Contaminação de trajeto de biópsia de sarcomas de partes moles em um hospital de câncer da Paraíba
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Tipo de documento: | Trabalho de conclusão de curso |
Idioma: | por |
Título da fonte: | Repositório do Centro Universitário Braz Cubas |
Texto Completo: | https://repositorio.cruzeirodosul.edu.br/handle/123456789/1458 |
Resumo: | Soft tissue sarcomas are rare neoplasms originating from mesenchymal tissues and which have a biopsy as a great ally in the diagnosis, treatment and management of patients affected by these pathologies. Biopsy is still a procedure that generates a lot of doubts among professionals, especially regarding the possible tumor contamination of the procedure. This study aims to identify a rate of tumor contamination in biopsies performed at the reference hospital in the treatment of cancer in Paraíba. The study is a documentary, descriptive and cross-sectional research, with a sample of 10 medical records of patients undergoing biopsy of soft tissue sarcomas in 2019. The variables collected were the age and sex of the patient, the type of biopsy, or histological subtype of the tumor and the presence or absence of tumor contamination in the biopsy path. The data were synchronized and tabulated for final results. This study was approved by the Research Ethics Committee of the Centro Universitário de João Pessoa (UNIPÊ), CAAE: 37862720.8.0000.5176. Of the total medical records available, 50% (n = 5) were female and 50% male. The ages varied between 09 to 35 years old, 20% of them (n = 2) with 12 years old and 30% (n = 3) with 15 years old. 80% (n = 8) of the patients was affected by the pleomorphic sarcoma subtype, 10% (n = 1) liposarcoma and 10% (n = 1) synoviosarcoma.100% (n = 10) of the biopsies were percutaneous. 90% (n = 9) of the biopsies were assessed as not contaminated. The contamination rate of the biopsy pathway of soft tissue sarcomas found in this study was 10%, suggesting the safety of the procedure, as long as performed with the resection of the pathway. |
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Contaminação de trajeto de biópsia de sarcomas de partes moles em um hospital de câncer da ParaíbaBiópsiaContaminaçãoSarcomasTumoralPartes molesCNPQ::CIENCIAS DA SAUDE::MEDICINASoft tissue sarcomas are rare neoplasms originating from mesenchymal tissues and which have a biopsy as a great ally in the diagnosis, treatment and management of patients affected by these pathologies. Biopsy is still a procedure that generates a lot of doubts among professionals, especially regarding the possible tumor contamination of the procedure. This study aims to identify a rate of tumor contamination in biopsies performed at the reference hospital in the treatment of cancer in Paraíba. The study is a documentary, descriptive and cross-sectional research, with a sample of 10 medical records of patients undergoing biopsy of soft tissue sarcomas in 2019. The variables collected were the age and sex of the patient, the type of biopsy, or histological subtype of the tumor and the presence or absence of tumor contamination in the biopsy path. The data were synchronized and tabulated for final results. This study was approved by the Research Ethics Committee of the Centro Universitário de João Pessoa (UNIPÊ), CAAE: 37862720.8.0000.5176. Of the total medical records available, 50% (n = 5) were female and 50% male. The ages varied between 09 to 35 years old, 20% of them (n = 2) with 12 years old and 30% (n = 3) with 15 years old. 80% (n = 8) of the patients was affected by the pleomorphic sarcoma subtype, 10% (n = 1) liposarcoma and 10% (n = 1) synoviosarcoma.100% (n = 10) of the biopsies were percutaneous. 