A terapia hormonal na menopausa e seus efeitos no sistema cardiovascular

• Autor(a) principal: Vieira, Mariana Cysne Frota
• Data de Publicação: 2020
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório do Centro Universitário Braz Cubas
• Texto Completo: https://repositorio.cruzeirodosul.edu.br/handle/123456789/1379
• topic: Terapia hormonal; Menopausa; Doenças cardiovasculares; Climatério; CNPQ::CIENCIAS DA SAUDE::MEDICINA

Introduction: Hormone therapy (HT) is a medication measure that aims to alleviate the symptoms and physiological changes of patients in the climacteric phase. This therapy, like all others in general, has contraindications and, because of this, it must be prescribed for each woman individually, taking into account in a number of factors, from previous pathologies to the age at which menopause occurred. Some studies evaluate the TH relationship and its cardiovascular effects, considering that, with the menopause period, the endogenous estrogen levels in the body refused and the permissions to guarantee protection in the body system. Objectives: This study aims to understand the possible consequences of occasional therapy on the cardiovascular system of patients in menopause, explain the main cardiovascular diseases that can be minimized or exacerbated and describe the best recommendations for the route of administration, showing which period is more favorable for your start. Materials and Methods: This is a bibliographic review research in the form of an exploratory and descriptive study, published in the PubMed, Medline and LILACS databases for the last 10 years (2011-2020) available in English and / or Portuguese. Results: 21 articles were selected using a methodology proposed for this literature review. It should be noted that the therapy is not indicated to be used only in order to combat secondary and cardiovascular infections. Also, make sure that the best TH response for cardiac and vascular events is used when used in women under 60, or as soon as possible at the beginning of menopause. Regarding the form of administration, oral presentations to a patient can be given a greater chance of developing thromboembolic events when compared to non-oral routes. Conclusion: The use of this therapy must be highly individualized, taking into account the particular aspects of each patient, such as the specific symptoms of each woman, in addition to previous diseases associated with, thus, choosing the type of medication to be indicated for each patient situation .