The red flags of ulnar neuropathy in leprosy

Detalhes bibliográficos
Autor(a) principal: Jardim, Márcia
Data de Publicação: 2021
Outros Autores: Vital, Robson T., Illarramendi, Ximena, Hacker, Mariana, Junqueira, Beatriz, Pitta, Izabela J. R., Pinheiro, Roberta O., Sarno, Euzenir N.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/51077
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil / Universidade do Estado do Rio de Janeiro. Hospital Pedro Ernesto. Departamento de Neurologia. Rio de Janeiro, RJ, Brasil / Universidade Federal do Estado do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.
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spelling Jardim, MárciaVital, Robson T.Illarramendi, XimenaHacker, MarianaJunqueira, BeatrizPitta, Izabela J. R.Pinheiro, Roberta O.Sarno, Euzenir N.2022-02-08T15:01:14Z2022-02-08T15:01:14Z2021JARDIM, Márcia et al. The red flags of ulnar neuropathy in leprosy. Plos One, v. 16, n. 11, e0259804, p. 1 - 11, Nov. 2021.1932-6203https://www.arca.fiocruz.br/handle/icict/5107710.1371/journal. pone.0259804engPublic Library of ScienceHanseníaseNeuropatia ulnarDiagnósticoUlnar neuropathyLeprosyDiagnosisThe red flags of ulnar neuropathy in leprosyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil / Universidade do Estado do Rio de Janeiro. Hospital Pedro Ernesto. Departamento de Neurologia. Rio de Janeiro, RJ, Brasil / Universidade Federal do Estado do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.Universidade do Estado do Rio de Janeiro. Hospital Pedro Ernesto. Departamento de Neurologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, BrasilFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, BrasilFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil / Universidade do Estado do Rio de Janeiro. Hospital Pedro Ernesto. Departamento de Neurologia. Rio de Janeiro, RJ, Brasil / Universidade Federal do Estado do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, BrasilFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, BrasilThe diagnosis of pure neural leprosy is more challenging because patients share characteristics with other common pathologies, such as ulnar compression, which should be taken into consideration for differential diagnosis. In this study, we identify ulnar nerve conduction characteristics to aid in the differential diagnosis of ulnar neuropathy (UN) in leprosy and that of non-leprosy etiology. In addition, we include putative markers to better understand the inflammatory process that may occur in the nerve. Data were extracted from a database of people affected by leprosy (leprosy group) diagnosed with UN at leprosy diagnosis. A non-leprosy group of patients diagnosed with mechanical neuropathy (compressive, traumatic) was also included. Both groups were submitted to clinical, neurological, neurophysiological and immunological studies. Nerve enlargement and sensory impairment were significantly higher in leprosy patients than in patients with compressive UN. Bilateral impairment was significantly higher in the leprosy group than in the non-leprosy group. Leprosy reactions were associated to focal demyelinating lesions at the elbow and to temporal dispersion (TD). Clinical signs such as sensory impairment, nerve enlargement and bilateral ulnar nerve injury associated with eletrodiagnostic criteria such as demyelinating finds, specifically temporal dispersion, could be tools to help us decided on the best conduct in patients with elbow ulnar neuropathy and specifically decide if we should perform a nerve biopsy for diagnosis of pure neural leprosy.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/51077/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALMarciaJardim_IsabelaPitta_etal_IOC_2021.pdfMarciaJardim_IsabelaPitta_etal_IOC_2021.pdfapplication/pdf679019https://www.arca.fiocruz.br/bitstream/icict/51077/2/MarciaJardim_IsabelaPitta_etal_IOC_2021.pdff292e6b33f9ce5ef7b454b9d96c56cd8MD52icict/510772022-02-08 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dc.title.pt_BR.fl_str_mv The red flags of ulnar neuropathy in leprosy
title The red flags of ulnar neuropathy in leprosy
spellingShingle The red flags of ulnar neuropathy in leprosy
Jardim, Márcia
Hanseníase
Neuropatia ulnar
Diagnóstico
Ulnar neuropathy
Leprosy
Diagnosis
title_short The red flags of ulnar neuropathy in leprosy
title_full The red flags of ulnar neuropathy in leprosy
title_fullStr The red flags of ulnar neuropathy in leprosy
title_full_unstemmed The red flags of ulnar neuropathy in leprosy
title_sort The red flags of ulnar neuropathy in leprosy
author Jardim, Márcia
author_facet Jardim, Márcia
Vital, Robson T.
Illarramendi, Ximena
Hacker, Mariana
Junqueira, Beatriz
Pitta, Izabela J. R.
Pinheiro, Roberta O.
Sarno, Euzenir N.
author_role author
author2 Vital, Robson T.
Illarramendi, Ximena
Hacker, Mariana
Junqueira, Beatriz
Pitta, Izabela J. R.
Pinheiro, Roberta O.
Sarno, Euzenir N.
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Jardim, Márcia
Vital, Robson T.
Illarramendi, Ximena
Hacker, Mariana
Junqueira, Beatriz
Pitta, Izabela J. R.
Pinheiro, Roberta O.
Sarno, Euzenir N.
dc.subject.other.pt_BR.fl_str_mv Hanseníase
Neuropatia ulnar
Diagnóstico
topic Hanseníase
Neuropatia ulnar
Diagnóstico
Ulnar neuropathy
Leprosy
Diagnosis
dc.subject.en.pt_BR.fl_str_mv Ulnar neuropathy
Leprosy
Diagnosis
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil / Universidade do Estado do Rio de Janeiro. Hospital Pedro Ernesto. Departamento de Neurologia. Rio de Janeiro, RJ, Brasil / Universidade Federal do Estado do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.
publishDate 2021
dc.date.issued.fl_str_mv 2021
dc.date.accessioned.fl_str_mv 2022-02-08T15:01:14Z
dc.date.available.fl_str_mv 2022-02-08T15:01:14Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv JARDIM, Márcia et al. The red flags of ulnar neuropathy in leprosy. Plos One, v. 16, n. 11, e0259804, p. 1 - 11, Nov. 2021.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/51077
dc.identifier.issn.pt_BR.fl_str_mv 1932-6203
dc.identifier.doi.none.fl_str_mv 10.1371/journal. pone.0259804
identifier_str_mv JARDIM, Márcia et al. The red flags of ulnar neuropathy in leprosy. Plos One, v. 16, n. 11, e0259804, p. 1 - 11, Nov. 2021.
1932-6203
10.1371/journal. pone.0259804
url https://www.arca.fiocruz.br/handle/icict/51077
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Public Library of Science
publisher.none.fl_str_mv Public Library of Science
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/51077/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/51077/2/MarciaJardim_IsabelaPitta_etal_IOC_2021.pdf
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
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