90% (n = 9) of the biopsies were assessed as not contaminated. The contamination rate of the biopsy pathway of soft tissue sarcomas found in this study was 10%, suggesting the safety of the procedure, as long as performed with the resection of the pathway.Os sarcomas de partes moles são neoplasias raras originadas dos tecidos mesenquimais e que possuem a biópsia como grande aliada no diagnóstico, tratamento e manejo dos pacientes acometidos por essas patologias. A biópsia ainda é um procedimento que gera muita dúvida nos profissionais, principalmente no que tange a possível contaminação tumoral do trajeto do procedimento. Esse estudo tem como objetivo identificar a taxa de contaminação tumoral em trajetos de biópsias realizadas num hospital referência no tratamento do câncer na Paraíba. O estudo se trata de uma pesquisa documental, descritiva e transversal, com uma amostra de 10 prontuários de pacientes submetidos à biópsia de sarcomas de partes moles em 2019. As variáveis coletadas foram a idade e o sexo do paciente, o tipo de biópsia, o subtipo histológico do tumor e a presença ou não de contaminação tumoral no trajeto de biópsia. Os dados foram analisados e tabulados para a confecção dos resultados. O presente trabalho foi aprovado pelo Comitê de Ética em Pesquisa do Centro Universitário de João Pessoa (UNIPÊ), CAAE: 37862720.8.0000.5176. Do total de prontuários analisados, 50% (n=5) eram de pacientes do sexo feminino e 50% do sexo masculino. As idades variaram entre 09 a 35 anos, sendo 20% deles (n=2) com 12 anos e 30% (n=3) com 15 anos. 80% (n=8) dos pacientes apresentaram tumores do subtipo sarcoma pleomórfico, 10% (n=1) lipossarcoma e 10% (n=1) sinoviossarcoma.100% (n=10) das biópsias foram percutâneas. 90% (n=9) das biópsias foram consideradas não contaminadas. A taxa contaminação do trajeto de biópsia de sarcomas de partes moles encontrada nesse estudo foi de 10%, sugerindo a segurança do procedimento, desde que realizado com a ressecção do trajeto.Centro Universitário de João PessoaBrasilUNIPÊCardoso, Ricardo Barroshttp://lattes.cnpq.br/6351394168837718Siqueira, André Luís Lopes Gomes dehttp://lattes.cnpq.br/3105841125732217Santos , Ramon Marinho dos2021-02-04T17:05:50Z2021-02-052021-02-04T17:05:50Z2020-12-15info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bachelorThesisapplication/pdfhttps://repositorio.cruzeirodosul.edu.br/handle/123456789/1458porBARRIENTOS-RUIZ, Irene et al. Are biopsy tracts a concern for seeding and local recurrence in sarcomas?. Clinical Orthopaedics and Related Research®, v. 475, n. 2, p. 511-518, 2017. Disponível em: <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5213942/>. Acesso em: 23 out. 2020. BARROS FILHO, T. E. P.; CAMARGO, O. P.; CAMANHO, G. L.. Clínica Ortopédica. Barueri: Manole, 2012. BESSEN, Taryn et al. A population-based study of soft tissue sarcoma incidence and survival in Australia: an analysis of 26,970 cases. Cancer epidemiology, v. 63, p. 101590, 2019. Disponível em: < https://www.sciencedirect.com/science/article/abs/pii/S1877782119301018>. Acesso em: 24 out. 2020. CATES, Justin M. M. The AJCC 8th Edition Staging System for Soft Tissue Sarcoma of the Extremities or Trunk: a cohort study of the seer database.: A Cohort Study of the SEER Database. Journal Of The National Comprehensive Cancer Network, [s.l.], v. 16, n. 2, p. 144-152, fev. 2018. Disponível em: < https://jnccn.org/view/journals/jnccn/16/2/article-p144.xml>. Acesso em: 20 abr. 2020. CHOJNIAK, R. et al. Biópsia percutânea por agulha grossa de tumores de partes moles guiada por tomografia computadorizada: resultados e correlação com análise da peça cirúrgica. Radiologia Brasileira, São Paulo, v. 45, n. 5, p. 259- 262, out. 2012. Disponível em <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100- 39842012000500005&lng=en&nrm=iso>. Acesso em: 20 abr. 2020. COINDRE, J. et al.. Predictive value of grade for metastasis development in the main histologic types of adult soft tissue sarcomas. Cancer, [s.l.], v. 91, n. 10, p. 1914- 1926, 2001. Disponível em: < https://www.ncbi.nlm.nih.gov/pubmed/11346874>. Acesso