Doramectin intoxication in malnourished 15-month-old cattle

Detalhes bibliográficos
Autor(a) principal: Machado,Mizael
Data de Publicação: 2022
Outros Autores: Riet-Correa,Franklin, Pedroso,Pedro M.O., Macêdo,Juliana T.S.A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Pesquisa Veterinária Brasileira (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2022000100229
Resumo: ABSTRACT: Macrocyclic lactones are widely used as endectocides in farm animals. Intoxications occur in situations of overdose and/or malnutrition, in young animals, and in genetically sensitive breeds. We describe the intoxication by doramectin in malnourished 15-month-old cattle that received 1.6 times the recommended dose. The animals presented salivation, ataxia, motor incoordination, reluctance to move, and sternal recumbency. Two animals recovered spontaneously; one died and was necropsied. No gross or microscopic changes were observed. This study suggests that doramectin may cause intoxication when administered to malnourished cattle in doses higher than those recommended and that knowing the history is essential to establish a diagnosis.
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spelling Doramectin intoxication in malnourished 15-month-old cattleCattledoramectinneurological signstoxicityABSTRACT: Macrocyclic lactones are widely used as endectocides in farm animals. Intoxications occur in situations of overdose and/or malnutrition, in young animals, and in genetically sensitive breeds. We describe the intoxication by doramectin in malnourished 15-month-old cattle that received 1.6 times the recommended dose. The animals presented salivation, ataxia, motor incoordination, reluctance to move, and sternal recumbency. Two animals recovered spontaneously; one died and was necropsied. No gross or microscopic changes were observed. This study suggests that doramectin may cause intoxication when administered to malnourished cattle in doses higher than those recommended and that knowing the history is essential to establish a diagnosis.Colégio Brasileiro de Patologia Animal - CBPA2022-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2022000100229Pesquisa Veterinária Brasileira v.42 2022reponame:Pesquisa Veterinária Brasileira (Online)instname:Colégio Brasileiro de Patologia Animal (CBPA)instacron:EMBRAPA10.1590/1678-5150-pvb-7102info:eu-repo/semantics/openAccessMachado,MizaelRiet-Correa,FranklinPedroso,Pedro M.O.Macêdo,Juliana T.S.A.eng2022-07-22T00:00:00Zoai:scielo:S0100-736X2022000100229Revistahttp://www.pvb.com.br/https://old.scielo.br/oai/scielo-oai.phpcolegio@cbpa.org.br||pvb@pvb.com.br0100-736X1678-5150opendoar:2022-07-22T00:00Pesquisa Veterinária Brasileira (Online) - Colégio Brasileiro de Patologia Animal (CBPA)false
dc.title.none.fl_str_mv Doramectin intoxication in malnourished 15-month-old cattle
title Doramectin intoxication in malnourished 15-month-old cattle
spellingShingle Doramectin intoxication in malnourished 15-month-old cattle
Machado,Mizael
Cattle
doramectin
neurological signs
toxicity
title_short Doramectin intoxication in malnourished 15-month-old cattle
title_full Doramectin intoxication in malnourished 15-month-old cattle
title_fullStr Doramectin intoxication in malnourished 15-month-old cattle
title_full_unstemmed Doramectin intoxication in malnourished 15-month-old cattle
title_sort Doramectin intoxication in malnourished 15-month-old cattle
author Machado,Mizael
author_facet Machado,Mizael
Riet-Correa,Franklin
Pedroso,Pedro M.O.
Macêdo,Juliana T.S.A.
author_role author
author2 Riet-Correa,Franklin
Pedroso,Pedro M.O.
Macêdo,Juliana T.S.A.
author2_role author
author
author
dc.contributor.author.fl_str_mv Machado,Mizael
Riet-Correa,Franklin
Pedroso,Pedro M.O.
Macêdo,Juliana T.S.A.
dc.subject.por.fl_str_mv Cattle
doramectin
neurological signs
toxicity
topic Cattle
doramectin
neurological signs
toxicity
description ABSTRACT: Macrocyclic lactones are widely used as endectocides in farm animals. Intoxications occur in situations of overdose and/or malnutrition, in young animals, and in genetically sensitive breeds. We describe the intoxication by doramectin in malnourished 15-month-old cattle that received 1.6 times the recommended dose. The animals presented salivation, ataxia, motor incoordination, reluctance to move, and sternal recumbency. Two animals recovered spontaneously; one died and was necropsied. No gross or microscopic changes were observed. This study suggests that doramectin may cause intoxication when administered to malnourished cattle in doses higher than those recommended and that knowing the history is essential to establish a diagnosis.
publishDate 2022
dc.date.none.fl_str_mv 2022-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2022000100229
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2022000100229
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1678-5150-pvb-7102
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Colégio Brasileiro de Patologia Animal - CBPA
publisher.none.fl_str_mv Colégio Brasileiro de Patologia Animal - CBPA
dc.source.none.fl_str_mv Pesquisa Veterinária Brasileira v.42 2022
reponame:Pesquisa Veterinária Brasileira (Online)
instname:Colégio Brasileiro de Patologia Animal (CBPA)
instacron:EMBRAPA
instname_str Colégio Brasileiro de Patologia Animal (CBPA)
instacron_str EMBRAPA
institution EMBRAPA
reponame_str Pesquisa Veterinária Brasileira (Online)
collection Pesquisa Veterinária Brasileira (Online)
repository.name.fl_str_mv Pesquisa Veterinária Brasileira (Online) - Colégio Brasileiro de Patologia Animal (CBPA)
repository.mail.fl_str_mv colegio@cbpa.org.br||pvb@pvb.com.br
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