Cardiorespiratory evaluation of brachycephalic syndrome in dogs
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Pesquisa Veterinária Brasileira (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2018000601130 |
Resumo: | ABSTRACT: Brachycephalic syndrome (BS) in dogs is characterized by the combination of primary and secondary upper respiratory tract abnormalities and may result in significant upper airway obstruction. It can trigger inspiratory dyspnea, culminating in secondary respiratory distress, soft tissue edema, upper airway obstruction, turbulent airflow, inspiratory noise, and even death. These changes lead to increased resistance of the air passages, which can cause elevation of pulmonary pressure and clinical manifestations attributable to pulmonary hypertension. The consequence is right-sided cardiac remodeling (Cor pulmonale) with possible progression to right congestive heart failure. To investigate the effects of BS on the cardiovascular system, 28 animals were recruited for a prospective study and assigned to either the Brachycephalic Group (BG), composed of 22 French bulldogs with BS or the Control Group (CG), which was composed of 6 healthy Beagle dogs. All animals underwent a detailed physical examination, as well as laboratory analyses, electrocardiography, echocardiography, chest radiography and indirect measurement of systemic arterial blood pressure. The most relevant finding was a lower PaO2 (90.6±12.9mmHg) in BG as compared to CG (104.9±5.2), (p≤0.05), possibly attributable to hypoventilation due to anatomical alterations. |
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Cardiorespiratory evaluation of brachycephalic syndrome in dogsCardiorespiratory evaluationbrachycephalic syndromedogsCor pulmonalepulmonary hypertensionheart failureFrench BulldoghypoxemiaclinicsABSTRACT: Brachycephalic syndrome (BS) in dogs is characterized by the combination of primary and secondary upper respiratory tract abnormalities and may result in significant upper airway obstruction. It can trigger inspiratory dyspnea, culminating in secondary respiratory distress, soft tissue edema, upper airway obstruction, turbulent airflow, inspiratory noise, and even death. These changes lead to increased resistance of the air passages, which can cause elevation of pulmonary pressure and clinical manifestations attributable to pulmonary hypertension. The consequence is right-sided cardiac remodeling (Cor pulmonale) with possible progression to right congestive heart failure. To investigate the effects of BS on the cardiovascular system, 28 animals were recruited for a prospective study and assigned to either the Brachycephalic Group (BG), composed of 22 French bulldogs with BS or the Control Group (CG), which was composed of 6 healthy Beagle dogs. All animals underwent a detailed physical examination, as well as laboratory analyses, electrocardiography, echocardiography, chest radiography and indirect measurement of systemic arterial blood pressure. The most relevant finding was a lower PaO2 (90.6±12.9mmHg) in BG as compared to CG (104.9±5.2), (p≤0.05), possibly attributable to hypoventilation due to anatomical alterations.Colégio Brasileiro de Patologia Animal - CBPA2018-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2018000601130Pesquisa Veterinária Brasileira v.38 n.6 2018reponame:Pesquisa Veterinária Brasileira (Online)instname:Colégio Brasileiro de Patologia Animal (CBPA)instacron:EMBRAPA10.1590/1678-5150-pvb-5376info:eu-repo/semantics/openAccessCanola,Raphaela A.M.Sousa,Marlos G.Braz,Jaislane B.Restan,Wilmer Alejandro Z.Yamada,Diego I.Silva Filho,Jorge C.Camacho,Aparecido A.eng2018-08-24T00:00:00Zoai:scielo:S0100-736X2018000601130Revistahttp://www.pvb.com.br/https://old.scielo.br/oai/scielo-oai.phpcolegio@cbpa.org.br||pvb@pvb.com.br0100-736X1678-5150opendoar:2018-08-24T00:00Pesquisa Veterinária Brasileira (Online) - Colégio Brasileiro de Patologia Animal (CBPA)false |
dc.title.none.fl_str_mv |