em: 20 abr. 2020. CORMIER, J. N.; POLLOCK, R. E.. Soft Tissue Sarcomas. Ca: A Cancer Journal for Clinicians, [s.l.], v. 54, n. 2, p. 94-109, 1 mar. 2004. Disponível em: <https://acsjournals.onlinelibrary.wiley.com/doi/full/10.3322/canjclin.54.2.94>. Acesso em: 20 abr. 2020. FERRARI, Andrea et al. Soft tissue sarcoma across the age spectrum: A population‐ based study from the surveillance epidemiology and end results database. Pediatric blood & cancer, v. 57, n. 6, p. 943-949, 2011. Disponível em: < https://onlinelibrary.wiley.com/doi/abs/10.1002/pbc.23252> Acesso em: 25 out. 2020. FERRARI, Andrea; DIRKSEN, Uta; BIELACK, Stefan. Sarcomas of soft tissue andbone. In: Tumors in Adolescents and Young Adults. v. 43, p. 128-141, 2016. Disponível em: < https://www.karger.com/Article/Abstract/447083>. Acesso em: 23 out. 2020. GARCIA, J. et al. Contaminação do trajeto de biópsia em sarcomas primários ósseos. Revista Brasileira de Ortopedia, [s.l.], v. 54, n. 01, p. 033-036, fev. 2019. Disponível em: < https://www.scielo.br/scielo.php?pid=S0102- 36162019000100033&script=sci_arttext&tlng=pt> Acesso em 20 abr. 2020. GOLDBLUM, J. R.; FOLPE, A. L.; WEISS, S. W.. Enzinger and Weiss Soft Tissue Tumours. 6. ed. Philadelphia: Elsevier, 2013. GRIMER, R. et al. Guidelines for the Management of Soft Tissue Sarcomas. Sarcoma, [s.l.], v. 2010, p. 1-15, 2010. Disponível em: < https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903951/#B15>. Acesso em: 20 abr. 2020. HUNG, Giun-Yi et al. Incidence of soft tissue sarcoma in Taiwan: A nationwide population-based study (2007–2013). Cancer epidemiology, v. 60, p. 185-192, 2019. Disponível em: < https://www.sciencedirect.com/science/article/abs/pii/S1877782119300323>. Acesso em: 23 out. 2020. KUMAR, V.; ABBAS, A. K.; ASTER, J. C. Robbins Patologia Básica. 9. ed. Rio de Janeiro: Elsevier, 2013. RIBEIRO, M. B. et al. Estudo histopatológico do trajeto de biópsia de tumores musculoesqueléticos malignos. Acta ortop. bras., São Paulo, v. 17, n. 5, p. 279- 281, 2009. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413- 78522009000500005&lng=en&nrm=iso>. Acesso em 20 abr. 2020. SIQUEIRA, Karina Levy et al . Correlação do tipo de biópsia e sua validade diagnóstica nos tumores músculo-esqueléticos em distintas topografias. Rev. bras. ortop., São Paulo, v. 43, n. 1-2, p. 7-14, Feb. 2008. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102- 36162008000100002&lng=en&nrm=iso>. Acesso em 20 abr. 2020. WORLD HEALTH ORGANIZATION. WHO Classification of Tumours of Soft Tissue and Bone. 4. ed. Lyon: IARC Press, 2013. ZAHM, S. H.; FRAUMENI JUNIOR, J. F.. The Epidemiology of Soft Tissue Sarcoma. Seminars In Oncology, Rockville, v. 24, n. 5, p. 504-514, out. 1997. Disponível em: < https://www.ncbi.nlm.nih.gov/pubmed/9344316>. Acesso em: 20 abr. 2020.info:eu-repo/semantics/openAccessreponame:Repositório do Centro Universitário Braz Cubasinstname:Centro Universitário Braz Cubas (CUB)instacron:CUB2021-02-04T17:06:31Zoai:repositorio.cruzeirodosul.edu.br:123456789/1458Repositório InstitucionalPUBhttps://repositorio.brazcubas.edu.br/oai/requestbibli@brazcubas.edu.bropendoar:2021-02-04T17:06:31Repositório do Centro Universitário Braz Cubas - Centro Universitário Braz Cubas (CUB)false |
dc.title.none.fl_str_mv |
Contaminação de trajeto de biópsia de sarcomas de partes moles em um hospital de câncer da Paraíba |
title |
Contaminação de trajeto de biópsia de sarcomas de partes moles em um hospital de câncer da Paraíba |
spellingShingle |
Contaminação de trajeto de biópsia de sarcomas de partes moles em um hospital de câncer da Paraíba Santos , Ramon Marinho dos Biópsia Contaminação Sarcomas Tumoral Partes moles CNPQ::CIENCIAS DA SAUDE::MEDICINA |
title_short |
Contaminação de trajeto de biópsia de sarcomas de partes moles em um hospital de câncer da Paraíba |
title_full |
Contaminação de trajeto de biópsia de sarcomas de partes moles em um hospital de câncer da Paraíba |
