Advances in knowledge about induced tooth movement Part 1: the osteocytes

Detalhes bibliográficos
Autor(a) principal: Consolaro,Alberto
Data de Publicação: 2012
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Dental Press Journal of Orthodontics
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2176-94512012000300004
Resumo: Osteoblasts and clasts were primary targets for the understanding of bone biopathology. In recent years, evidence has shifted attention to the osteocytes. The biology of induced tooth movement and jaw orthopedics should research the role of osteocytes and the specific effects of mediators such as RANKL and sclerostin. The sclerostin represents a regulatory molecule: When more bone is necessary, osteocytes release less sclerostin, when it is necessary to inhibit bone formation, osteocytes release more sclerostin. RANKL is connected to local osteoclastogenesis in order to have more cells capable of reabsorbing the mineralized matrix. New therapeutic ways of controlling the metabolic bone diseases have been targeted at these mediators.
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spelling Advances in knowledge about induced tooth movement Part 1: the osteocytesOsteocytesMechanotransductionTooth movementSclerostinRANKLOsteoblasts and clasts were primary targets for the understanding of bone biopathology. In recent years, evidence has shifted attention to the osteocytes. The biology of induced tooth movement and jaw orthopedics should research the role of osteocytes and the specific effects of mediators such as RANKL and sclerostin. The sclerostin represents a regulatory molecule: When more bone is necessary, osteocytes release less sclerostin, when it is necessary to inhibit bone formation, osteocytes release more sclerostin. RANKL is connected to local osteoclastogenesis in order to have more cells capable of reabsorbing the mineralized matrix. New therapeutic ways of controlling the metabolic bone diseases have been targeted at these mediators.Dental Press International2012-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2176-94512012000300004Dental Press Journal of Orthodontics v.17 n.3 2012reponame:Dental Press Journal of Orthodonticsinstname:Dental Press International (DPI)instacron:DPI10.1590/S2176-94512012000300004info:eu-repo/semantics/openAccessConsolaro,Albertoeng2012-08-16T00:00:00Zoai:scielo:S2176-94512012000300004Revistahttp://www.scielo.br/dpjoONGhttps://old.scielo.br/oai/scielo-oai.phpartigos@dentalpress.com.br||davidnormando@hotmail.com2177-67092176-9451opendoar:2012-08-16T00:00Dental Press Journal of Orthodontics - Dental Press International (DPI)false
dc.title.none.fl_str_mv Advances in knowledge about induced tooth movement Part 1: the osteocytes
title Advances in knowledge about induced tooth movement Part 1: the osteocytes
spellingShingle Advances in knowledge about induced tooth movement Part 1: the osteocytes
Consolaro,Alberto
Osteocytes
Mechanotransduction
Tooth movement
Sclerostin
RANKL
title_short Advances in knowledge about induced tooth movement Part 1: the osteocytes
title_full Advances in knowledge about induced tooth movement Part 1: the osteocytes
title_fullStr Advances in knowledge about induced tooth movement Part 1: the osteocytes
title_full_unstemmed Advances in knowledge about induced tooth movement Part 1: the osteocytes
title_sort Advances in knowledge about induced tooth movement Part 1: the osteocytes
author Consolaro,Alberto
author_facet Consolaro,Alberto
author_role author
dc.contributor.author.fl_str_mv Consolaro,Alberto
dc.subject.por.fl_str_mv Osteocytes
Mechanotransduction
Tooth movement
Sclerostin
RANKL
topic Osteocytes
Mechanotransduction
Tooth movement
Sclerostin
RANKL
description Osteoblasts and clasts were primary targets for the understanding of bone biopathology. In recent years, evidence has shifted attention to the osteocytes. The biology of induced tooth movement and jaw orthopedics should research the role of osteocytes and the specific effects of mediators such as RANKL and sclerostin. The sclerostin represents a regulatory molecule: When more bone is necessary, osteocytes release less sclerostin, when it is necessary to inhibit bone formation, osteocytes release more sclerostin. RANKL is connected to local osteoclastogenesis in order to have more cells capable of reabsorbing the mineralized matrix. New therapeutic ways of controlling the metabolic bone diseases have been targeted at these mediators.
publishDate 2012
dc.date.none.fl_str_mv 2012-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2176-94512012000300004
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2176-94512012000300004
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S2176-94512012000300004
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Dental Press International
publisher.none.fl_str_mv Dental Press International
dc.source.none.fl_str_mv Dental Press Journal of Orthodontics v.17 n.3 2012
reponame:Dental Press Journal of Orthodontics
instname:Dental Press International (DPI)
instacron:DPI
instname_str Dental Press International (DPI)
instacron_str DPI
institution DPI
reponame_str Dental Press Journal of Orthodontics
collection Dental Press Journal of Orthodontics
repository.name.fl_str_mv Dental Press Journal of Orthodontics - Dental Press International (DPI)
repository.mail.fl_str_mv artigos@dentalpress.com.br||davidnormando@hotmail.com
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