Cardiorespiratory evaluation of brachycephalic syndrome in dogs |
title |
Cardiorespiratory evaluation of brachycephalic syndrome in dogs |
spellingShingle |
Cardiorespiratory evaluation of brachycephalic syndrome in dogs Canola,Raphaela A.M. Cardiorespiratory evaluation brachycephalic syndrome dogs Cor pulmonale pulmonary hypertension heart failure French Bulldog hypoxemia clinics |
title_short |
Cardiorespiratory evaluation of brachycephalic syndrome in dogs |
title_full |
Cardiorespiratory evaluation of brachycephalic syndrome in dogs |
title_fullStr |
Cardiorespiratory evaluation of brachycephalic syndrome in dogs |
title_full_unstemmed |
Cardiorespiratory evaluation of brachycephalic syndrome in dogs |
title_sort |
Cardiorespiratory evaluation of brachycephalic syndrome in dogs |
author |
Canola,Raphaela A.M. |
author_facet |
Canola,Raphaela A.M. Sousa,Marlos G. Braz,Jaislane B. Restan,Wilmer Alejandro Z. Yamada,Diego I. Silva Filho,Jorge C. Camacho,Aparecido A. |
author_role |
author |
author2 |
Sousa,Marlos G. Braz,Jaislane B. Restan,Wilmer Alejandro Z. Yamada,Diego I. Silva Filho,Jorge C. Camacho,Aparecido A. |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Canola,Raphaela A.M. Sousa,Marlos G. Braz,Jaislane B. Restan,Wilmer Alejandro Z. Yamada,Diego I. Silva Filho,Jorge C. Camacho,Aparecido A. |
dc.subject.por.fl_str_mv |
Cardiorespiratory evaluation brachycephalic syndrome dogs Cor pulmonale pulmonary hypertension heart failure French Bulldog hypoxemia clinics |
topic |
Cardiorespiratory evaluation brachycephalic syndrome dogs Cor pulmonale pulmonary hypertension heart failure French Bulldog hypoxemia clinics |
description |
ABSTRACT: Brachycephalic syndrome (BS) in dogs is characterized by the combination of primary and secondary upper respiratory tract abnormalities and may result in significant upper airway obstruction. It can trigger inspiratory dyspnea, culminating in secondary respiratory distress, soft tissue edema, upper airway obstruction, turbulent airflow, inspiratory noise, and even death. These changes lead to increased resistance of the air passages, which can cause elevation of pulmonary pressure and clinical manifestations attributable to pulmonary hypertension. The consequence is right-sided cardiac remodeling (Cor pulmonale) with possible progression to right congestive heart failure. To investigate the effects of BS on the cardiovascular system, 28 animals were recruited for a prospective study and assigned to either the Brachycephalic Group (BG), composed of 22 French bulldogs with BS or the Control Group (CG), which was composed of 6 healthy Beagle dogs. All animals underwent a detailed physical examination, as well as laboratory analyses, electrocardiography, echocardiography, chest radiography and indirect measurement of systemic arterial blood pressure. The most relevant finding was a lower PaO2 (90.6±12.9mmHg) in BG as compared to CG (104.9±5.2), (p≤0.05), possibly attributable to hypoventilation due to anatomical alterations. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2018000601130 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2018000601130 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1678-5150-pvb-5376 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Colégio Brasileiro de Patologia Animal - CBPA |
publisher.none.fl_str_mv |
Colégio Brasileiro de Patologia Animal - CBPA |
dc.source.none.fl_str_mv |
Pesquisa Veterinária Brasileira v.38 n.6 2018 reponame:Pesquisa Veterinária Brasileira (Online) instname:Colégio Brasileiro de Patologia Animal (CBPA) instacron:EMBRAPA |
instname_str |
Colégio Brasileiro de Patologia Animal (CBPA) |
instacron_str |
EMBRAPA |
institution |
EMBRAPA |
reponame_str |
Pesquisa Veterinária Brasileira (Online) |
collection |
Pesquisa Veterinária Brasileira (Online) |
repository.name.fl_str_mv |
Pesquisa Veterinária Brasileira (Online) - Colégio Brasileiro de Patologia Animal (CBPA) |
repository.mail.fl_str_mv |
colegio@cbpa.org.br||pvb@pvb.com.br |
_version_ |
1754122238502633472 |