Cardiorespiratory evaluation of brachycephalic syndrome in dogs

Detalhes bibliográficos
Autor(a) principal: Canola,Raphaela A.M.
Data de Publicação: 2018
Outros Autores: Sousa,Marlos G., Braz,Jaislane B., Restan,Wilmer Alejandro Z., Yamada,Diego I., Silva Filho,Jorge C., Camacho,Aparecido A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Pesquisa Veterinária Brasileira (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2018000601130
Resumo: ABSTRACT: Brachycephalic syndrome (BS) in dogs is characterized by the combination of primary and secondary upper respiratory tract abnormalities and may result in significant upper airway obstruction. It can trigger inspiratory dyspnea, culminating in secondary respiratory distress, soft tissue edema, upper airway obstruction, turbulent airflow, inspiratory noise, and even death. These changes lead to increased resistance of the air passages, which can cause elevation of pulmonary pressure and clinical manifestations attributable to pulmonary hypertension. The consequence is right-sided cardiac remodeling (Cor pulmonale) with possible progression to right congestive heart failure. To investigate the effects of BS on the cardiovascular system, 28 animals were recruited for a prospective study and assigned to either the Brachycephalic Group (BG), composed of 22 French bulldogs with BS or the Control Group (CG), which was composed of 6 healthy Beagle dogs. All animals underwent a detailed physical examination, as well as laboratory analyses, electrocardiography, echocardiography, chest radiography and indirect measurement of systemic arterial blood pressure. The most relevant finding was a lower PaO2 (90.6±12.9mmHg) in BG as compared to CG (104.9±5.2), (p≤0.05), possibly attributable to hypoventilation due to anatomical alterations.
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spelling Cardiorespiratory evaluation of brachycephalic syndrome in dogsCardiorespiratory evaluationbrachycephalic syndromedogsCor pulmonalepulmonary hypertensionheart failureFrench BulldoghypoxemiaclinicsABSTRACT: Brachycephalic syndrome (BS) in dogs is characterized by the combination of primary and secondary upper respiratory tract abnormalities and may result in significant upper airway obstruction. It can trigger inspiratory dyspnea, culminating in secondary respiratory distress, soft tissue edema, upper airway obstruction, turbulent airflow, inspiratory noise, and even death. These changes lead to increased resistance of the air passages, which can cause elevation of pulmonary pressure and clinical manifestations attributable to pulmonary hypertension. The consequence is right-sided cardiac remodeling (Cor pulmonale) with possible progression to right congestive heart failure. To investigate the effects of BS on the cardiovascular system, 28 animals were recruited for a prospective study and assigned to either the Brachycephalic Group (BG), composed of 22 French bulldogs with BS or the Control Group (CG), which was composed of 6 healthy Beagle dogs. All animals underwent a detailed physical examination, as well as laboratory analyses, electrocardiography, echocardiography, chest radiography and indirect measurement of systemic arterial blood pressure. The most relevant finding was a lower PaO2 (90.6±12.9mmHg) in BG as compared to CG (104.9±5.2), (p≤0.05), possibly attributable to hypoventilation due to anatomical alterations.Colégio Brasileiro de Patologia Animal - CBPA2018-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2018000601130Pesquisa Veterinária Brasileira v.38 n.6 2018reponame:Pesquisa Veterinária Brasileira (Online)instname:Colégio Brasileiro de Patologia Animal (CBPA)instacron:EMBRAPA10.1590/1678-5150-pvb-5376info:eu-repo/semantics/openAccessCanola,Raphaela A.M.Sousa,Marlos G.Braz,Jaislane B.Restan,Wilmer Alejandro Z.Yamada,Diego I.Silva Filho,Jorge C.Camacho,Aparecido A.eng2018-08-24T00:00:00Zoai:scielo:S0100-736X2018000601130Revistahttp://www.pvb.com.br/https://old.scielo.br/oai/scielo-oai.phpcolegio@cbpa.org.br||pvb@pvb.com.br0100-736X1678-5150opendoar:2018-08-24T00:00Pesquisa Veterinária Brasileira (Online) - Colégio Brasileiro de Patologia Animal (CBPA)false
dc.title.none.fl_str_mv Cardiorespiratory evaluation of brachycephalic syndrome in dogs
title Cardiorespiratory evaluation of brachycephalic syndrome in dogs
spellingShingle Cardiorespiratory evaluation of brachycephalic syndrome in dogs
Canola,Raphaela A.M.
