Association between skin parasitism and a granulomatous inflammatory pattern in canine visceral leishmaniosis

Detalhes bibliográficos
Autor(a) principal: dosSantos, Washington Luis Conrado
Data de Publicação: 2004
Outros Autores: David, John R., Badaró, Roberto José da Silva, Freitas, Luiz Antonio Rodrigues de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/7879
Resumo: Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil / Escola Bahiana de Medicina e Saúde Pública. Salvador, BA, Brasil
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spelling dosSantos, Washington Luis ConradoDavid, John R.Badaró, Roberto José da SilvaFreitas, Luiz Antonio Rodrigues de2014-07-08T13:52:18Z2014-07-08T13:52:18Z2004SANTOS, Washington Luis Conrado dos et al. Association between skin parasitism and a granulomatous inflammatory pattern in canine visceral leishmaniosis. Parasitology, Research, v. 92, n. 2, p. 89-94, 2004.0932-0113https://www.arca.fiocruz.br/handle/icict/787910.1007/s00436-003-1016-1engSpringer VerlagAssociation between skin parasitism and a granulomatous inflammatory pattern in canine visceral leishmaniosisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil / Escola Bahiana de Medicina e Saúde Pública. Salvador, BA, BrasilHarvard School of Public Health. Department of Immunology and Infectious Disease. Boston, Mass., USAUniversidade Federal da Bahia. Faculdade de Medicina da Bahia. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Faculdade de Medicina da Bahia. Salvador, BA, BrasilIn this work we examined 76 stray dogs from an area of endemic visceral leishmaniosis, in order to determine whether the presence of skin inflammation or a specific inflammatory pattern could be taken as indicative of infection with Leishmania chagasi, and whether the parasite burden in the skin could be associated with the intensity or the nature of the inflammatory process. Inflammatory infiltrates were observed in the skin of 51 out of 55 animals with diagnosis of leishmaniosis, and in 17 out of 21 animals without signs of infection. Amastigotes were identified in the skin of 29 out of the 55 animals with diagnosis of leishmaniosis. Granuloma and a monomorphic macrophage inflammatory infiltrate, and not a mixed focal or mixed diffuse inflammation, were significantly associated with skin parasitism, both in terms of frequency ( P=0.015 in the Chi-square test) and intensity ( P=0.005 in the Kruskal-Wallis test). A low parasite burden was associated with a multifocal inflammatory pattern.Doenças do Cão/fisiopatologiaGranuloma/fisiopatologiaInflamação/fisiopatologiaLeishmania/patogenicidadeLeishmaniose Visceral/veterináriaPele/parasitologiaAnimaisDoenças do Cão/parasitologiaCãesGranuloma/parasitologiaInflamação/parasitologiaLeishmaniose Visceral/parasitologiaLeishmaniose Visceral/fisiopatologiainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALSantos WL dos Association between skin....pdfSantos WL dos Association between skin....pdfapplication/pdf408043https://www.arca.fiocruz.br/bitstream/icict/7879/1/Santos%20WL%20dos%20Association%20between%20skin....pdf770e1666270c790aec30ef9497008312MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://www.arca.fiocruz.br/bitstream/icict/7879/2/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD52TEXTSantos WL dos Association between skin....pdf.txtSantos WL dos Association between skin....pdf.txtExtracted texttext/plain27115https://www.arca.fiocruz.br/bitstream/icict/7879/3/Santos%20WL%20dos%20Association%20between%20skin....pdf.txt99782c235033d6142f55d46870e28753MD53icict/78792023-03-15 14:34:16.326oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:34:16Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Association between skin parasitism and a granulomatous inflammatory pattern in canine visceral leishmaniosis
title Association between skin parasitism and a granulomatous inflammatory pattern in canine visceral leishmaniosis
spellingShingle Association between skin parasitism and a granulomatous inflammatory pattern in canine visceral leishmaniosis
dosSantos, Washington Luis Conrado
Doenças do Cão/fisiopatologia
Granuloma/fisiopatologia
Inflamação/fisiopatologia
Leishmania/patogenicidade
Leishmaniose Visceral/veterinária
Pele/parasitologia
Animais
Doenças do Cão/parasitologia
Cães
Granuloma/parasitologia
Inflamação/parasitologia
Leishmaniose Visceral/parasitologia
Leishmaniose Visceral/fisiopatologia
title_short Association between skin parasitism and a granulomatous inflammatory pattern in canine visceral leishmaniosis
title_full Association between skin parasitism and a granulomatous inflammatory pattern in canine visceral leishmaniosis
title_fullStr Association between skin parasitism and a granulomatous inflammatory pattern in canine visceral leishmaniosis
title_full_unstemmed Association between skin parasitism and a granulomatous inflammatory pattern in canine visceral leishmaniosis
title_sort Association between skin parasitism and a granulomatous inflammatory pattern in canine visceral leishmaniosis
author dosSantos, Washington Luis Conrado
author_facet dosSantos, Washington Luis Conrado
David, John R.
Badaró, Roberto José da Silva
Freitas, Luiz Antonio Rodrigues de
author_role author
author2 David, John R.
Badaró, Roberto José da Silva
Freitas, Luiz Antonio Rodrigues de
author2_role author
author
author
dc.contributor.author.fl_str_mv dosSantos, Washington Luis Conrado
David, John R.
Badaró, Roberto José da Silva
Freitas, Luiz Antonio Rodrigues de
dc.subject.decs.pt_BR.fl_str_mv Doenças do Cão/fisiopatologia
Granuloma/fisiopatologia
Inflamação/fisiopatologia
Leishmania/patogenicidade
Leishmaniose Visceral/veterinária
Pele/parasitologia
Animais
Doenças do Cão/parasitologia
Cães
Granuloma/parasitologia
Inflamação/parasitologia
Leishmaniose Visceral/parasitologia
Leishmaniose Visceral/fisiopatologia
topic Doenças do Cão/fisiopatologia
Granuloma/fisiopatologia
Inflamação/fisiopatologia
Leishmania/patogenicidade
Leishmaniose Visceral/veterinária
Pele/parasitologia
Animais
Doenças do Cão/parasitologia
Cães
Granuloma/parasitologia
Inflamação/parasitologia
Leishmaniose Visceral/parasitologia
Leishmaniose Visceral/fisiopatologia
description Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil / Escola Bahiana de Medicina e Saúde Pública. Salvador, BA, Brasil
publishDate 2004
dc.date.issued.fl_str_mv 2004
dc.date.accessioned.fl_str_mv 2014-07-08T13:52:18Z
dc.date.available.fl_str_mv 2014-07-08T13:52:18Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SANTOS, Washington Luis Conrado dos et al. Association between skin parasitism and a granulomatous inflammatory pattern in canine visceral leishmaniosis. Parasitology, Research, v. 92, n. 2, p. 89-94, 2004.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/7879
dc.identifier.issn.none.fl_str_mv 0932-0113
dc.identifier.doi.none.fl_str_mv 10.1007/s00436-003-1016-1
identifier_str_mv SANTOS, Washington Luis Conrado dos et al. Association between skin parasitism and a granulomatous inflammatory pattern in canine visceral leishmaniosis. Parasitology, Research, v. 92, n. 2, p. 89-94, 2004.
0932-0113
10.1007/s00436-003-1016-1
url https://www.arca.fiocruz.br/handle/icict/7879
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Springer Verlag
publisher.none.fl_str_mv Springer Verlag
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
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instacron_str FIOCRUZ
institution FIOCRUZ
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collection Repositório Institucional da FIOCRUZ (ARCA)
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