Histopathological alterations in liver of Nile tilapia supplemented with selenomethionine

Detalhes bibliográficos
Autor(a) principal: Gomes, Gabriela Roncada
Data de Publicação: 2016
Outros Autores: Cruz, Claudinei da, Sakabe, Róberson, Ramos, Fabrício Menezes, Fujimoto, Rodrigo Yudi
Tipo de documento: Artigo
Idioma: por
Título da fonte: Pesquisa Agropecuária Brasileira (Online)
Texto Completo: https://seer.sct.embrapa.br/index.php/pab/article/view/22277
Resumo: The objective of this work was to evaluate the effects of selenomethionine supplementation on liver histopathology of Nile tilapia (Oreochromis niloticus). Selenomethionine was added to the base diet (without supplementation) at the concentrations of 0.25, 0.50, 1.0, and 1.50 mg kg-1, which consisted of five treatments, with four replicates. After 90 days of experiment, hepatic lipid degeneration was observed in the liver of the animals that received diet without supplementation, indicating selenium deficiency. However, the animals that received above 1.0 mg kg-1 showed hypertrophy, glycogen accumulation, cordonal disarrangement, foci of necrosis and lipid peroxidation in the liver. Selenium is essential for Nile tilapia nutrition; however, concentrations above 1.0 mg kg-1 selenomethionine impair the liver metabolism.
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spelling Histopathological alterations in liver of Nile tilapia supplemented with selenomethionineHistopatologia do fígado de tilápias‑do‑nilo suplementadas com selenometioninaOreochromis niloticus; hepatocytes; micronutrients; toxicityOreochromis niloticus; hepatócitos; micronutrientes; toxicidadeThe objective of this work was to evaluate the effects of selenomethionine supplementation on liver histopathology of Nile tilapia (Oreochromis niloticus). Selenomethionine was added to the base diet (without supplementation) at the concentrations of 0.25, 0.50, 1.0, and 1.50 mg kg-1, which consisted of five treatments, with four replicates. After 90 days of experiment, hepatic lipid degeneration was observed in the liver of the animals that received diet without supplementation, indicating selenium deficiency. However, the animals that received above 1.0 mg kg-1 showed hypertrophy, glycogen accumulation, cordonal disarrangement, foci of necrosis and lipid peroxidation in the liver. Selenium is essential for Nile tilapia nutrition; however, concentrations above 1.0 mg kg-1 selenomethionine impair the liver metabolism.O objetivo deste trabalho foi avaliar o efeito dietário da selenometionina sobre a histopatologia do fígado de tilápia‑do‑nilo (Oreochromis niloticus). A selenometionina foi adicionada à dieta‑base (sem suplementação) nas doses de 0,25, 0,50, 1,0 e 1,50 mg kg-1, que consistiram em cinco tratamentos, com quatro repetições. Após 90 dias de experimento, foi observada degeneração lipídica no fígado dos animais que receberam a dieta sem suplementação, o que indica deficiência de selênio. No entanto, os animais que receberam acima de 1,0 mg kg-1 apresentaram hipertrofia, acúmulo de glicogênio, desarranjo cordonal, focos de necrose e degeneração lipídica no fígado. A incorporação de selênio é essencial para a nutrição de tilápias‑do‑nilo; porém, níveis acima de 1,0 mg kg-1 de selenometionina prejudicam o metabolismo hepático.Pesquisa Agropecuaria BrasileiraPesquisa Agropecuária BrasileiraConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Gomes, Gabriela RoncadaCruz, Claudinei daSakabe, RóbersonRamos, Fabrício MenezesFujimoto, Rodrigo Yudi2016-05-19info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://seer.sct.embrapa.br/index.php/pab/article/view/22277Pesquisa Agropecuaria Brasileira; v.51, n.3, mar. 2016; 288-291Pesquisa Agropecuária Brasileira; v.51, n.3, mar. 2016; 288-2911678-39210100-104xreponame:Pesquisa Agropecuária Brasileira (Online)instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)instacron:EMBRAPAporhttps://seer.sct.embrapa.br/index.php/pab/article/view/22277/13285https://seer.sct.embrapa.br/index.php/pab/article/downloadSuppFile/22277/14295Direitos autorais 2016 Pesquisa Agropecuária Brasileirainfo:eu-repo/semantics/openAccess2016-05-19T18:03:31Zoai:ojs.seer.sct.embrapa.br:article/22277Revistahttp://seer.sct.embrapa.br/index.php/pabPRIhttps://old.scielo.br/oai/scielo-oai.phppab@sct.embrapa.br || sct.pab@embrapa.br1678-39210100-204Xopendoar:2016-05-19T18:03:31Pesquisa Agropecuária Brasileira (Online) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa)false
