Efeito da quimioterapia sobre os ovos do Schistosoma mansoni.

Detalhes bibliográficos
Autor(a) principal: Reis, Mitermayer Galvão dos
Data de Publicação: 1987
Outros Autores: Andrade, Zilton de Araújo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/5736
Resumo: Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
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spelling Reis, Mitermayer Galvão dosAndrade, Zilton de Araújo2012-10-26T17:48:21Z2012-10-26T17:48:21Z1987REIS, M.G. dos; ANDRADE, Z.A. Efeito da quimioterapia sobre os ovos do Schistosoma mansoni. Memórias do Instituto Oswaldo Cruz, v. 82, n. 2, p. 161-5, apr.-jun. 1987.0074-0276https://www.arca.fiocruz.br/handle/icict/5736engEfeito da quimioterapia sobre os ovos do Schistosoma mansoni.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilPraziquantel administered to mice with Schistosoma mansoni infection (50 cercarias/8 weeks) was observed to cause death of adult worms and disintegration of the eggs trapped within granulomas, sometimes with calcification, after the 4th day of treatment. Combined administration of oxamniquine/hycanthone to animals similarly infected, although quite effective in killing adult worms, did not interfere with the eggs in the tissue. The miracidium eclosion test was positive up to the 15th day after the curative treatment of these animals. Since praziquantel treatment causes a rapid destruction of eggs, possible serological and pathogenic effects are expected that may enable a faster reabsorption of granulomas by the host tissues than that produced by other equally effective drugs.ChemotherapyMiracidiumSchistosoma MansoniPraziquantelOxamniquine/hycanthoneÓvulo/efeitos de drogasPraziquantel/farmacologiaSchistosoma mansoni/efeitos de drogasEsquistossomose mansoni/quimioterapiaAnimaisQuimioterapia CombinadaFemininoHicantone/farmacologiaMasculinoCamundongosOxamniquine/farmacologiainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALdos Reis MG Effect of chemotherapy....pdfdos Reis MG Effect of chemotherapy....pdfapplication/pdf224737https://www.arca.fiocruz.br/bitstream/icict/5736/1/dos%20Reis%20MG%20Effect%20of%20chemotherapy....pdfd7a550447fe1f7bce8f88ec272ea8adaMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-82008https://www.arca.fiocruz.br/bitstream/icict/5736/2/license.txt06db3f0df647fd9ddff657403bbe0ee2MD52TEXTdos Reis MG Effect of chemotherapy....pdf.txtdos Reis MG Effect of chemotherapy....pdf.txtExtracted texttext/plain5https://www.arca.fiocruz.br/bitstream/icict/5736/5/dos%20Reis%20MG%20Effect%20of%20chemotherapy....pdf.txtcc9067c2ee470dc248b14b194209a34eMD55THUMBNAILdos Reis MG Effect of chemotherapy....pdf.jpgdos Reis MG Effect of chemotherapy....pdf.jpgGenerated Thumbnailimage/jpeg2397https://www.arca.fiocruz.br/bitstream/icict/5736/4/dos%20Reis%20MG%20Effect%20of%20chemotherapy....pdf.jpged5f1b420d57ef9ade7c79978c0e941bMD54icict/57362023-03-15 