title_fullStr |
Contaminação de trajeto de biópsia de sarcomas de partes moles em um hospital de câncer da Paraíba |
title_full_unstemmed |
Contaminação de trajeto de biópsia de sarcomas de partes moles em um hospital de câncer da Paraíba |
title_sort |
Contaminação de trajeto de biópsia de sarcomas de partes moles em um hospital de câncer da Paraíba |
author |
Santos , Ramon Marinho dos |
author_facet |
Santos , Ramon Marinho dos |
author_role |
author |
dc.contributor.none.fl_str_mv |
Cardoso, Ricardo Barros http://lattes.cnpq.br/6351394168837718 Siqueira, André Luís Lopes Gomes de http://lattes.cnpq.br/3105841125732217 |
dc.contributor.author.fl_str_mv |
Santos , Ramon Marinho dos |
dc.subject.por.fl_str_mv |
Biópsia Contaminação Sarcomas Tumoral Partes moles CNPQ::CIENCIAS DA SAUDE::MEDICINA |
topic |
Biópsia Contaminação Sarcomas Tumoral Partes moles CNPQ::CIENCIAS DA SAUDE::MEDICINA |
description |
Soft tissue sarcomas are rare neoplasms originating from mesenchymal tissues and which have a biopsy as a great ally in the diagnosis, treatment and management of patients affected by these pathologies. Biopsy is still a procedure that generates a lot of doubts among professionals, especially regarding the possible tumor contamination of the procedure. This study aims to identify a rate of tumor contamination in biopsies performed at the reference hospital in the treatment of cancer in Paraíba. The study is a documentary, descriptive and cross-sectional research, with a sample of 10 medical records of patients undergoing biopsy of soft tissue sarcomas in 2019. The variables collected were the age and sex of the patient, the type of biopsy, or histological subtype of the tumor and the presence or absence of tumor contamination in the biopsy path. The data were synchronized and tabulated for final results. This study was approved by the Research Ethics Committee of the Centro Universitário de João Pessoa (UNIPÊ), CAAE: 37862720.8.0000.5176. Of the total medical records available, 50% (n = 5) were female and 50% male. The ages varied between 09 to 35 years old, 20% of them (n = 2) with 12 years old and 30% (n = 3) with 15 years old. 80% (n = 8) of the patients was affected by the pleomorphic sarcoma subtype, 10% (n = 1) liposarcoma and 10% (n = 1) synoviosarcoma.100% (n = 10) of the biopsies were percutaneous. 90% (n = 9) of the biopsies were assessed as not contaminated. The contamination rate of the biopsy pathway of soft tissue sarcomas found in this study was 10%, suggesting the safety of the procedure, as long as performed with the resection of the pathway. |
publishDate |
2020 |
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2020-12-15 2021-02-04T17:05:50Z 2021-02-05 2021-02-04T17:05:50Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/bachelorThesis |
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https://repositorio.cruzeirodosul.edu.br/handle/123456789/1458 |
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https://repositorio.cruzeirodosul.edu.br/handle/123456789/1458 |
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por |
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por |
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BARRIENTOS-RUIZ, Irene et al. Are biopsy tracts a concern for seeding and local recurrence in sarcomas?. Clinical Orthopaedics and Related Research®, v. 475, n. 2, p. 511-518, 2017. Disponível em: <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5213942/>. Acesso em: 23 out. 2020. BARROS FILHO, T. E. P.; CAMARGO, O. P.; CAMANHO, G. L.. Clínica Ortopédica. Barueri: Manole, 2012. BESSEN, Taryn et al. A population-based study of soft tissue sarcoma incidence and survival in Australia: an analysis of 26,970 cases. Cancer epidemiology, v. 63, p. 101590, 2019. Disponível em: < https://www.sciencedirect.com/science/article/abs/pii/S1877782119301018>. Acesso