Treinamento de força com restrição de fluxo sanguíneo: uma abordagem imunológica e psicobiológica sobre a pressão da braçadeira.

Detalhes bibliográficos
Autor(a) principal: Lima, Fabio Rocha de
Data de Publicação: 2018
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Repositório do Centro Universitário Braz Cubas
Texto Completo: https://repositorio.cruzeirodosul.edu.br/handle/123456789/281
Resumo: Strength training with blood flow restriction (STBFR) has been pointed out as an effective method to promote hypertrophy and increase strength. However, there is no need for studies to discuss how manipulation of cuff pressure can influence oxidative stress and apoptosis of circulating lymphocytes and neutrophils. Objective: To verify the acute and chronic effect of TFRFS at different pressures on circulating lymphocyte and neutrophil apoptosis, plasma oxidative stress and on psychobiological parameters. Materials and methods: Twenty-seven male subjects (20-25 years old) were recruited, who were randomly divided into three groups: Group without restriction (SR); Group with partial restriction (RP); Group with total restriction (RT). The intensity for the SR group was 75% of 1RM, and 20% of 1RM for RP and RT, differing only in the cuff pressure. A bilateral elbow flexion exercise was used, and the sessions occurred 3 times a week for 10 weeks. Results: The mitochondrial neutrophil membrane potential decreased after exercise in the three groups, whereas in lymphocytes decreased only in the SR group. The caspase-3 activity of neutrophils increased in the SR and RT groups, whereas in lymphocytes it increased only in the SR group. The iron reduction test (FRAP) and reduced glutathione (GSH) decreased only in the SR and RT groups. Oxidated glutathione (GSSG), carbonylated protein and thiobarbituric acid reaction (TBARS) increased in the SR and RT groups. The RP group had the highest effort values when compared to the SR group and the RT group. For the pain level, the group RP and RT presented the highest values when compared to the SR group. The level of discomfort was higher in the RT group when compared to the RP and SR group. In the mood state, the tension levels reduced significantly after exercise in the SR and RT groups. For depression, the SR group presented the highest values before and after exercise when compared to the two moments (before and after) of the SR group. For rabies, there was a significant reduction after exercise in the SR group. Pre and post exercise strength values were higher in the PR group when compared to SR and RT groups. Fatigue scores were higher at the pre- and post-exercise moments in the SR and RT groups when compared to the PR group. Conclusion: It can be concluded that TFRFS with total restriction promotes apoptosis of neutrophils, but not lymphocytes. Pressure manipulation of the cuff can further influence oxidative stress, both acute and chronic. Psychobiological variables indicate that the blood flow restriction strategy may be efficient to increase adherence to exercise, but that pressure should be selected with caution, since higher pressures interfere with important variables to determine the continuity of exercise.
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spelling Treinamento de força com restrição de fluxo sanguíneo: uma abordagem imunológica e psicobiológica sobre a pressão da braçadeira.Strength training with blood flow restriction: an immunological and psychobiological approach to cuff pressure.Kaatsu-trainingNeutrófilosLinfócitosPlasmaPsicobiologiaCNPQ::CIENCIAS DA SAUDEStrength training with blood flow restriction (STBFR) has been pointed out as an effective method to promote hypertrophy and increase strength. However, there is no need for studies to discuss how manipulation of cuff pressure can influence oxidative stress and apoptosis of circulating lymphocytes and neutrophils. Objective: