Quadrivalent HPV vaccine efficacy against disease related to vaccine and non-vaccine HPV types in males.

Detalhes bibliográficos
Autor(a) principal: Goldstone, Stephen
Data de Publicação: 2013
Outros Autores: Jessen, Heiko, Palefsky, Joel M, Giuliano, Anna R, Moreira Júnior, Edson Duarte, Vardas, Eftyhia, Aranda, Carlos, Hillman, Richard J, Ferris, Daron G, Coutlee, Francois, Marshall, J. Brooke, Vuocolo, Scott, Haupt, Richard M, Guris, Dalya, Garner, Elizabeth I. O
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/8716
Resumo: GarnerlaIcahn School of Medicine at Mount Sinai. New York, NY
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spelling Goldstone, StephenJessen, HeikoPalefsky, Joel MGiuliano, Anna RMoreira Júnior, Edson DuarteVardas, EftyhiaAranda, CarlosHillman, Richard JFerris, Daron GCoutlee, FrancoisMarshall, J. BrookeVuocolo, ScottHaupt, Richard MGuris, DalyaGarner, Elizabeth I. O2014-11-04T18:49:21Z2014-11-04T18:49:21Z2013GOLDSTONE, S. E. et al. Quadrivalent HPV vaccine efficacy against disease related to vaccine and non-vaccine HPV types in males. Vaccine, v. 31, n. 37, p. 3849-3855, 2013.1873-2518https://www.arca.fiocruz.br/handle/icict/8716dx.doi.org/10.1016/j.vaccine.2013.06.057engElsevier LtdQuadrivalent HPV vaccine efficacy against disease related to vaccine and non-vaccine HPV types in males.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleGarnerlaIcahn School of Medicine at Mount Sinai. New York, NYJ2: Private Clinic for Infectious Diseases. Berlin, GermanyUniversity of California San Francisco. Department of Medicine. San Francisco, CA, USARisk Assessment, Detection, and Intervention Program. H. Lee Moffitt Cancer Center and Research Institute. Tampa, FL, USAAssociação Obras Sociais Irmã Dulce. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, BrasilUniversity of Stellenbosch. Division of Medical Virology. Tygerberg, South Africa / Lancet Laboratories. Johannesburg, South AfricahUniversity Medical Center. National Public Health Institute. Morelos, MexicoWestern Sydney Sexual Health Center. Sydney, AustraliaGynecologic Cancer Prevention Center. Georgia Health Sciences University. Augusta, GA, USAUniversité de Montréal. Centre de Recherche du CHUM. Montréal, Quebec, CanadaMerck & Co. North Wales, PA, USAMerck & Co. North Wales, PA, USAMerck & Co. North Wales, PA, USAA small number of HPV types are related to a majority of HPV-related neoplastic lesions in humans. High-risk types such as HPV 16 and 18 are most often implicated, although other oncogenic and non-oncogenic HPV types can cause disease in men. The efficacy of the quadrivalent HPV vaccine (qHPV) against external genital lesions and intra-anal disease related to HPV in men has been demonstrated. This report examines the vaccine's efficacy against disease due to 10 additional non-vaccine HPV types, as well as efficacy regardless of HPV detection. The data presented suggest that vaccinating males against HPV 6, 11, 16 and 18 protects them against most vaccine HPV-type related anogenital disease. However, significant efficacy against disease due to non-vaccine HPV types was not seen. In addition, the data do not provide any evidence that vaccination with qHPV vaccine will increase the likelihood of disease caused by non-vaccine types in the short termHPVYoungMalesMen who have sex with menaNeoplasias do Ânus/virologiaInfecções por Papillomavirus/prevenção & controleInfecções por Papillomavirus/virologiaVacinas contra Papillomavirus/uso terapêuticoAdolescenteAdultoCanal Anal/patologiaNeoplasias do Ânus/epidemiologiaNeoplasias dos Genitais Masculinos/patologiaPapillomavirus Humano 11/patogenicidadePapillomavirus Humano 16/patogenicidadeHumanosMasculinoInfecções por Papillomavirus/epidemiologiaResultado do TratamentoAdulto Joveminfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://www.arca.fiocruz.br/bitstream/icict/8716/1/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD51ORIGINALGoldstone SE Quadrivalent....pdfGoldstone SE Quadrivalent....pdfapplication/pdf688410https://www.arca.fiocruz.br/bitstream/icict/8716/2/Goldstone%20SE%20Quadrivalent....pdf4e46a6ef9c00eb3d518afe5dc8974e71MD52TEXTGoldstone SE Quadrivalent....pdf.txtGoldstone SE Quadrivalent....pdf.txtExtracted texttext/plain37933https://www.arca.fiocruz.br/bitstream/icict/8716/3/Goldstone%20SE%20Quadrivalent....pdf.txt79675928b517665991be121a398f5f81MD53icict/87162023-03-15 14:33:15.28oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:15Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Quadrivalent HPV vaccine efficacy against disease related to vaccine and non-vaccine HPV types in males.
title Quadrivalent HPV vaccine efficacy against disease related to vaccine and non-vaccine HPV types in males.
spellingShingle Quadrivalent HPV vaccine efficacy against disease related to vaccine and non-vaccine HPV types in males.
