Determination of the reference interval for the activity of N-Acetyl-β-D-Glucosaminidase (NAG) in urine of healthy dogs
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2018 |
| Outros Autores: | , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Pesquisa Veterinária Brasileira (Online) |
| Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2018000801685 |
Resumo: | ABSTRACT: The diagnosis of acute kidney injury by evaluating the activity of urinary enzymes is an important tool especially for its precocity in relation to methods of assessment of renal function considered late as the installation of injury precedes the function change. This study was performed to determine the reference interval for urinary NAG activity (N-Acetyl-β-D-glucosaminidase) in urine of healthy dogs of different breeds, ages and sexes. It was utilized an automated method for the determination of NAG activity standardized for dog urine samples. Through statistical analysis it was observed that NAG is positively correlated with the age of the animal and urine specific gravity but is not interfered by sex or weight. Based on the determination of urinary activity and after correcting the values for a 1,025 urine specific gravity was obtained an reference interval of X ‘= 3.62U/L±0.66U/L. |
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Determination of the reference interval for the activity of N-Acetyl-β-D-Glucosaminidase (NAG) in urine of healthy dogsReference intervalNAcetyl-β-D-glucosaminidaseNAGurinedogsenzimuryinjuryABSTRACT: The diagnosis of acute kidney injury by evaluating the activity of urinary enzymes is an important tool especially for its precocity in relation to methods of assessment of renal function considered late as the installation of injury precedes the function change. This study was performed to determine the reference interval for urinary NAG activity (N-Acetyl-β-D-glucosaminidase) in urine of healthy dogs of different breeds, ages and sexes. It was utilized an automated method for the determination of NAG activity standardized for dog urine samples. Through statistical analysis it was observed that NAG is positively correlated with the age of the animal and urine specific gravity but is not interfered by sex or weight. Based on the determination of urinary activity and after correcting the values for a 1,025 urine specific gravity was obtained an reference interval of X ‘= 3.62U/L±0.66U/L.Colégio Brasileiro de Patologia Animal - CBPA2018-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2018000801685Pesquisa Veterinária Brasileira v.38 n.8 2018reponame:Pesquisa Veterinária Brasileira (Online)instname:Colégio Brasileiro de Patologia Animal (CBPA)instacron:EMBRAPA10.1590/1678-5150-pvb-5025info:eu-repo/semantics/openAccessTassini,Luiz Eduardo S.Leme,Fabiola O.P.Veado,Júlio César C.Arndt,Márcio H.L.eng2018-10-29T00:00:00Zoai:scielo:S0100-736X2018000801685Revistahttp://www.pvb.com.br/https://old.scielo.br/oai/scielo-oai.phpcolegio@cbpa.org.br||pvb@pvb.com.br0100-736X1678-5150opendoar:2018-10-29T00:00Pesquisa Veterinária Brasileira (Online) - Colégio Brasileiro de Patologia Animal (CBPA)false |
| dc.title.none.fl_str_mv |
Determination of the reference interval for the activity of N-Acetyl-β-D-Glucosaminidase (NAG) in urine of healthy dogs |
| title |
Determination of the reference interval for the activity of N-Acetyl-β-D-Glucosaminidase (NAG) in urine of healthy dogs |
| spellingShingle |
Determination of the reference interval for the activity of N-Acetyl-β-D-Glucosaminidase (NAG) in urine of healthy dogs Tassini,Luiz Eduardo S. Reference interval NAcetyl-β-D-glucosaminidase NAG urine dogs enzimury injury |
| title_short |
Determination of the reference interval for the activity of N-Acetyl-β-D-Glucosaminidase (NAG) in urine of healthy dogs |
| title_full |
Determination of the reference interval for the activity of N-Acetyl-β-D-Glucosaminidase (NAG) in urine of healthy dogs |
| title_fullStr |
Determination of the reference interval for the activity of N-Acetyl-β-D-Glucosaminidase (NAG) in urine of healthy dogs |
| title_full_unstemmed |
Determination of the reference interval for the activity of N-Acetyl-β-D-Glucosaminidase (NAG) in urine of healthy dogs |
| title_sort |
Determination of the reference interval for the activity of N-Acetyl-β-D-Glucosaminidase (NAG) in urine of healthy dogs |
| author |
Tassini,Luiz Eduardo S. |
| author_facet |
Tassini,Luiz Eduardo S. Leme,Fabiola O.P. Veado,Júlio César C. Arndt,Márcio H.L. |
| author_role |
author |
| author2 |
Leme,Fabiola O.P. Veado,Júlio César C. Arndt,Márcio H.L. |
| author2_role |
author author author |
| dc.contributor.author.fl_str_mv |
Tassini,Luiz Eduardo S. Leme,Fabiola O.P. Veado,Júlio César C. Arndt,Márcio H.L. |
| dc.subject.por.fl_str_mv |
Reference interval NAcetyl-β-D-glucosaminidase NAG urine dogs enzimury injury |
| topic |
Reference interval NAcetyl-β-D-glucosaminidase NAG urine dogs enzimury injury |
| description |
ABSTRACT: The diagnosis of acute kidney injury by evaluating the activity of urinary enzymes is an important tool especially for its precocity in relation to methods of assessment of renal function considered late as the installation of injury precedes the function change. This study was performed to determine the reference interval for urinary NAG activity (N-Acetyl-β-D-glucosaminidase) in urine of healthy dogs of different breeds, ages and sexes. It was utilized an automated method for the determination of NAG activity standardized for dog urine samples. Through statistical analysis it was observed that NAG is positively correlated with the age of the animal and urine specific gravity but is not interfered by sex or weight. Based on the determination of urinary activity and after correcting the values for a 1,025 urine specific gravity was obtained an reference interval of X ‘= 3.62U/L±0.66U/L. |
| publishDate |
2018 |
| dc.date.none.fl_str_mv |
2018-08-01 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2018000801685 |
| url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2018000801685 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
10.1590/1678-5150-pvb-5025 |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
text/html |
| dc.publisher.none.fl_str_mv |
Colégio Brasileiro de Patologia Animal - CBPA |
| publisher.none.fl_str_mv |
Colégio Brasileiro de Patologia Animal - CBPA |
| dc.source.none.fl_str_mv |
Pesquisa Veterinária Brasileira v.38 n.8 2018 reponame:Pesquisa Veterinária Brasileira (Online) instname:Colégio Brasileiro de Patologia Animal (CBPA) instacron:EMBRAPA |
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Colégio Brasileiro de Patologia Animal (CBPA) |
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EMBRAPA |
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EMBRAPA |
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Pesquisa Veterinária Brasileira (Online) |
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Pesquisa Veterinária Brasileira (Online) |
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Pesquisa Veterinária Brasileira (Online) - Colégio Brasileiro de Patologia Animal (CBPA) |
| repository.mail.fl_str_mv |
colegio@cbpa.org.br||pvb@pvb.com.br |
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1754122238926258176 |