To verify the acute and chronic effect of TFRFS at different pressures on circulating lymphocyte and neutrophil apoptosis, plasma oxidative stress and on psychobiological parameters. Materials and methods: Twenty-seven male subjects (20-25 years old) were recruited, who were randomly divided into three groups: Group without restriction (SR); Group with partial restriction (RP); Group with total restriction (RT). The intensity for the SR group was 75% of 1RM, and 20% of 1RM for RP and RT, differing only in the cuff pressure. A bilateral elbow flexion exercise was used, and the sessions occurred 3 times a week for 10 weeks. Results: The mitochondrial neutrophil membrane potential decreased after exercise in the three groups, whereas in lymphocytes decreased only in the SR group. The caspase-3 activity of neutrophils increased in the SR and RT groups, whereas in lymphocytes it increased only in the SR group. The iron reduction test (FRAP) and reduced glutathione (GSH) decreased only in the SR and RT groups. Oxidated glutathione (GSSG), carbonylated protein and thiobarbituric acid reaction (TBARS) increased in the SR and RT groups. The RP group had the highest effort values when compared to the SR group and the RT group. For the pain level, the group RP and RT presented the highest values when compared to the SR group. The level of discomfort was higher in the RT group when compared to the RP and SR group. In the mood state, the tension levels reduced significantly after exercise in the SR and RT groups. For depression, the SR group presented the highest values before and after exercise when compared to the two moments (before and after) of the SR group. For rabies, there was a significant reduction after exercise in the SR group. Pre and post exercise strength values were higher in the PR group when compared to SR and RT groups. Fatigue scores were higher at the pre- and post-exercise moments in the SR and RT groups when compared to the PR group. Conclusion: It can be concluded that TFRFS with total restriction promotes apoptosis of neutrophils, but not lymphocytes. Pressure manipulation of the cuff can further influence oxidative stress, both acute and chronic. Psychobiological variables indicate that the blood flow restriction strategy may be efficient to increase adherence to exercise, but that pressure should be selected with caution, since higher pressures interfere with important variables to determine the continuity of exercise.O treinamento de força com restrição de fluxo sanguíneo (TFRFS) tem sido apontado como sendo um método eficaz para promover hipertrofia e o aumento da força. Entretanto, carecem de estudos que discutam como a manipulação da pressão da braçadeira pode influenciar no estresse oxidativo e na apoptose de linfócitos e neutrófilos circulantes. Objetivo: Verificar o efeito agudo e crônico que o TFRFS em diferentes pressões tem na apoptose de linfócitos e neutrófilos circulantes, estresse oxidativo plasmático e em parâmetros psicobiológicos. Materiais e métodos: Foram recrutados 27 sujeitos do sexo masculino (20-25 anos), que foram divididos aleatoriamente em três grupos: Grupo sem restrição (SR); Grupo com restrição parcial (RP); Grupo com restrição total (RT). A intensidade para o grupo SR foi de 75% de 1RM, e 20% de 1RM para RP e RT, diferenciando apenas na pressão da braçadeira. Foi utilizado um exercício de flexão de cotovelo bilateral, e as sessões ocorreram 3 vezes por semana, durante 10 semanas. Resultados: O potencial de membrana mitocondrial de neutrófilos diminuiu após o exercício nos três grupos, enquanto que em linfócitos diminuiu apenas no grupo SR. A atividade da caspase-3 de neutrófilos aumentou no grupo SR e RT, enquanto que em linfócitos aumentou somente no grupo SR. O ensaio de redução de ferro (FRAP) e de glutationa reduzida (GSH) diminuiu somente no grupo SR e RT. A glutationa oxidada (GSSG), proteína