Goldstone, Stephen
HPV
Young
Males
Men who have sex with mena
Neoplasias do Ânus/virologia
Infecções por Papillomavirus/prevenção & controle
Infecções por Papillomavirus/virologia
Vacinas contra Papillomavirus/uso terapêutico
Adolescente
Adulto
Canal Anal/patologia
Neoplasias do Ânus/epidemiologia
Neoplasias dos Genitais Masculinos/patologia
Papillomavirus Humano 11/patogenicidade
Papillomavirus Humano 16/patogenicidade
Humanos
Masculino
Infecções por Papillomavirus/epidemiologia
Resultado do Tratamento
Adulto Jovem
title_short Quadrivalent HPV vaccine efficacy against disease related to vaccine and non-vaccine HPV types in males.
title_full Quadrivalent HPV vaccine efficacy against disease related to vaccine and non-vaccine HPV types in males.
title_fullStr Quadrivalent HPV vaccine efficacy against disease related to vaccine and non-vaccine HPV types in males.
title_full_unstemmed Quadrivalent HPV vaccine efficacy against disease related to vaccine and non-vaccine HPV types in males.
title_sort Quadrivalent HPV vaccine efficacy against disease related to vaccine and non-vaccine HPV types in males.
author Goldstone, Stephen
author_facet Goldstone, Stephen
Jessen, Heiko
Palefsky, Joel M
Giuliano, Anna R
Moreira Júnior, Edson Duarte
Vardas, Eftyhia
Aranda, Carlos
Hillman, Richard J
Ferris, Daron G
Coutlee, Francois
Marshall, J. Brooke
Vuocolo, Scott
Haupt, Richard M
Guris, Dalya
Garner, Elizabeth I. O
author_role author
author2 Jessen, Heiko
Palefsky, Joel M
Giuliano, Anna R
Moreira Júnior, Edson Duarte
Vardas, Eftyhia
Aranda, Carlos
Hillman, Richard J
Ferris, Daron G
Coutlee, Francois
Marshall, J. Brooke
Vuocolo, Scott
Haupt, Richard M
Guris, Dalya
Garner, Elizabeth I. O
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Goldstone, Stephen
Jessen, Heiko
Palefsky, Joel M
Giuliano, Anna R
Moreira Júnior, Edson Duarte
Vardas, Eftyhia
Aranda, Carlos
Hillman, Richard J
Ferris, Daron G
Coutlee, Francois
Marshall, J. Brooke
Vuocolo, Scott
Haupt, Richard M
Guris, Dalya
Garner, Elizabeth I. O
dc.subject.en.pt_BR.fl_str_mv HPV
Young
Males
Men who have sex with mena
topic HPV
Young
Males
Men who have sex with mena
Neoplasias do Ânus/virologia
Infecções por Papillomavirus/prevenção & controle
Infecções por Papillomavirus/virologia
Vacinas contra Papillomavirus/uso terapêutico
Adolescente
Adulto
Canal Anal/patologia
Neoplasias do Ânus/epidemiologia
Neoplasias dos Genitais Masculinos/patologia
Papillomavirus Humano 11/patogenicidade
Papillomavirus Humano 16/patogenicidade
Humanos
Masculino
Infecções por Papillomavirus/epidemiologia
Resultado do Tratamento
Adulto Jovem
dc.subject.decs.pt_BR.fl_str_mv Neoplasias do Ânus/virologia
Infecções por Papillomavirus/prevenção & controle
Infecções por Papillomavirus/virologia
Vacinas contra Papillomavirus/uso terapêutico
Adolescente
Adulto
Canal Anal/patologia
Neoplasias do Ânus/epidemiologia
Neoplasias dos Genitais Masculinos/patologia
Papillomavirus Humano 11/patogenicidade
Papillomavirus Humano 16/patogenicidade
Humanos
Masculino
Infecções por Papillomavirus/epidemiologia
Resultado do Tratamento
Adulto Jovem
description GarnerlaIcahn School of Medicine at Mount Sinai. New York, NY
publishDate 2013
dc.date.issued.fl_str_mv 2013
dc.date.accessioned.fl_str_mv 2014-11-04T18:49:21Z
dc.date.available.fl_str_mv 2014-11-04T18:49:21Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv GOLDSTONE, S. E. et al. Quadrivalent HPV vaccine efficacy against disease related to vaccine and non-vaccine HPV types in males. Vaccine, v. 31, n. 37, p. 3849-3855, 2013.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/8716
dc.identifier.issn.none.fl_str_mv 1873-2518
dc.identifier.doi.none.fl_str_mv dx.doi.org/10.1016/j.vaccine.2013.06.057
identifier_str_mv GOLDSTONE, S. E. et al. Quadrivalent HPV vaccine efficacy against disease related to vaccine and non-vaccine HPV types in males. Vaccine, v. 31, n. 37, p. 3849-3855, 2013.
1873-2518
dx.doi.org/10.1016/j.vaccine.2013.06.057
url https://www.arca.fiocruz.br/handle/icict/8716
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier Ltd
publisher.none.fl_str_mv Elsevier Ltd
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
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instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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