Immunotherapy for cancer: effects of iron oxide nanoparticles on polarization of tumor-associated macrophages

Detalhes bibliográficos
Autor(a) principal: Nascimento, Camila Sales
Data de Publicação: 2021
Outros Autores: Alves, Érica Alessandra Rocha, Melo, Celso Pinto de, Oliveira, Rodrigo Corrêa de, Silva, Carlos Eduardo Calzavara
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/53524
Resumo: Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de Pesquisa em Imunologia Celular e Molecular. Belo Horizonte, MG, Brazil
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spelling Nascimento, Camila SalesAlves, Érica Alessandra RochaMelo, Celso Pinto deOliveira, Rodrigo Corrêa deSilva, Carlos Eduardo Calzavara2022-06-27T16:53:22Z2022-06-27T16:53:22Z2021NASCIMENTO, Camila Sales et al. Immunotherapy for cancer: effects of iron oxide nanoparticles on polarization of tumor-associated macrophages. Nanomedicine, v. 16, n. 29, p. 2633-2650, 2021. doi.org/10.2217/nnm-2021-02551743-5889https://www.arca.fiocruz.br/handle/icict/53524org/10.2217/nnm-2021-0255engFuture Medicine LtdImmunotherapy for cancer: effects of iron oxide nanoparticles on polarization of tumor-associated macrophagesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto René Rachou. Grupo de Pesquisa em Imunologia Celular e Molecular. Belo Horizonte, MG, BrazilFundação Oswaldo Cruz. Instituto René Rachou. Grupo de Pesquisa em Imunologia Celular e Molecular. Belo Horizonte, MG, BrazilUniversidade Federal de Pernambuco. Departamento de Física. Grupo de Polímeros Não-Convencionais. Recife, PE, BrazilFundação Oswaldo Cruz. Instituto René Rachou. Grupo de Pesquisa em Imunologia Celular e Molecular. Belo Horizonte, MG, BrazilFundação Oswaldo Cruz. Instituto René Rachou. Grupo de Pesquisa em Imunologia Celular e Molecular. Belo Horizonte, MG, BrazilCancer immunotherapy is the most promising trend in oncology, focusing on helping or activating the patient's immune system to identify and fight against cancer. In the last decade, interest in metabolic reprogramming of tumor-associated macrophages from M2-like phenotype (promoting tumor progression) to M1-like phenotypes (suppressing tumor growth) as a therapeutic strategy against cancer has increased considerably. Iron metabolism has been standing out as a target for the reprogramming of tumor-associated macrophages to M1-like phenotype with therapeutic purposes against cancer. Due to the importance of the iron levels in macrophage polarization states, iron oxide nanoparticles can be used to change the activation state of tumor-associated macrophages for a tumor suppressor phenotype and as an anti-tumor strategy.cancerimmunometabolismimmunotherapyiron oxide nanoparticlesmetabolic reprogramming of tumor-associated macrophagesinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83082https://www.arca.fiocruz.br/bitstream/icict/53524/1/license.txt9193a7c197bc67acd023525e72a03240MD51ORIGINALImmunotherapy for cancer.pdfImmunotherapy for cancer.pdfapplication/pdf10917998https://www.arca.fiocruz.br/bitstream/icict/53524/2/Immunotherapy%20for%20cancer.pdf28676d2484996a774f35185276675b6dMD52icict/535242022-06-27 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dc.title.pt_BR.fl_str_mv Immunotherapy for cancer: effects of iron oxide nanoparticles on polarization of tumor-associated macrophages
title Immunotherapy for cancer: effects of iron oxide nanoparticles on polarization of tumor-associated macrophages
spellingShingle Immunotherapy for cancer: effects of iron oxide nanoparticles on polarization of tumor-associated macrophages
Nascimento, Camila Sales
cancer
immunometabolism
immunotherapy
iron oxide nanoparticles
metabolic reprogramming of tumor-associated macrophages
title_short Immunotherapy for cancer: effects of iron oxide nanoparticles on polarization of tumor-associated macrophages
title_full Immunotherapy for cancer: effects of iron oxide nanoparticles on polarization of tumor-associated macrophages
title_fullStr Immunotherapy for cancer: effects of iron oxide nanoparticles on polarization of tumor-associated macrophages
title_full_unstemmed Immunotherapy for cancer: effects of iron oxide nanoparticles on polarization of tumor-associated macrophages
title_sort Immunotherapy for cancer: effects of iron oxide nanoparticles on polarization of tumor-associated macrophages
author Nascimento, Camila Sales
author_facet Nascimento, Camila Sales
Alves, Érica Alessandra Rocha
Melo, Celso Pinto de
Oliveira, Rodrigo Corrêa de
Silva, Carlos Eduardo Calzavara
author_role author
author2 Alves, Érica Alessandra Rocha
Melo, Celso Pinto de
Oliveira, Rodrigo Corrêa de
Silva, Carlos Eduardo Calzavara
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Nascimento, Camila Sales
Alves, Érica Alessandra Rocha
Melo, Celso Pinto de
Oliveira, Rodrigo Corrêa de
Silva, Carlos Eduardo Calzavara
dc.subject.en.pt_BR.fl_str_mv cancer
immunometabolism
immunotherapy
iron oxide nanoparticles
metabolic reprogramming of tumor-associated macrophages
topic cancer
immunometabolism
immunotherapy
iron oxide nanoparticles
metabolic reprogramming of tumor-associated macrophages
description Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de Pesquisa em Imunologia Celular e Molecular. Belo Horizonte, MG, Brazil
publishDate 2021
dc.date.issued.fl_str_mv 2021
dc.date.accessioned.fl_str_mv 2022-06-27T16:53:22Z
dc.date.available.fl_str_mv 2022-06-27T16:53:22Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv NASCIMENTO, Camila Sales et al. Immunotherapy for cancer: effects of iron oxide nanoparticles on polarization of tumor-associated macrophages. Nanomedicine, v. 16, n. 29, p. 2633-2650, 2021. doi.org/10.2217/nnm-2021-0255
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/53524
dc.identifier.issn.pt_BR.fl_str_mv 1743-5889
dc.identifier.doi.none.fl_str_mv org/10.2217/nnm-2021-0255
identifier_str_mv NASCIMENTO, Camila Sales et al. Immunotherapy for cancer: effects of iron oxide nanoparticles on polarization of tumor-associated macrophages. Nanomedicine, v. 16, n. 29, p. 2633-2650, 2021. doi.org/10.2217/nnm-2021-0255
1743-5889
org/10.2217/nnm-2021-0255
url https://www.arca.fiocruz.br/handle/icict/53524
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Future Medicine Ltd
publisher.none.fl_str_mv Future Medicine Ltd
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/53524/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/53524/2/Immunotherapy%20for%20cancer.pdf
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
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