carbonilada e reação ao ácido tiobarbitúrico (TBARS) aumentou nos grupos SR e RT. O grupo RP apresentou os maiores valores de esforço quando comparado ao grupo SR e ao grupo RT. Para o nível de dor, o grupo RP e RT apresentaram os maiores valores quando comparados ao grupo SR. O nível de desconforto foi maior no grupo RT quando comparado ao grupo RP e SR.No estado de humor, os níveis de tensão reduziram significativamente após o exercício nos grupos SR e RT. Para a depressão, o grupo SR apresentou os maiores valores antes e após o exercício quando comparado aos dois momentos (antes e após) do grupo SR. Para a raiva, houve redução significativa após o exercício no grupo SR. Os valores de vigor do momento pré e pós-exercício foram maiores no grupo RP quando comparados aos grupos SR e RT. Os escores de fadiga foram maiores no momento pré e pós-exercício nos grupos SR e RT quando comparados ao grupo RP. Conclusão: Pode-se concluir que o TFRFS com restrição total promove a apoptose de neutrófilos, mas não de linfócitos. A manipulação da pressão da braçadeira pode ainda influenciar no estresse oxidativo, tanto no momento agudo quanto crônico. As variáveis psicobiológicas indicam que a estratégia de restrição de fluxo sanguíneo pode ser eficiente para aumentar a aderência ao exercício, mas que a pressão deve ser selecionada com cautela, pois pressões mais elevadas interferem em variáveis importantes para determinar a continuidade ao exercício.Universidade Cruzeiro do SulBrasilMestrado interdisciplinar em ciências da saúdeCruzeiro do SulOtton, Rosemari74531611934http://lattes.cnpq.br/1164500211646058Otton, Rosemari74531611934http://lattes.cnpq.br/1164500211646058Lima, Fabio Rocha de2020-01-22T19:10:22Z20202020-01-22T19:10:22Z2018-12-07info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfLIMA, F.R. Treinamento de força com restrição de fluxo sanguíneo: uma abordagem imunológica e psicobiológica sobre a pressão da braçadeira. Dissertação (Mestrado em Ciências da Saúde) - Universidade Cruzeiro do Sul, São Paulo, 2018.https://repositorio.cruzeirodosul.edu.br/handle/123456789/281porinfo:eu-repo/semantics/openAccessreponame:Repositório do Centro Universitário Braz Cubasinstname:Centro Universitário Braz Cubas (CUB)instacron:CUB2020-03-27T20:15:13Zoai:repositorio.cruzeirodosul.edu.br:123456789/281Repositório InstitucionalPUBhttps://repositorio.brazcubas.edu.br/oai/requestbibli@brazcubas.edu.bropendoar:2020-03-27T20:15:13Repositório do Centro Universitário Braz Cubas - Centro Universitário Braz Cubas (CUB)false
dc.title.none.fl_str_mv Treinamento de força com restrição de fluxo sanguíneo: uma abordagem imunológica e psicobiológica sobre a pressão da braçadeira.
Strength training with blood flow restriction: an immunological and psychobiological approach to cuff pressure.
title Treinamento de força com restrição de fluxo sanguíneo: uma abordagem imunológica e psicobiológica sobre a pressão da braçadeira.
spellingShingle Treinamento de força com restrição de fluxo sanguíneo: uma abordagem imunológica e psicobiológica sobre a pressão da braçadeira.
Lima, Fabio Rocha de
Kaatsu-training
Neutrófilos
Linfócitos
Plasma
Psicobiologia
CNPQ::CIENCIAS DA SAUDE
title_short Treinamento de força com restrição de fluxo sanguíneo: uma abordagem imunológica e psicobiológica sobre a pressão da braçadeira.
title_full Treinamento de força com restrição de fluxo sanguíneo: uma abordagem imunológica e psicobiológica sobre a pressão da braçadeira.
title_fullStr Treinamento de força com restrição de fluxo sanguíneo: uma abordagem imunológica e psicobiológica sobre a pressão da braçadeira.
title_full_unstemmed Treinamento de força com restrição de fluxo sanguíneo: uma abordagem imunológica e psicobiológica sobre a pressão da braçadeira.
title_sort Treinamento de força com restrição de fluxo sanguíneo: uma abordagem imunológica e psicobiológica sobre a pressão da braçadeira.
