Characterizing subpopulations of neoplastic cells in serous effusions. The role of immunocytochemistry

Detalhes bibliográficos
Autor(a) principal: Queiroz, Conceição
Data de Publicação: 2001
Outros Autores: Barral Netto, Manoel, Bacchi, Carlos Eduardo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/29353
Resumo: Barral Netto, Manoel. “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”.
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spelling Queiroz, ConceiçãoBarral Netto, ManoelBacchi, Carlos Eduardo2018-10-04T16:52:33Z2018-10-04T16:52:33Z2001QUEIROZ, C.; BARRAL NETTO, M.; BACCHI, C. E. Characterizing subpopulations of neoplastic cells in serous effusions. The role of immunocytochemistry. Acta Cytologica, v. 45, n.1, p. 18-22, 2001.0001-5547https://www.arca.fiocruz.br/handle/icict/2935310.1159/000327182Barral Netto, Manoel. “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”.Federal University of Bahia. Department of Gynecology, Obstetrics and Human Reproduction. Salvador, BA, BrazilFederal University of Bahia. Department of Anatomic Pathology and Immunology. Salvador, BA, BrazilUniversidade Estadual Paulista. Department of Pathology. São Paulo, SP, BrazilTo analyze the role of immunochemistry in serous effusions. STUDY DESIGN: We analyzed cell blocks of 18 pleural and 18 peritoneal effusions diagnosed as malignant (18), benign (14) and suspicious (4). They were immunostained by the avidin-biotin complex method with a panel of four monoclonal antibodies— CEA, Ber-EP4, LeuM1 (CD15) and p53—and, for lectins (Ulex europaeus) UEA-l, ConA and ConBr. RESULTS: Seventeen of the 18 cases of adenocarcinoma were positive for CEA (95%), 12 (66.6%) for Ber-EP4, 11 (61%) for CD15 and 11 (61%) for p53. Twelve of the 18 (66.6%) were positive for UEA-1, CEA, Ber-EP4 and CD15. UEA-1 did not react with mesothelial cells. p53 Gave a positive reaction in only one case, reactive mesothelial cells. ConA and ConBr reacted indiscriminately with benign and malignant cells; thus, it was not useful in distinguishing between these cells. CONCLUSION: In this context no antibody used alone is reliable for corroborating a diagnosis, but the selective use of a small panel of three markers (CEA, Ber-EP4 and LeuM1) can be very useful in solving diagnostic difficulties in the cytodiagnosis of serous effusions.engKarger PublishersCélulasNeoplasiasImunocitoquímicaEfusões serosasCellsNeoplasmsImmunocytochemistrySerous effusionsCharacterizing subpopulations of neoplastic cells in serous effusions. 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dc.title.pt_BR.fl_str_mv Characterizing subpopulations of neoplastic cells in serous effusions. The role of immunocytochemistry
title Characterizing subpopulations of neoplastic cells in serous effusions. The role of immunocytochemistry
spellingShingle Characterizing subpopulations of neoplastic cells in serous effusions. The role of immunocytochemistry
Queiroz, Conceição
Células
Neoplasias
Imunocitoquímica
Efusões serosas
Cells
Neoplasms
Immunocytochemistry
Serous effusions
title_short Characterizing subpopulations of neoplastic cells in serous effusions. The role of immunocytochemistry
title_full Characterizing subpopulations of neoplastic cells in serous effusions. The role of immunocytochemistry
title_fullStr Characterizing subpopulations of neoplastic cells in serous effusions. The role of immunocytochemistry
title_full_unstemmed Characterizing subpopulations of neoplastic cells in serous effusions. The role of immunocytochemistry
title_sort Characterizing subpopulations of neoplastic cells in serous effusions. The role of immunocytochemistry
author Queiroz, Conceição
author_facet Queiroz, Conceição
Barral Netto, Manoel
Bacchi, Carlos Eduardo
author_role author
author2 Barral Netto, Manoel
Bacchi, Carlos Eduardo
author2_role author
author
dc.contributor.author.fl_str_mv Queiroz, Conceição
Barral Netto, Manoel
Bacchi, Carlos Eduardo
dc.subject.other.pt_BR.fl_str_mv Células
Neoplasias
Imunocitoquímica
Efusões serosas
topic Células
Neoplasias
Imunocitoquímica
Efusões serosas
Cells
Neoplasms
Immunocytochemistry
Serous effusions
dc.subject.en.pt_BR.fl_str_mv Cells
Neoplasms
Immunocytochemistry
Serous effusions
description Barral Netto, Manoel. “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”.
publishDate 2001
dc.date.issued.fl_str_mv 2001
dc.date.accessioned.fl_str_mv 2018-10-04T16:52:33Z
dc.date.available.fl_str_mv 2018-10-04T16:52:33Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.citation.fl_str_mv QUEIROZ, C.; BARRAL NETTO, M.; BACCHI, C. E. Characterizing subpopulations of neoplastic cells in serous effusions. The role of immunocytochemistry. Acta Cytologica, v. 45, n.1, p. 18-22, 2001.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/29353
dc.identifier.issn.pt_BR.fl_str_mv 0001-5547
dc.identifier.doi.none.fl_str_mv 10.1159/000327182
identifier_str_mv QUEIROZ, C.; BARRAL NETTO, M.; BACCHI, C. E. Characterizing subpopulations of neoplastic cells in serous effusions. The role of immunocytochemistry. Acta Cytologica, v. 45, n.1, p. 18-22, 2001.
0001-5547
10.1159/000327182
url https://www.arca.fiocruz.br/handle/icict/29353
dc.language.iso.fl_str_mv eng
language eng
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dc.publisher.none.fl_str_mv Karger Publishers
publisher.none.fl_str_mv Karger Publishers
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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instacron_str FIOCRUZ
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reponame_str Repositório Institucional da FIOCRUZ (ARCA)
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