14:32:55.373oai:www.arca.fiocruz.br:icict/5736TElDRU7Dh0EgREUgRElTVFJJQlVJw4fDg08gTsODTy1FWENMVVNJVkEKCkFvIGFzc2luYXIgZSBlbnRyZWdhciBlc3RhIGxpY2Vuw6dhLCBvL2EgU3IuL1NyYS4gKGF1dG9yIG91IGRldGVudG9yIGRvcyBkaXJlaXRvcyBkbyBhdXRvcik6CgpBbyBjb25jb3JkYXIgZSBhY2VpdGFyIGVzdGEgbGljZW7Dp2Egdm9jw6ogKGF1dG9yIG91IGRldGVudG9yIGRvcyBkaXJlaXRvcyBhdXRvcmFpcyk6CgphKSBEZWNsYXJhIHF1ZSBjb25oZWNlIGEgcG9sw610aWNhIGRlIGNvcHlyaWdodCBkYSBlZGl0b3JhIGRvIHNldSBkb2N1bWVudG8uCgpiKSBEZWNsYXJhIHF1ZSBjb25oZWNlIGUgYWNlaXRhIGFzIERpcmV0cml6ZXMgcGFyYSBvIFJlcG9zaXTDs3JpbyBJbnN0aXR1Y2lvbmFsIGRhIEZ1bmRhw6fDo28gT3N3YWxkbyBDcnV6IChGSU9DUlVaKS4KCmMpIENvbmNlZGUgw6AgRklPQ1JVWiBvIGRpcmVpdG8gbsOjby1leGNsdXNpdm8gZGUgYXJxdWl2YXIsIHJlcHJvZHV6aXIsIGNvbnZlcnRlciAoY29tbyBkZWZpbmlkbyBhIHNlZ3VpciksIGNvbXVuaWNhcgogCmUvb3UgZGlzdHJpYnVpciBubyBSZXBvc2l0w7NyaW8gZGEgRklPQ1JVWiwgbyBkb2N1bWVudG8gZW50cmVndWUgKGluY2x1aW5kbyBvIHJlc3Vtby9hYnN0cmFjdCkgZW0gZm9ybWF0byBkaWdpdGFsIG91IAoKcG9yIHF1YWxxdWVyIG91dHJvIG1laW8uCgpkKSBEZWNsYXJhIHF1ZSBhdXRvcml6YSBhIEZJT0NSVVogYSBhcnF1aXZhciBtYWlzIGRlIHVtYSBjw7NwaWEgZGVzdGUgZG9jdW1lbnRvIGUgY29udmVydMOqLWxvLCBzZW0gYWx0ZXJhciBvIHNldSBjb250ZcO6ZG8sIAoKcGFyYSBxdWFscXVlciBmb3JtYXRvIGRlIGFycXVpdm8sIG1laW8gb3Ugc3Vwb3J0ZSwgcGFyYSBlZmVpdG9zIGRlIHNlZ3VyYW7Dp2EsIHByZXNlcnZhw6fDo28gKGJhY2t1cCkgZSBhY2Vzc28uCgplKSBEZWNsYXJhIHF1ZSBvIGRvY3VtZW50byBzdWJtZXRpZG8gw6kgbyBzZXUgdHJhYmFsaG8gb3JpZ2luYWwsIGUgcXVlIGRldMOpbSBvIGRpcmVpdG8gZGUgY29uY2VkZXIgYSB0ZXJjZWlyb3Mgb3MgZGlyZWl0b3MgCgpjb250aWRvcyBuZXN0YSBsaWNlbsOnYS4gRGVjbGFyYSB0YW1iw6ltIHF1ZSBhIGVudHJlZ2EgZG8gZG9jdW1lbnRvIG7Do28gaW5mcmluZ2Ugb3MgZGlyZWl0b3MgZGUgcXVhbHF1ZXIgb3V0cmEgcGVzc29hIG91IGVudGlkYWRlLgoKZikgRGVjbGFyYSBxdWUsIG5vIGNhc28gZG8gZG9jdW1lbnRvIHN1Ym1ldGlkbyBjb250ZXIgbWF0ZXJpYWwgZG8gcXVhbCBuw6NvIGRldMOpbSBvcyBkaXJlaXRvcyBkZSBhdXRvciwgb2J0ZXZlIGEgYXV0b3JpemHDp8OjbyAKCmlycmVzdHJpdGEgZG8gcmVzcGVjdGl2byBkZXRlbnRvciBkZXNzZXMgZGlyZWl0b3MsIHBhcmEgY2VkZXIgYSBGSU9DUlVaIG9zIGRpcmVpdG9zIHJlcXVlcmlkb3MgcG9yIGVzdGEgTGljZW7Dp2EgZSBhdXRvcml6YXIgYSAKCnV0aWxpesOhLWxvcyBsZWdhbG1lbnRlLiBEZWNsYXJhIHRhbWLDqW0gcXVlIGVzc2UgbWF0ZXJpYWwgY3Vqb3MgZGlyZWl0b3Mgc8OjbyBkZSB0ZXJjZWlyb3MgZXN0w6EgY2xhcmFtZW50ZSBpZGVudGlmaWNhZG8gZSByZWNvbmhlY2lkbyAKCm5vIHRleHRvIG91IGNvbnRlw7pkbyBkbyBkb2N1bWVudG8gZW50cmVndWUuCgpnKSBTRSBPIERPQ1VNRU5UTyBFTlRSRUdVRSDDiSBCQVNFQURPIEVNIFRSQUJBTEhPIEZJTkFOQ0lBRE8gT1UgQVBPSUFETyBQT1IgT1VUUkEgSU5TVElUVUnDh8ODTyBRVUUgTsODTyBBIEZJT0NSVVosIERFQ0xBUkEgUVVFIENVTVBSSVUgCgpRVUFJU1FVRVIgT0JSSUdBw4fDlUVTIEVYSUdJREFTIFBFTE8gUkVTUEVDVElWTyBDT05UUkFUTyBPVSBBQ09SRE8uIEEgRklPQ1JVWiBpZGVudGlmaWNhcsOhIGNsYXJhbWVudGUgbyhzKSBub21lKHMpIGRvKHMpIGF1dG9yKGVzKSBkb3MgCgpkaXJlaXRvcyBkbyBkb2N1bWVudG8gZW50cmVndWUgZSBuw6NvIGZhcsOhIHF1YWxxdWVyIGFsdGVyYcOnw6NvLCBwYXJhIGFsw6ltIGRvIHByZXZpc3RvIG5hIGFsw61uZWEgYykuCg==Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:32:55Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Efeito da quimioterapia sobre os ovos do Schistosoma mansoni.
