Motivos para a descontinuação da profilaxia pré exposição ao HIV

• Autor(a) principal: Barros Neto, Ruy Formiga
• Data de Publicação: 2020
• Tipo de documento: Trabalho de conclusão de curso
• Idioma: por
• Título da fonte: Repositório do Centro Universitário Braz Cubas
• Texto Completo: https://repositorio.cruzeirodosul.edu.br/handle/123456789/1415
• topic: Profilaxia pré-exposição; Adesão; Descontinuação; CNPQ::CIENCIAS DA SAUDE::MEDICINA

Background: Introduction: Pre-exposure prophylaxis (PrEP) consists of the daily oral use of a pill that combines two drugs and, depending on the patient's adherence to prophylaxis, promotes a reduction in the risk of infection by the human iodine deficiency virus (HIV). There are several reasons in the literature to discontinue the use of PrEP. Objectives: To describe the reasons for discontinuing pre-exposure prophylaxis to the HIV virus among patients included in PrEP in the literature in the last 3 years. Materials and methods: Exploratory and descriptive bibliographic research, carried out on secondary sources of the topic under study. Data collection was carried out during the months of April and May 2020. Articles from the last 3 years (2017 - 2020), in English and Portuguese, were included. Result: 15 articles were selected. It was analyzed that the reasons for discontinuation are diverse, including self-perception and low risk for HIV infection and medical insurance costs. Regarding the sociodemographic profile, the studies that were part of this review have different aspects; some were carried out in countries with a different population socially, culturally and economically. Regarding the adverse effects that may become barriers to full adherence and longitudinal continuity of prophylaxis, the literature is very vague. Conclusion: Adherence and longitudinality are necessary principles for the success of Pre-Exposure Prophylaxis and interventions need to be developed as barriers such as low risk of self-perceived HIV infection arise.