Vaccinia virus antibodies in calves submitted to experimental infection

Detalhes bibliográficos
Autor(a) principal: Schatzmayr, Hermann G.
Data de Publicação: 2014
Outros Autores: Denne, Yone e Silva
Tipo de documento: Artigo
Idioma: por
Título da fonte: Pesquisa Agropecuária Brasileira (Online)
Texto Completo: https://seer.sct.embrapa.br/index.php/pab/article/view/17213
Resumo: Antibody formation for Vaccinia virus, after inoculation in calves, used for Smallpox vaccine preparation, have been tested. Complement-fixing, hemagglutination inhibition, neutralizing and precipitating antibodies have been demonstrated. The globulin class of these antibodies has also been determined after gel filtration in Sephadex G-200. A fast antibody formation in the animals has been observed like the one observed in human re-vaccination and faster than that observed in the human prime vaccination. The pattern observed on formation and decrease of globulins IgM suggest its use in the diagnosis of recent infections by Pox viruses. This is particularly important in order to make a differential diagnosis with other vesicular virus infections and older infections or vaccinations with members of Pox viruses group.
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spelling Vaccinia virus antibodies in calves submitted to experimental infectionAnticorpos para o vírus Vaccínia na infecção experimental em bovinosPox virusVírus vaccínico; imunoglobulinas; respostas de anticorposAntibody formation for Vaccinia virus, after inoculation in calves, used for Smallpox vaccine preparation, have been tested. Complement-fixing, hemagglutination inhibition, neutralizing and precipitating antibodies have been demonstrated. The globulin class of these antibodies has also been determined after gel filtration in Sephadex G-200. A fast antibody formation in the animals has been observed like the one observed in human re-vaccination and faster than that observed in the human prime vaccination. The pattern observed on formation and decrease of globulins IgM suggest its use in the diagnosis of recent infections by Pox viruses. This is particularly important in order to make a differential diagnosis with other vesicular virus infections and older infections or vaccinations with members of Pox viruses group.Anticorpos para o vírus Vaccínia, formados após inoculação em bovinos usados no preparo de vacina antivariólica, foram testados. Titularam-se os anticorpos inibidores de hemaglutinação, fixadores do complemento, neutralizantes e precipitantes. A classe de globulinas a que pertenciam estes anticorpos foi determinada, através de prévia filtração em gel de Sephadex G-200. Observou-se uma rápida formação de anticorpos nos animais, aparentemente mais rápida do que a resposta em pessoas primo-vacinadas e próxima à resposta em revacinados. O padrão de formação e o desaparecimento precoce das globulinas IgM sugere sua utilidade no diagnóstico de infecções recentes do grupo Pox, o que teria aplicação importante no diagnóstico diferencial de outras infecções vesiculares, bem como na caracterização de anticorpos devidos a antigas vacinações ou infecções por membros deste grupo de vírus.Pesquisa Agropecuaria BrasileiraPesquisa Agropecuária BrasileiraSchatzmayr, Hermann G.Denne, Yone e Silva2014-04-15info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://seer.sct.embrapa.br/index.php/pab/article/view/17213Pesquisa Agropecuaria Brasileira; v.9, n.7, 1974: Série Veterinária; 25-28Pesquisa Agropecuária Brasileira; v.9, n.7, 1974: Série Veterinária; 25-281678-39210100-104xreponame:Pesquisa Agropecuária Brasileira (Online)instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)instacron:EMBRAPAporhttps://seer.sct.embrapa.br/index.php/pab/article/view/17213/11531info:eu-repo/semantics/openAccess2014-04-15T18:57:58Zoai:ojs.seer.sct.embrapa.br:article/17213Revistahttp://seer.sct.embrapa.br/index.php/pabPRIhttps://old.scielo.br/oai/scielo-oai.phppab@sct.embrapa.br || sct.pab@embrapa.br1678-39210100-204Xopendoar:2014-04-15T18:57:58Pesquisa Agropecuária Brasileira (Online) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa)false
dc.title.none.fl_str_mv Vaccinia virus antibodies in calves submitted to experimental infection
Anticorpos para o vírus Vaccínia na infecção experimental em bovinos
title Vaccinia virus antibodies in calves submitted to experimental infection
spellingShingle Vaccinia virus antibodies in calves submitted to experimental infection
Schatzmayr, Hermann G.
Pox virus
Vírus vaccínico; imunoglobulinas; respostas de anticorpos
title_short Vaccinia virus antibodies in calves submitted to experimental infection
title_full Vaccinia virus antibodies in calves submitted to experimental infection
title_fullStr Vaccinia virus antibodies in calves submitted to experimental infection
title_full_unstemmed Vaccinia virus antibodies in calves submitted to experimental infection
title_sort Vaccinia virus antibodies in calves submitted to experimental infection
author Schatzmayr, Hermann G.
author_facet Schatzmayr, Hermann G.
Denne, Yone e Silva
author_role author
author2 Denne, Yone e Silva
author2_role author
dc.contributor.none.fl_str_mv

dc.contributor.author.fl_str_mv Schatzmayr, Hermann G.
Denne, Yone e Silva
dc.subject.por.fl_str_mv Pox virus
Vírus vaccínico; imunoglobulinas; respostas de anticorpos
topic Pox virus
Vírus vaccínico; imunoglobulinas; respostas de anticorpos
description Antibody formation for Vaccinia virus, after inoculation in calves, used for Smallpox vaccine preparation, have been tested. Complement-fixing, hemagglutination inhibition, neutralizing and precipitating antibodies have been demonstrated. The globulin class of these antibodies has also been determined after gel filtration in Sephadex G-200. A fast antibody formation in the animals has been observed like the one observed in human re-vaccination and faster than that observed in the human prime vaccination. The pattern observed on formation and decrease of globulins IgM suggest its use in the diagnosis of recent infections by Pox viruses. This is particularly important in order to make a differential diagnosis with other vesicular virus infections and older infections or vaccinations with members of Pox viruses group.
publishDate 2014
dc.date.none.fl_str_mv 2014-04-15
dc.type.none.fl_str_mv
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://seer.sct.embrapa.br/index.php/pab/article/view/17213
url https://seer.sct.embrapa.br/index.php/pab/article/view/17213
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://seer.sct.embrapa.br/index.php/pab/article/view/17213/11531
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Pesquisa Agropecuaria Brasileira
Pesquisa Agropecuária Brasileira
publisher.none.fl_str_mv Pesquisa Agropecuaria Brasileira
Pesquisa Agropecuária Brasileira
dc.source.none.fl_str_mv Pesquisa Agropecuaria Brasileira; v.9, n.7, 1974: Série Veterinária; 25-28
Pesquisa Agropecuária Brasileira; v.9, n.7, 1974: Série Veterinária; 25-28
1678-3921
0100-104x
reponame:Pesquisa Agropecuária Brasileira (Online)
instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron:EMBRAPA
instname_str Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron_str EMBRAPA
institution EMBRAPA
reponame_str Pesquisa Agropecuária Brasileira (Online)
collection Pesquisa Agropecuária Brasileira (Online)
repository.name.fl_str_mv Pesquisa Agropecuária Brasileira (Online) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
repository.mail.fl_str_mv pab@sct.embrapa.br || sct.pab@embrapa.br
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