Neurological manifestations of coinfection with HIV and HTLV-1
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/36375 |
Resumo: | 2020-10-11 |
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Silva, Marcus T. T.Neves, Elizabeth S.Grinsztejn, BeatrizEspíndola, Otávio de MeloSchor, DorisAraújo, Abelardo2019-10-11T11:59:15Z2019-10-11T11:59:15Z2012SILVA, Marcus T. T. et al. Neurological manifestations of coinfection with HIV and human T-lymphotropic virus type 1. AIDS, v. 26, n. 4, p. 521-523, 2012.0269-9370https://www.arca.fiocruz.br/handle/icict/3637510.1097/QAD.0b013e32835049be1473-5571engLippincott, Williams & WilkinsNeurological manifestations of coinfection with HIV and HTLV-1info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2020-10-11Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa Clínica em Neuroinfecção. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa Clínica em Neuroinfecção. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa em Patogenia Viral. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa em Patogenia Viral. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa Clínica em Neuroinfecção. Rio de Janeiro, RJ, Brasil.HIV-individuals are at risk for human T-lymphotropic virus (HTLV) coinfection and neurological diseases. Little is known about the impact of HAART among coinfected patients. In this study, 47 out of 428 HIV individuals were coinfected with HTLV (10.9%). Coinfection was an independent variable associated with neurological outcome (odds ratio 8.73). Coinfection was associated with myelopathy [chi square (X2 ) U 93, P< 0.001], peripheral neuropathy (X2 U 6.5, P U 0.01), and hepatitis C virus infection (X2 U 36.5, P< 0.001). HAART did not appear to protect against neurological diseases and had no impact on HTLV proviral load.HIVHTLV-1Neurological manifestationsCoinfectioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/36375/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALve_Silva_Marcus_etal_INI_2012.pdfve_Silva_Marcus_etal_INI_2012.pdfapplication/pdf197676https://www.arca.fiocruz.br/bitstream/icict/36375/2/ve_Silva_Marcus_etal_INI_2012.pdfa13cc021eb7310755424f8835866c8ceMD52TEXTve_Silva_Marcus_etal_INI_2012.pdf.txtve_Silva_Marcus_etal_INI_2012.pdf.txtExtracted texttext/plain29238https://www.arca.fiocruz.br/bitstream/icict/36375/3/ve_Silva_Marcus_etal_INI_2012.pdf.txtc0342e00522aa5d5fde09bb6a0e82c38MD53icict/363752021-03-24 16:32:37.397oai:www.arca.fiocruz.br:icict/36375Tk9URTogUExBQ0UgWU9VUiBPV04gTElDRU5TRSBIRVJFClRoaXMgc2FtcGxlIGxpY2Vuc2UgaXMgcHJvdmlkZWQgZm9yIGluZm9ybWF0aW9uYWwgcHVycG9zZXMgb25seS4KCk5PTi1FWENMVVNJVkUgRElTVFJJQlVUSU9OIExJQ0VOU0UKCkJ5IHNpZ25pbmcgYW5kIHN1Ym1pdHRpbmcgdGhpcyBsaWNlbnNlLCB5b3UgKHRoZSBhdXRob3Iocykgb3IgY29weXJpZ2h0Cm93bmVyKSBncmFudHMgdG8gRFNwYWNlIFVuaXZlcnNpdHkgKERTVSkgdGhlIG5vbi1leGNsdXNpdmUgcmlnaHQgdG8gcmVwcm9kdWNlLAp0cmFuc2xhdGUgKGFzIGRlZmluZWQgYmVsb3cpLCBhbmQvb3IgZGlzdHJpYnV0ZSB5b3VyIHN1Ym1pc3Npb24gKGluY2x1ZGluZwp0aGUgYWJzdHJhY3QpIHdvcmxkd2lkZSBpbiBwcmludCBhbmQgZWxlY3Ryb25pYyBmb3JtYXQgYW5kIGluIGFueSBtZWRpdW0sCmluY2x1ZGluZyBidXQgbm90IGxpbWl0ZWQgdG8gYXVkaW8gb3IgdmlkZW8uCgpZb3UgYWdyZWUgdGhhdCBEU1UgbWF5LCB3aXRob3V0IGNoYW5naW5nIHRoZSBjb250ZW50LCB0cmFuc2xhdGUgdGhlCnN1Ym1pc3Npb24gdG8gYW55IG1lZGl1bSBvciBmb3JtYXQgZm9yIHRoZSBwdXJwb3NlIG9mIHByZXNlcnZhdGlvbi4KCllvdSBhbHNvIGFncmVlIHRoYXQgRFNVIG1heSBrZWVwIG1vcmUgdGhhbiBvbmUgY29weSBvZiB0aGlzIHN1Ym1pc3Npb24gZm9yCnB1cnBvc2VzIG9mIHNlY3VyaXR5LCBiYWNrLXVwIGFuZCBwcmVzZXJ2YXRpb24uCgpZb3UgcmVwcmVzZW50IHRoYXQgdGhlIHN1Ym1pc3Npb24gaXMgeW91ciBvcmlnaW5hbCB3b3JrLCBhbmQgdGhhdCB5b3UgaGF2ZQp0aGUgcmlnaHQgdG8gZ3JhbnQgdGhlIHJpZ2h0cyBjb250YWluZWQgaW4gdGhpcyBsaWNlbnNlLiBZb3UgYWxzbyByZXByZXNlbnQKdGhhdCB5b3VyIHN1Ym1pc3Npb24gZG9lcyBub3QsIHRvIHRoZSBiZXN0IG9mIHlvdXIga25vd2xlZGdlLCBpbmZyaW5nZSB1cG9uCmFueW9uZSdzIGNvcHlyaWdodC4KCklmIHRoZSBzdWJtaXNzaW9uIGNvbnRhaW5zIG1hdGVyaWFsIGZvciB3aGljaCB5b3UgZG8gbm90IGhvbGQgY29weXJpZ2h0LAp5b3UgcmVwcmVzZW50IHRoYXQgeW91IGhhdmUgb2J0YWluZWQgdGhlIHVucmVzdHJpY3RlZCBwZXJtaXNzaW9uIG9mIHRoZQpjb3B5cmlnaHQgb3duZXIgdG8gZ3JhbnQgRFNVIHRoZSByaWdodHMgcmVxdWlyZWQgYnkgdGhpcyBsaWNlbnNlLCBhbmQgdGhhdApzdWNoIHRoaXJkLXBhcnR5IG93bmVkIG1hdGVyaWFsIGlzIGNsZWFybHkgaWRlbnRpZmllZCBhbmQgYWNrbm93bGVkZ2VkCndpdGhpbiB0aGUgdGV4dCBvciBjb250ZW50IG9mIHRoZSBzdWJtaXNzaW9uLgoKSUYgVEhFIFNVQk1JU1NJT04gSVMgQkFTRUQgVVBPTiBXT1JLIFRIQVQgSEFTIEJFRU4gU1BPTlNPUkVEIE9SIFNVUFBPUlRFRApCWSBBTiBBR0VOQ1kgT1IgT1JHQU5JWkFUSU9OIE9USEVSIFRIQU4gRFNVLCBZT1UgUkVQUkVTRU5UIFRIQVQgWU9VIEhBVkUKRlVMRklMTEVEIEFOWSBSSUdIVCBPRiBSRVZJRVcgT1IgT1RIRVIgT0JMSUdBVElPTlMgUkVRVUlSRUQgQlkgU1VDSApDT05UUkFDVCBPUiBBR1JFRU1FTlQuCgpEU1Ugd2lsbCBjbGVhcmx5IGlkZW50aWZ5IHlvdXIgbmFtZShzKSBhcyB0aGUgYXV0aG9yKHMpIG9yIG93bmVyKHMpIG9mIHRoZQpzdWJtaXNzaW9uLCBhbmQgd2lsbCBub3QgbWFrZSBhbnkgYWx0ZXJhdGlvbiwgb3RoZXIgdGhhbiBhcyBhbGxvd2VkIGJ5IHRoaXMKbGljZW5zZSwgdG8geW91ciBzdWJtaXNzaW9uLgo=Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352021-03-24T19:32:37Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.pt_BR.fl_str_mv |
Neurological manifestations of coinfection with HIV and HTLV-1 |
title |
Neurological manifestations of coinfection with HIV and HTLV-1 |
spellingShingle |
Neurological manifestations of coinfection with HIV and HTLV-1 Silva, Marcus T. T. HIV HTLV-1 Neurological manifestations Coinfection |
title_short |
Neurological manifestations of coinfection with HIV and HTLV-1 |
title_full |
Neurological manifestations of coinfection with HIV and HTLV-1 |
title_fullStr |
Neurological manifestations of coinfection with HIV and HTLV-1 |
title_full_unstemmed |
Neurological manifestations of coinfection with HIV and HTLV-1 |
title_sort |
Neurological manifestations of coinfection with HIV and HTLV-1 |
author |
Silva, Marcus T. T. |
author_facet |
Silva, Marcus T. T. Neves, Elizabeth S. Grinsztejn, Beatriz Espíndola, Otávio de Melo Schor, Doris Araújo, Abelardo |
author_role |
author |
author2 |
Neves, Elizabeth S. Grinsztejn, Beatriz Espíndola, Otávio de Melo Schor, Doris Araújo, Abelardo |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Silva, Marcus T. T. Neves, Elizabeth S. Grinsztejn, Beatriz Espíndola, Otávio de Melo Schor, Doris Araújo, Abelardo |
dc.subject.en.pt_BR.fl_str_mv |
HIV HTLV-1 Neurological manifestations Coinfection |
topic |
HIV HTLV-1 Neurological manifestations Coinfection |
description |
2020-10-11 |
publishDate |
2012 |
dc.date.issued.fl_str_mv |
2012 |
dc.date.accessioned.fl_str_mv |
2019-10-11T11:59:15Z |
dc.date.available.fl_str_mv |
2019-10-11T11:59:15Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
SILVA, Marcus T. T. et al. Neurological manifestations of coinfection with HIV and human T-lymphotropic virus type 1. AIDS, v. 26, n. 4, p. 521-523, 2012. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/36375 |
dc.identifier.issn.pt_BR.fl_str_mv |
0269-9370 |
dc.identifier.doi.none.fl_str_mv |
10.1097/QAD.0b013e32835049be |
dc.identifier.eissn.none.fl_str_mv |
1473-5571 |
identifier_str_mv |
SILVA, Marcus T. T. et al. Neurological manifestations of coinfection with HIV and human T-lymphotropic virus type 1. AIDS, v. 26, n. 4, p. 521-523, 2012. 0269-9370 10.1097/QAD.0b013e32835049be 1473-5571 |
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https://www.arca.fiocruz.br/handle/icict/36375 |
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eng |
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eng |
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info:eu-repo/semantics/openAccess |
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openAccess |
dc.publisher.none.fl_str_mv |
Lippincott, Williams & Wilkins |
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Lippincott, Williams & Wilkins |
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