Prevalência de portadores da doença celíaca em laboratório de patologia de um serviço privado

• Autor(a) principal: Mascarenhas, Ana Vitória Mangabeira
• Data de Publicação: 2020
• Tipo de documento: Trabalho de conclusão de curso
• Idioma: por
• Título da fonte: Repositório do Centro Universitário Braz Cubas
• Texto Completo: https://repositorio.cruzeirodosul.edu.br/handle/123456789/1294
• topic: Doença Celíaca; Prevalência; Biópsia de intestino delgado; CNPQ::CIÊNCIAS DA SAÚDE::MEDICINA

Celiac disease (CD) is an enteropathy characterized by permanent intolerance to gluten and triggered by autoimmune mechanisms in genetically predisposed individuals. For diagnosis, a combination of clinical, serological and histological findings is performed, with small intestine biopsy being the gold standard in most parts of the world. The treatment constitutes the realization of the gluten exclusion diet. Currently, CD has na important prevalence and affects about 1% of the population in many parts of the world. In Brazil, a high prevalence is estimated, which indicates the need for studies with greater knowledge and dissemination of disease. The present study proposes to analyze the prevalence of celiac disease in a pathological laboratory of a private service in the city of João Pessoa (PB). This is a cross-sectional analytical descriptive documentary research, with a quantitative approach. Duodenal biopsy reports from the upper gastrointestinal endoscopy procedure were reviewed over a period of 20 years. Out of a total of 1045 biopsies, 23 patients were diagnosed with celiac disease, aged 0-44 years, of both sexes. The research was approved by the Research Ethics Committee of the Centro Universitário de João Pessoa, Certificate of Presentation for Ethical Appreciation (CAAE): 26961119.3.0000.5176, Opinion Number: 4.020.344. A higher prevalence of celiac disease was found in females, as well as in the pediatric age group. The descriptive analysis showed a slight increase in the number of diagnoses over the years. Therefore, it is speculated that the disease is underdiagnosed in our country. There is a need for further studies on the prevalence in Paraiba, and greater knowledge about celiac disease and the epidemiological profile.