Bilateral pyelonephritis due to Escherichia coli infection in a captive jaguar (Panthera onca)

• Autor(a) principal: Wronski,Julia G.
• Data de Publicação: 2020
• Outros Autores: Argenta,Fernando F., Raiter,Jacqueline, Ehlers,Luiza P., Sala,Rafaella D.V., Siqueira,Franciele M., Cardoso,Diego F., Sonne,Luciana, Pavarini,Saulo P.
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Pesquisa Veterinária Brasileira (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2020000700554
• topic: Bilateral pyelonephritis; Escherichia coli; infection; captive jaguar; Panthera onca; extraintestinal pathogenic E. coli; uropathogenic E. coli; pyelonephritis; uterine leiomyoma; wildlife animals

ABSTRACT: Extraintestinal pathogenic Escherichia coli (ExPEC) is a highly diverse pathotype of E. coli which colonizes the intestine, and it is considered an important etiological agent associated with bacteremia and other systemic infections, among them urinary tract infection. Retrospective studies evaluating morbidity and mortality of nondomestic felids have demonstrated that urinary tract diseases are among the main causes of death for geriatric animals. Also, mesenchymal neoplasms of the uterus are common in wild felids, and they possess variable morphologic characteristics related to invasiveness and malignancy. This report describes a case of bilateral pyelonephritis due to extraintestinal uropathogenic E. coli infection in a captive jaguar (Panthera onca). The diagnosis was confirmed through pathological, bacterial and immunohistochemical findings. According to molecular analysis, this E. coli strain was classified in the phylogroup F, possessing the following virulence-associated genes: usp, cnf-1, hlyA, papC and sfa. Additionally, this E. coli was highly resistant to β-lactams and first-generation cephalosporin. This jaguar also presented a uterine leiomyoma with distinct distribution, and severe degenerative articular disease, both of them described as frequently seen lesions in geriatric animals from the Panthera genus.