Neutralizing antibodies to Enterovirus 71 in Belém, Brazil

Detalhes bibliográficos
Autor(a) principal: Gomes, Maria de Lourdes C.
Data de Publicação: 2002
Outros Autores: Castro, Ceyla Maria O. de, Oliveira, Maria José C., Silva, Edson Elias da
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/37226
Resumo: Fundação Nacional de Saúde. Instituto Evandro Chagas. Seção de Virologia. Belém, PA, Brasil.
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spelling Gomes, Maria de Lourdes C.Castro, Ceyla Maria O. deOliveira, Maria José C.Silva, Edson Elias da2019-11-21T14:03:22Z2019-11-21T14:03:22Z2002GOMES, Maria de Lourdes C. et al. Neutralizing antibodies to Enterovirus 71 in Belém, Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 97, n. 1, p. 47-49, Jan. 2002.0074-0206https://www.arca.fiocruz.br/handle/icict/3722610.1590/S0074-027620020001000061678-8060engFundação Oswaldo Cruz. Instituto Oswaldo CruzEnterovirus 71Anticorpos neutralizantes para EV 71Estudo de soroepidemiologiaBelémBrasilEnterovirus 71Neutralizing antibodies to EV 71Seroepidemiology studyBelémBrazilNeutralizing antibodies to Enterovirus 71 in Belém, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Nacional de Saúde. Instituto Evandro Chagas. Seção de Virologia. Belém, PA, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fusam. Secretaria de Estado de Saúde. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Non-polio enteroviruses (Coxsackievirus A, Coxsackievirus B, Echovirus and EV 68-72) which belong to the enterovirus (EV) genus, Picornaviridae family, may be responsible for acute flaccid paralysis, aseptic meningitis, myocarditis, hepatitis, pleurodinia, neonatal sepsis, hand, foot and mouth disease (HFMD) even though 50-80% of infections are asymptomatic. EV 71 has been responsible for outbreaks and epidemics of HFMD and acute neurologic disease justifying its study in our country. The aim of this study was to detect neutralizing antibodies (NtAb) to EV 71 in individuals up to 15 years of age living in Belém, State of Pará, northern Brazil. Serum samples from 238 patients attending the Virology Sector of Evandro Chagas Institute in Belém, Brazil, were analyzed using microneutralization tests that included RD cells and BrCr strain. Overall 40.8% (97/238) of tested samples had NtAb to EV 71. Regarding the distribution per age group, 85.2% (92/108) of patients aged 0-3 years had no NtAb to this virus and 69.2% of those 12 to15 years of age were seropositive. These results confirm that EV 71 infection occurs in the city of Belém; and that a high rate of individuals in this study were infected aged 3 years and over and, when aged 15 years nearly 70% had EV 71 NtAb.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/37226/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALCeylaCastro_EdsonESilva_etal_IOC_2002.pdfCeylaCastro_EdsonESilva_etal_IOC_2002.pdfapplication/pdf52663https://www.arca.fiocruz.br/bitstream/icict/37226/2/CeylaCastro_EdsonESilva_etal_IOC_2002.pdf19a902c8f681f95ac0c80b6c27da4e29MD52TEXTCeylaCastro_EdsonESilva_etal_IOC_2002.pdf.txtCeylaCastro_EdsonESilva_etal_IOC_2002.pdf.txtExtracted 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dc.title.en.fl_str_mv Neutralizing antibodies to Enterovirus 71 in Belém, Brazil
title Neutralizing antibodies to Enterovirus 71 in Belém, Brazil
spellingShingle Neutralizing antibodies to Enterovirus 71 in Belém, Brazil
Gomes, Maria de Lourdes C.
Enterovirus 71
Anticorpos neutralizantes para EV 71
Estudo de soroepidemiologia
Belém
Brasil
Enterovirus 71
Neutralizing antibodies to EV 71
Seroepidemiology study
Belém
Brazil
title_short Neutralizing antibodies to Enterovirus 71 in Belém, Brazil
title_full Neutralizing antibodies to Enterovirus 71 in Belém, Brazil
title_fullStr Neutralizing antibodies to Enterovirus 71 in Belém, Brazil
title_full_unstemmed Neutralizing antibodies to Enterovirus 71 in Belém, Brazil
title_sort Neutralizing antibodies to Enterovirus 71 in Belém, Brazil
author Gomes, Maria de Lourdes C.
author_facet Gomes, Maria de Lourdes C.
Castro, Ceyla Maria O. de
Oliveira, Maria José C.
Silva, Edson Elias da
author_role author
author2 Castro, Ceyla Maria O. de
Oliveira, Maria José C.
Silva, Edson Elias da
author2_role author
author
author
dc.contributor.author.fl_str_mv Gomes, Maria de Lourdes C.
Castro, Ceyla Maria O. de
Oliveira, Maria José C.
Silva, Edson Elias da
dc.subject.other.pt_BR.fl_str_mv Enterovirus 71
Anticorpos neutralizantes para EV 71
Estudo de soroepidemiologia
Belém
Brasil
topic Enterovirus 71
Anticorpos neutralizantes para EV 71
Estudo de soroepidemiologia
Belém
Brasil
Enterovirus 71
Neutralizing antibodies to EV 71
Seroepidemiology study
Belém
Brazil
dc.subject.en.en.fl_str_mv Enterovirus 71
Neutralizing antibodies to EV 71
Seroepidemiology study
Belém
Brazil
description Fundação Nacional de Saúde. Instituto Evandro Chagas. Seção de Virologia. Belém, PA, Brasil.
publishDate 2002
dc.date.issued.fl_str_mv 2002
dc.date.accessioned.fl_str_mv 2019-11-21T14:03:22Z
dc.date.available.fl_str_mv 2019-11-21T14:03:22Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv GOMES, Maria de Lourdes C. et al. Neutralizing antibodies to Enterovirus 71 in Belém, Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 97, n. 1, p. 47-49, Jan. 2002.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/37226
dc.identifier.issn.pt_BR.fl_str_mv 0074-0206
dc.identifier.doi.pt_BR.fl_str_mv 10.1590/S0074-02762002000100006
dc.identifier.eissn.pt_BR.fl_str_mv 1678-8060
identifier_str_mv GOMES, Maria de Lourdes C. et al. Neutralizing antibodies to Enterovirus 71 in Belém, Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 97, n. 1, p. 47-49, Jan. 2002.
0074-0206
10.1590/S0074-02762002000100006
1678-8060
url https://www.arca.fiocruz.br/handle/icict/37226
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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instacron_str FIOCRUZ
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