dc.title.none.fl_str_mv Histopathological alterations in liver of Nile tilapia supplemented with selenomethionine
Histopatologia do fígado de tilápias‑do‑nilo suplementadas com selenometionina
title Histopathological alterations in liver of Nile tilapia supplemented with selenomethionine
spellingShingle Histopathological alterations in liver of Nile tilapia supplemented with selenomethionine
Gomes, Gabriela Roncada
Oreochromis niloticus; hepatocytes; micronutrients; toxicity
Oreochromis niloticus; hepatócitos; micronutrientes; toxicidade
title_short Histopathological alterations in liver of Nile tilapia supplemented with selenomethionine
title_full Histopathological alterations in liver of Nile tilapia supplemented with selenomethionine
title_fullStr Histopathological alterations in liver of Nile tilapia supplemented with selenomethionine
title_full_unstemmed Histopathological alterations in liver of Nile tilapia supplemented with selenomethionine
title_sort Histopathological alterations in liver of Nile tilapia supplemented with selenomethionine
author Gomes, Gabriela Roncada
author_facet Gomes, Gabriela Roncada
Cruz, Claudinei da
Sakabe, Róberson
Ramos, Fabrício Menezes
Fujimoto, Rodrigo Yudi
author_role author
author2 Cruz, Claudinei da
Sakabe, Róberson
Ramos, Fabrício Menezes
Fujimoto, Rodrigo Yudi
author2_role author
author
author
author
dc.contributor.none.fl_str_mv
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.contributor.author.fl_str_mv Gomes, Gabriela Roncada
Cruz, Claudinei da
Sakabe, Róberson
Ramos, Fabrício Menezes
Fujimoto, Rodrigo Yudi
dc.subject.por.fl_str_mv Oreochromis niloticus; hepatocytes; micronutrients; toxicity
Oreochromis niloticus; hepatócitos; micronutrientes; toxicidade
topic Oreochromis niloticus; hepatocytes; micronutrients; toxicity
Oreochromis niloticus; hepatócitos; micronutrientes; toxicidade
description The objective of this work was to evaluate the effects of selenomethionine supplementation on liver histopathology of Nile tilapia (Oreochromis niloticus). Selenomethionine was added to the base diet (without supplementation) at the concentrations of 0.25, 0.50, 1.0, and 1.50 mg kg-1, which consisted of five treatments, with four replicates. After 90 days of experiment, hepatic lipid degeneration was observed in the liver of the animals that received diet without supplementation, indicating selenium deficiency. However, the animals that received above 1.0 mg kg-1 showed hypertrophy, glycogen accumulation, cordonal disarrangement, foci of necrosis and lipid peroxidation in the liver. Selenium is essential for Nile tilapia nutrition; however, concentrations above 1.0 mg kg-1 selenomethionine impair the liver metabolism.
publishDate 2016
dc.date.none.fl_str_mv 2016-05-19
dc.type.none.fl_str_mv
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://seer.sct.embrapa.br/index.php/pab/article/view/22277
url https://seer.sct.embrapa.br/index.php/pab/article/view/22277
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://seer.sct.embrapa.br/index.php/pab/article/view/22277/13285
https://seer.sct.embrapa.br/index.php/pab/article/downloadSuppFile/22277/14295
dc.rights.driver.fl_str_mv Direitos autorais 2016 Pesquisa Agropecuária Brasileira
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Direitos autorais 2016 Pesquisa Agropecuária Brasileira
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Pesquisa Agropecuaria Brasileira
Pesquisa Agropecuária Brasileira
publisher.none.fl_str_mv Pesquisa Agropecuaria Brasileira
Pesquisa Agropecuária Brasileira
dc.source.none.fl_str_mv Pesquisa Agropecuaria Brasileira; v.51, n.3, mar. 2016; 288-291
Pesquisa Agropecuária Brasileira; v.51, n.3, mar. 2016; 288-291
1678-3921
0100-104x
reponame:Pesquisa Agropecuária Brasileira (Online)
instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
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reponame_str Pesquisa Agropecuária Brasileira (Online)
collection Pesquisa Agropecuária Brasileira (Online)
repository.name.fl_str_mv Pesquisa Agropecuária Brasileira (Online) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
repository.mail.fl_str_mv pab@sct.embrapa.br || sct.pab@embrapa.br
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