E-cadherin regulators are differentially expressed in the epithelium and stroma of keratocystic odontogenic tumors
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/25532 |
Resumo: | Gurgel, Clarissa Araújo. “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”. |
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Porto, Lia Pontes ArrudaSantos, Jean Nunes dosRamalho, Luciana Maria PedreiraFigueiredo, Andreia LealCarneiro Júnior, BráulioGurgel, Clarissa AraújoPaiva, Katiúcia Batista SilvaXavier, Flávia Caló Aquino2018-03-27T17:25:16Z2018-03-27T17:25:16Z2016PORTO, L. P. A. et al. E-cadherin regulators are differentially expressed in the epithelium and stroma of keratocystic odontogenic tumors. Journal of Oral Pathology & Medicine, v. 45, p. 302–311, 2016.0904-2512https://www.arca.fiocruz.br/handle/icict/2553210.1111/jop.12382Gurgel, Clarissa Araújo. “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”.Federal University of Bahia. School of Dentistry. Pos-graduate of Dentistry and Health. Salvador, BA, BrazilFederal University of Bahia. School of Dentistry. Department of Propaedeutics and Integrated Clinical Practicum. Surgical Pathology Laboratory. Salvador, BA, BrazilFederal University of Bahia. School of Dentistry. Department of Propaedeutics and Integrated Clinical Practicum. Salvador, BA, BrazilFederal University of Bahia. School of Dentistry. Department of Social and Pediatric Dentistry. Salvador, BA, BrazilFederal University of Bahia. School of Dentistry. Pos-graduate of Dentistry and Health. Salvador, BA, BrazilFederal University of Bahia. School of Dentistry. Department of Propaedeutics and Integrated Clinical Practicum. Salvador, BA, BrazilUniversity of São Paulo. Institute of Biomedical Sciences. Department of Anatomy, Extracellular Matrix Biology and Cellular Interaction Laboratory. São Paulo, SP, BrazilFederal University of Bahia. School of Dentistry. Department of Propaedeutics and Integrated Clinical Practicum. Surgical Pathology Laboratory. Salvador, BA, BrazilThe epithelial-mesenchymal transition (EMT) is the process where cells lose their epithelial features and acquire properties of typical mesenchymal cells. The dissociation of tumor cells due to changes in cell-cell adhesion is one of the key principles of tumor invasion and EMT. Thus, the knowledge of the molecular features of EMT in keratocyst odontogenic tumor (KOT) can provide useful markers to aid in the diagnosis and prognosis and perhaps contribute to an alternative therapeutic approach as it shows an aggressive clinical behavior and high recurrence rates. This study aimed to evaluate the EMT in KOT by the immunoexpression of E-cadherin, N-cadherin, Snail, and Slug and comparing to radicular cysts and dental follicles.engWileyAdesão celularE-caderinaTransição epitelial-mesenquimalImuno-histoquímicaTumores odontogênicosCell adhesionE-cadherinEpithelial–mesenchymal transitionImmunohistochemistryOdontogenic tumorsE-cadherin regulators are differentially expressed in the epithelium and stroma of keratocystic odontogenic tumorsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/25532/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALPorto LP E-cadherin regulators are differentially ....pdfPorto LP E-cadherin regulators are differentially 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14:34:10.203oai:www.arca.fiocruz.br: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ório 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dc.title.pt_BR.fl_str_mv |
E-cadherin regulators are differentially expressed in the epithelium and stroma of keratocystic odontogenic tumors |
title |
E-cadherin regulators are differentially expressed in the epithelium and stroma of keratocystic odontogenic tumors |
spellingShingle |
E-cadherin regulators are differentially expressed in the epithelium and stroma of keratocystic odontogenic tumors Porto, Lia Pontes Arruda Adesão celular E-caderina Transição epitelial-mesenquimal Imuno-histoquímica Tumores odontogênicos Cell adhesion E-cadherin Epithelial–mesenchymal transition Immunohistochemistry Odontogenic tumors |
title_short |
E-cadherin regulators are differentially expressed in the epithelium and stroma of keratocystic odontogenic tumors |
title_full |
E-cadherin regulators are differentially expressed in the epithelium and stroma of keratocystic odontogenic tumors |
title_fullStr |
E-cadherin regulators are differentially expressed in the epithelium and stroma of keratocystic odontogenic tumors |
title_full_unstemmed |
E-cadherin regulators are differentially expressed in the epithelium and stroma of keratocystic odontogenic tumors |
title_sort |
E-cadherin regulators are differentially expressed in the epithelium and stroma of keratocystic odontogenic tumors |
author |
Porto, Lia Pontes Arruda |
author_facet |
Porto, Lia Pontes Arruda Santos, Jean Nunes dos Ramalho, Luciana Maria Pedreira Figueiredo, Andreia Leal Carneiro Júnior, Bráulio Gurgel, Clarissa Araújo Paiva, Katiúcia Batista Silva Xavier, Flávia Caló Aquino |
author_role |
author |
author2 |
Santos, Jean Nunes dos Ramalho, Luciana Maria Pedreira Figueiredo, Andreia Leal Carneiro Júnior, Bráulio Gurgel, Clarissa Araújo Paiva, Katiúcia Batista Silva Xavier, Flávia Caló Aquino |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Porto, Lia Pontes Arruda Santos, Jean Nunes dos Ramalho, Luciana Maria Pedreira Figueiredo, Andreia Leal Carneiro Júnior, Bráulio Gurgel, Clarissa Araújo Paiva, Katiúcia Batista Silva Xavier, Flávia Caló Aquino |
dc.subject.other.pt_BR.fl_str_mv |
Adesão celular E-caderina Transição epitelial-mesenquimal Imuno-histoquímica Tumores odontogênicos |
topic |
Adesão celular E-caderina Transição epitelial-mesenquimal Imuno-histoquímica Tumores odontogênicos Cell adhesion E-cadherin Epithelial–mesenchymal transition Immunohistochemistry Odontogenic tumors |
dc.subject.en.pt_BR.fl_str_mv |
Cell adhesion E-cadherin Epithelial–mesenchymal transition Immunohistochemistry Odontogenic tumors |
description |
Gurgel, Clarissa Araújo. “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”. |
publishDate |
2016 |
dc.date.issued.fl_str_mv |
2016 |
dc.date.accessioned.fl_str_mv |
2018-03-27T17:25:16Z |
dc.date.available.fl_str_mv |
2018-03-27T17:25:16Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
PORTO, L. P. A. et al. E-cadherin regulators are differentially expressed in the epithelium and stroma of keratocystic odontogenic tumors. Journal of Oral Pathology & Medicine, v. 45, p. 302–311, 2016. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/25532 |
dc.identifier.issn.pt_BR.fl_str_mv |
0904-2512 |
dc.identifier.doi.none.fl_str_mv |
10.1111/jop.12382 |
identifier_str_mv |
PORTO, L. P. A. et al. E-cadherin regulators are differentially expressed in the epithelium and stroma of keratocystic odontogenic tumors. Journal of Oral Pathology & Medicine, v. 45, p. 302–311, 2016. 0904-2512 10.1111/jop.12382 |
url |
https://www.arca.fiocruz.br/handle/icict/25532 |
dc.language.iso.fl_str_mv |
eng |
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eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
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openAccess |
dc.publisher.none.fl_str_mv |
Wiley |
publisher.none.fl_str_mv |
Wiley |
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