv |
2019-10-18T18:36:13Z |
dc.date.issued.fl_str_mv |
2019 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
GUSMAO, Michélia Antônia do Nascimento et al. IgE antibodies from schistosomiasis patients to recognize epitopes in potato apyrase. Revista da Sociedade Brasileira de Medicina Tropical, v. 52, p. 1-4, 2019. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/36584 |
dc.identifier.issn.pt_BR.fl_str_mv |
0037-8682 |
dc.identifier.doi.none.fl_str_mv |
10.1590/0037-8682-0139-2018 |
identifier_str_mv |
GUSMAO, Michélia Antônia do Nascimento et al. IgE antibodies from schistosomiasis patients to recognize epitopes in potato apyrase. Revista da Sociedade Brasileira de Medicina Tropical, v. 52, p. 1-4, 2019. 0037-8682 10.1590/0037-8682-0139-2018 |
url |
https://www.arca.fiocruz.br/handle/icict/36584 |
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eng |
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eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
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openAccess |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Medicina Tropical |
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Sociedade Brasileira de Medicina Tropical |
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