author Lima, Fabio Rocha de
author_facet Lima, Fabio Rocha de
author_role author
dc.contributor.none.fl_str_mv Otton, Rosemari
74531611934
http://lattes.cnpq.br/1164500211646058
Otton, Rosemari
74531611934
http://lattes.cnpq.br/1164500211646058
dc.contributor.author.fl_str_mv Lima, Fabio Rocha de
dc.subject.por.fl_str_mv Kaatsu-training
Neutrófilos
Linfócitos
Plasma
Psicobiologia
CNPQ::CIENCIAS DA SAUDE
topic Kaatsu-training
Neutrófilos
Linfócitos
Plasma
Psicobiologia
CNPQ::CIENCIAS DA SAUDE
description Strength training with blood flow restriction (STBFR) has been pointed out as an effective method to promote hypertrophy and increase strength. However, there is no need for studies to discuss how manipulation of cuff pressure can influence oxidative stress and apoptosis of circulating lymphocytes and neutrophils. Objective: To verify the acute and chronic effect of TFRFS at different pressures on circulating lymphocyte and neutrophil apoptosis, plasma oxidative stress and on psychobiological parameters. Materials and methods: Twenty-seven male subjects (20-25 years old) were recruited, who were randomly divided into three groups: Group without restriction (SR); Group with partial restriction (RP); Group with total restriction (RT). The intensity for the SR group was 75% of 1RM, and 20% of 1RM for RP and RT, differing only in the cuff pressure. A bilateral elbow flexion exercise was used, and the sessions occurred 3 times a week for 10 weeks. Results: The mitochondrial neutrophil membrane potential decreased after exercise in the three groups, whereas in lymphocytes decreased only in the SR group. The caspase-3 activity of neutrophils increased in the SR and RT groups, whereas in lymphocytes it increased only in the SR group. The iron reduction test (FRAP) and reduced glutathione (GSH) decreased only in the SR and RT groups. Oxidated glutathione (GSSG), carbonylated protein and thiobarbituric acid reaction (TBARS) increased in the SR and RT groups. The RP group had the highest effort values when compared to the SR group and the RT group. For the pain level, the group RP and RT presented the highest values when compared to the SR group. The level of discomfort was higher in the RT group when compared to the RP and SR group. In the mood state, the tension levels reduced significantly after exercise in the SR and RT groups. For depression, the SR group presented the highest values before and after exercise when compared to the two moments (before and after) of the SR group. For rabies, there was a significant reduction after exercise in the SR group. Pre and post exercise strength values were higher in the PR group when compared to SR and RT groups. Fatigue scores were higher at the pre- and post-exercise moments in the SR and RT groups when compared to the PR group. Conclusion: It can be concluded that TFRFS with total restriction promotes apoptosis of neutrophils, but not lymphocytes. Pressure manipulation of the cuff can further influence oxidative stress, both acute and chronic. Psychobiological variables indicate that the blood flow restriction strategy may be efficient to increase adherence to exercise, but that pressure should be selected with caution, since higher pressures interfere with important variables to determine the continuity of exercise.
publishDate 2018
dc.date.none.fl_str_mv 2018-12-07
2020-01-22T19:10:22Z
2020
2020-01-22T19:10:22Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv LIMA, F.R. Treinamento de força com restrição de fluxo sanguíneo: uma abordagem imunológica e psicobiológica sobre a pressão da braçadeira. Dissertação (Mestrado em Ciências da Saúde) - Universidade Cruzeiro do Sul, São Paulo, 2018.
https://repositorio.cruzeirodosul.edu.br/handle/123456789/281
identifier_str_mv LIMA, F.R. Treinamento de força com restrição de fluxo sanguíneo: uma abordagem imunológica e psicobiológica sobre a pressão da braçadeira. Dissertação (Mestrado em Ciências da Saúde) - Universidade Cruzeiro do Sul, São Paulo, 2018.
url https://repositorio.cruzeirodosul.edu.br/handle/123456789/281
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Cruzeiro do Sul
Brasil
Mestrado interdisciplinar em ciências da saúde
Cruzeiro do Sul
publisher.none.fl_str_mv Universidade Cruzeiro do Sul
Brasil
Mestrado interdisciplinar em ciências da saúde
Cruzeiro do Sul
dc.source.none.fl_str_mv reponame:Repositório do Centro Universitário Braz Cubas
instname:Centro Universitário Braz Cubas (CUB)
instacron:CUB
instname_str Centro Universitário Braz Cubas (CUB)
instacron_str CUB
institution CUB
reponame_str Repositório do Centro Universitário Braz Cubas
collection Repositório do Centro Universitário Braz Cubas
repository.name.fl_str_mv Repositório do Centro Universitário Braz Cubas - Centro Universitário Braz Cubas (CUB)
repository.mail.fl_str_mv bibli@brazcubas.edu.br
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