Cardiorespiratory evaluation
brachycephalic syndrome
dogs
Cor pulmonale
pulmonary hypertension
heart failure
French Bulldog
hypoxemia
clinics
title_short Cardiorespiratory evaluation of brachycephalic syndrome in dogs
title_full Cardiorespiratory evaluation of brachycephalic syndrome in dogs
title_fullStr Cardiorespiratory evaluation of brachycephalic syndrome in dogs
title_full_unstemmed Cardiorespiratory evaluation of brachycephalic syndrome in dogs
title_sort Cardiorespiratory evaluation of brachycephalic syndrome in dogs
author Canola,Raphaela A.M.
author_facet Canola,Raphaela A.M.
Sousa,Marlos G.
Braz,Jaislane B.
Restan,Wilmer Alejandro Z.
Yamada,Diego I.
Silva Filho,Jorge C.
Camacho,Aparecido A.
author_role author
author2 Sousa,Marlos G.
Braz,Jaislane B.
Restan,Wilmer Alejandro Z.
Yamada,Diego I.
Silva Filho,Jorge C.
Camacho,Aparecido A.
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Canola,Raphaela A.M.
Sousa,Marlos G.
Braz,Jaislane B.
Restan,Wilmer Alejandro Z.
Yamada,Diego I.
Silva Filho,Jorge C.
Camacho,Aparecido A.
dc.subject.por.fl_str_mv Cardiorespiratory evaluation
brachycephalic syndrome
dogs
Cor pulmonale
pulmonary hypertension
heart failure
French Bulldog
hypoxemia
clinics
topic Cardiorespiratory evaluation
brachycephalic syndrome
dogs
Cor pulmonale
pulmonary hypertension
heart failure
French Bulldog
hypoxemia
clinics
description ABSTRACT: Brachycephalic syndrome (BS) in dogs is characterized by the combination of primary and secondary upper respiratory tract abnormalities and may result in significant upper airway obstruction. It can trigger inspiratory dyspnea, culminating in secondary respiratory distress, soft tissue edema, upper airway obstruction, turbulent airflow, inspiratory noise, and even death. These changes lead to increased resistance of the air passages, which can cause elevation of pulmonary pressure and clinical manifestations attributable to pulmonary hypertension. The consequence is right-sided cardiac remodeling (Cor pulmonale) with possible progression to right congestive heart failure. To investigate the effects of BS on the cardiovascular system, 28 animals were recruited for a prospective study and assigned to either the Brachycephalic Group (BG), composed of 22 French bulldogs with BS or the Control Group (CG), which was composed of 6 healthy Beagle dogs. All animals underwent a detailed physical examination, as well as laboratory analyses, electrocardiography, echocardiography, chest radiography and indirect measurement of systemic arterial blood pressure. The most relevant finding was a lower PaO2 (90.6±12.9mmHg) in BG as compared to CG (104.9±5.2), (p≤0.05), possibly attributable to hypoventilation due to anatomical alterations.
publishDate 2018
dc.date.none.fl_str_mv 2018-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2018000601130
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2018000601130
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1678-5150-pvb-5376
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Colégio Brasileiro de Patologia Animal - CBPA
publisher.none.fl_str_mv Colégio Brasileiro de Patologia Animal - CBPA
dc.source.none.fl_str_mv Pesquisa Veterinária Brasileira v.38 n.6 2018
reponame:Pesquisa Veterinária Brasileira (Online)
instname:Colégio Brasileiro de Patologia Animal (CBPA)
instacron:EMBRAPA
instname_str Colégio Brasileiro de Patologia Animal (CBPA)
instacron_str EMBRAPA
institution EMBRAPA
reponame_str Pesquisa Veterinária Brasileira (Online)
collection Pesquisa Veterinária Brasileira (Online)
repository.name.fl_str_mv Pesquisa Veterinária Brasileira (Online) - Colégio Brasileiro de Patologia Animal (CBPA)
repository.mail.fl_str_mv colegio@cbpa.org.br||pvb@pvb.com.br
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