em: 24 out. 2020. CATES, Justin M. M. The AJCC 8th Edition Staging System for Soft Tissue Sarcoma of the Extremities or Trunk: a cohort study of the seer database.: A Cohort Study of the SEER Database. Journal Of The National Comprehensive Cancer Network, [s.l.], v. 16, n. 2, p. 144-152, fev. 2018. Disponível em: < https://jnccn.org/view/journals/jnccn/16/2/article-p144.xml>. Acesso em: 20 abr. 2020. CHOJNIAK, R. et al. Biópsia percutânea por agulha grossa de tumores de partes moles guiada por tomografia computadorizada: resultados e correlação com análise da peça cirúrgica. Radiologia Brasileira, São Paulo, v. 45, n. 5, p. 259- 262, out. 2012. Disponível em <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100- 39842012000500005&lng=en&nrm=iso>. Acesso em: 20 abr. 2020. COINDRE, J. et al.. Predictive value of grade for metastasis development in the main histologic types of adult soft tissue sarcomas. Cancer, [s.l.], v. 91, n. 10, p. 1914- 1926, 2001. Disponível em: < https://www.ncbi.nlm.nih.gov/pubmed/11346874>. Acesso em: 20 abr. 2020. CORMIER, J. N.; POLLOCK, R. E.. Soft Tissue Sarcomas. Ca: A Cancer Journal for Clinicians, [s.l.], v. 54, n. 2, p. 94-109, 1 mar. 2004. Disponível em: <https://acsjournals.onlinelibrary.wiley.com/doi/full/10.3322/canjclin.54.2.94>. Acesso em: 20 abr. 2020. FERRARI, Andrea et al. Soft tissue sarcoma across the age spectrum: A population‐ based study from the surveillance epidemiology and end results database. Pediatric blood & cancer, v. 57, n. 6, p. 943-949, 2011. Disponível em: < https://onlinelibrary.wiley.com/doi/abs/10.1002/pbc.23252> Acesso em: 25 out. 2020. FERRARI, Andrea; DIRKSEN, Uta; BIELACK, Stefan. Sarcomas of soft tissue andbone. In: Tumors in Adolescents and Young Adults. v. 43, p. 128-141, 2016. Disponível em: < https://www.karger.com/Article/Abstract/447083>. Acesso em: 23 out. 2020. GARCIA, J. et al. Contaminação do trajeto de biópsia em sarcomas primários ósseos. Revista Brasileira de Ortopedia, [s.l.], v. 54, n. 01, p. 033-036, fev. 2019. Disponível em: < https://www.scielo.br/scielo.php?pid=S0102- 36162019000100033&script=sci_arttext&tlng=pt> Acesso em 20 abr. 2020. GOLDBLUM, J. R.; FOLPE, A. L.; WEISS, S. W.. Enzinger and Weiss Soft Tissue Tumours. 6. ed. Philadelphia: Elsevier, 2013. GRIMER, R. et al. Guidelines for the Management of Soft Tissue Sarcomas. Sarcoma, [s.l.], v. 2010, p. 1-15, 2010. Disponível em: < https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903951/#B15>. Acesso em: 20 abr. 2020. HUNG, Giun-Yi et al. Incidence of soft tissue sarcoma in Taiwan: A nationwide population-based study (2007–2013). Cancer epidemiology, v. 60, p. 185-192, 2019. Disponível em: < https://www.sciencedirect.com/science/article/abs/pii/S1877782119300323>. Acesso em: 23 out. 2020. KUMAR, V.; ABBAS, A. K.; ASTER, J. C. Robbins Patologia Básica. 9. ed. Rio de Janeiro: Elsevier, 2013. RIBEIRO, M. B. et al. Estudo histopatológico do trajeto de biópsia de tumores musculoesqueléticos malignos. Acta ortop. bras., São Paulo, v. 17, n. 5, p. 279- 281, 2009. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413- 78522009000500005&lng=en&nrm=iso>. Acesso em 20 abr. 2020. SIQUEIRA, Karina Levy et al . Correlação do tipo de biópsia e sua validade diagnóstica nos tumores músculo-esqueléticos em distintas topografias. Rev. bras. ortop., São Paulo, v. 43, n. 1-2, p. 7-14, Feb. 2008. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102- 36162008000100002&lng=en&nrm=iso>. Acesso em 20 abr. 2020. WORLD HEALTH ORGANIZATION. WHO Classification of Tumours of Soft Tissue and Bone. 4. ed. Lyon: IARC Press, 2013. ZAHM, S. H.; FRAUMENI JUNIOR, J. F.. The Epidemiology of Soft Tissue Sarcoma. Seminars In Oncology, Rockville, v. 24, n. 5, p. 504-514, out. 1997. Disponível em: < https://www.ncbi.nlm.nih.gov/pubmed/9344316>. Acesso em: 20 abr. 2020. |
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