title Efeito da quimioterapia sobre os ovos do Schistosoma mansoni.
spellingShingle Efeito da quimioterapia sobre os ovos do Schistosoma mansoni.
Reis, Mitermayer Galvão dos
Chemotherapy
Miracidium
Schistosoma Mansoni
Praziquantel
Oxamniquine/hycanthone
Óvulo/efeitos de drogas
Praziquantel/farmacologia
Schistosoma mansoni/efeitos de drogas
Esquistossomose mansoni/quimioterapia
Animais
Quimioterapia Combinada
Feminino
Hicantone/farmacologia
Masculino
Camundongos
Oxamniquine/farmacologia
title_short Efeito da quimioterapia sobre os ovos do Schistosoma mansoni.
title_full Efeito da quimioterapia sobre os ovos do Schistosoma mansoni.
title_fullStr Efeito da quimioterapia sobre os ovos do Schistosoma mansoni.
title_full_unstemmed Efeito da quimioterapia sobre os ovos do Schistosoma mansoni.
title_sort Efeito da quimioterapia sobre os ovos do Schistosoma mansoni.
author Reis, Mitermayer Galvão dos
author_facet Reis, Mitermayer Galvão dos
Andrade, Zilton de Araújo
author_role author
author2 Andrade, Zilton de Araújo
author2_role author
dc.contributor.author.fl_str_mv Reis, Mitermayer Galvão dos
Andrade, Zilton de Araújo
dc.subject.en.pt_BR.fl_str_mv Chemotherapy
Miracidium
Schistosoma Mansoni
Praziquantel
Oxamniquine/hycanthone
topic Chemotherapy
Miracidium
Schistosoma Mansoni
Praziquantel
Oxamniquine/hycanthone
Óvulo/efeitos de drogas
Praziquantel/farmacologia
Schistosoma mansoni/efeitos de drogas
Esquistossomose mansoni/quimioterapia
Animais
Quimioterapia Combinada
Feminino
Hicantone/farmacologia
Masculino
Camundongos
Oxamniquine/farmacologia
dc.subject.decs.pt_BR.fl_str_mv Óvulo/efeitos de drogas
Praziquantel/farmacologia
Schistosoma mansoni/efeitos de drogas
Esquistossomose mansoni/quimioterapia
Animais
Quimioterapia Combinada
Feminino
Hicantone/farmacologia
Masculino
Camundongos
Oxamniquine/farmacologia
description Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
publishDate 1987
dc.date.issued.fl_str_mv 1987
dc.date.accessioned.fl_str_mv 2012-10-26T17:48:21Z
dc.date.available.fl_str_mv 2012-10-26T17:48:21Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv REIS, M.G. dos; ANDRADE, Z.A. Efeito da quimioterapia sobre os ovos do Schistosoma mansoni. Memórias do Instituto Oswaldo Cruz, v. 82, n. 2, p. 161-5, apr.-jun. 1987.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/5736
dc.identifier.issn.none.fl_str_mv 0074-0276
identifier_str_mv REIS, M.G. dos; ANDRADE, Z.A. Efeito da quimioterapia sobre os ovos do Schistosoma mansoni. Memórias do Instituto Oswaldo Cruz, v. 82, n. 2, p. 161-5, apr.-jun. 1987.
0074-0276
url https://www.arca.fiocruz.br/handle/icict/5736
dc.language.iso.fl_str_mv eng
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