Nanocellulose-based porous materials: Regulation and pathway to commercialization in regenerative medicine.
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) |
Texto Completo: | http://www.alice.cnptia.embrapa.br/alice/handle/doc/1155053 https://doi.org/10.1016/j.bioactmat.2023.06.020 |
Resumo: | We review the recent progress that have led to the development of porous materials based on cellulose nanostructures found in plants and other resources. In light of the properties that emerge from the chemistry, shape and structural control, we discuss some of the most promising uses of a plant-based material, nanocellulose, in regenerative medicine. Following a brief discussion about the fundamental aspects of self-assembly of nanocellulose precursors, we review the key strategies needed for material synthesis and to adjust the architecture of the materials (using three-dimensional printing, freeze-casted porous materials, and electrospinning) according to their uses in tissue engineering, artificial organs, controlled drug delivery and wound healing systems, among others. For this purpose, we map the structure?property?function relationships of nanocellulose-based porous materials and examine the course of actions that are required to translate innovation from the laboratory to industry. Such efforts require attention to regulatory aspects and market pull. Finally, the key challenges and opportunities in this nascent field are critically reviewed. |
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Nanocellulose-based porous materials: Regulation and pathway to commercialization in regenerative medicine.Regenerative medicineBiomaterialSustainable materialsGreen nanomaterialsWe review the recent progress that have led to the development of porous materials based on cellulose nanostructures found in plants and other resources. In light of the properties that emerge from the chemistry, shape and structural control, we discuss some of the most promising uses of a plant-based material, nanocellulose, in regenerative medicine. Following a brief discussion about the fundamental aspects of self-assembly of nanocellulose precursors, we review the key strategies needed for material synthesis and to adjust the architecture of the materials (using three-dimensional printing, freeze-casted porous materials, and electrospinning) according to their uses in tissue engineering, artificial organs, controlled drug delivery and wound healing systems, among others. For this purpose, we map the structure?property?function relationships of nanocellulose-based porous materials and examine the course of actions that are required to translate innovation from the laboratory to industry. Such efforts require attention to regulatory aspects and market pull. Finally, the key challenges and opportunities in this nascent field are critically reviewed.LNNA Embrapa Instrumentação; Federal University of ABC, Santo André; Aalto University, Aalto, Espoo, Finland; Aston Institute of Materials Research, Aston University, Birmingham, UK; Technological Institute of Aeronautics (ITA), Sao Jose dos Campos, SP, Brazil; DANIEL SOUZA CORREA, CNPDIA; Empa - Swiss Federal Laboratories for Materials Science and Technology, Überlandstrasse 129, 8600, Dübendorf, S; University of Araraquara (UNIARA), Araraquara; Federal University of ABC (UFABC), Santo André, Brazil; LUIZ HENRIQUE CAPPARELLI MATTOSO, CNPDIA; The University of British Columbia, 2360 East Mall, Vancouver, BC.FERREIRA, F. V.SOUZA, A. G.AJDARY, R.SOUZA, L. P. deLOPES. J. H.CORREA, D. S.SIQUEIRA, G.BARUD, H. S.ROSA, D. S.MATTOSO, L. H. C.ROJAS, O. J.2024-01-16T11:42:21Z2024-01-16T11:42:21Z2023-07-192023info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article151 - 176Bioactive Materials, v. 29, 2023.2452-199Xhttp://www.alice.cnptia.embrapa.br/alice/handle/doc/1155053https://doi.org/10.1016/j.bioactmat.2023.06.020enginfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)instacron:EMBRAPA2024-01-16T11:42:21Zoai:www.alice.cnptia.embrapa.br:doc/1155053Repositório InstitucionalPUBhttps://www.alice.cnptia.embrapa.br/oai/requestopendoar:21542024-01-16T11:42:21falseRepositório InstitucionalPUBhttps://www.alice.cnptia.embrapa.br/oai/requestcg-riaa@embrapa.bropendoar:21542024-01-16T11:42:21Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa)false |
dc.title.none.fl_str_mv |
Nanocellulose-based porous materials: Regulation and pathway to commercialization in regenerative medicine. |
title |
Nanocellulose-based porous materials: Regulation and pathway to commercialization in regenerative medicine. |
spellingShingle |
Nanocellulose-based porous materials: Regulation and pathway to commercialization in regenerative medicine. FERREIRA, F. V. Regenerative medicine Biomaterial Sustainable materials Green nanomaterials |
title_short |
Nanocellulose-based porous materials: Regulation and pathway to commercialization in regenerative medicine. |
title_full |
Nanocellulose-based porous materials: Regulation and pathway to commercialization in regenerative medicine. |
title_fullStr |
Nanocellulose-based porous materials: Regulation and pathway to commercialization in regenerative medicine. |
title_full_unstemmed |
Nanocellulose-based porous materials: Regulation and pathway to commercialization in regenerative medicine. |
title_sort |
Nanocellulose-based porous materials: Regulation and pathway to commercialization in regenerative medicine. |
author |
FERREIRA, F. V. |
author_facet |
FERREIRA, F. V. SOUZA, A. G. AJDARY, R. SOUZA, L. P. de LOPES. J. H. CORREA, D. S. SIQUEIRA, G. BARUD, H. S. ROSA, D. S. MATTOSO, L. H. C. ROJAS, O. J. |
author_role |
author |
author2 |
SOUZA, A. G. AJDARY, R. SOUZA, L. P. de LOPES. J. H. CORREA, D. S. SIQUEIRA, G. BARUD, H. S. ROSA, D. S. MATTOSO, L. H. C. ROJAS, O. J. |
author2_role |
author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
LNNA Embrapa Instrumentação; Federal University of ABC, Santo André; Aalto University, Aalto, Espoo, Finland; Aston Institute of Materials Research, Aston University, Birmingham, UK; Technological Institute of Aeronautics (ITA), Sao Jose dos Campos, SP, Brazil; DANIEL SOUZA CORREA, CNPDIA; Empa - Swiss Federal Laboratories for Materials Science and Technology, Überlandstrasse 129, 8600, Dübendorf, S; University of Araraquara (UNIARA), Araraquara; Federal University of ABC (UFABC), Santo André, Brazil; LUIZ HENRIQUE CAPPARELLI MATTOSO, CNPDIA; The University of British Columbia, 2360 East Mall, Vancouver, BC. |
dc.contributor.author.fl_str_mv |
FERREIRA, F. V. SOUZA, A. G. AJDARY, R. SOUZA, L. P. de LOPES. J. H. CORREA, D. S. SIQUEIRA, G. BARUD, H. S. ROSA, D. S. MATTOSO, L. H. C. ROJAS, O. J. |
dc.subject.por.fl_str_mv |
Regenerative medicine Biomaterial Sustainable materials Green nanomaterials |
topic |
Regenerative medicine Biomaterial Sustainable materials Green nanomaterials |
description |
We review the recent progress that have led to the development of porous materials based on cellulose nanostructures found in plants and other resources. In light of the properties that emerge from the chemistry, shape and structural control, we discuss some of the most promising uses of a plant-based material, nanocellulose, in regenerative medicine. Following a brief discussion about the fundamental aspects of self-assembly of nanocellulose precursors, we review the key strategies needed for material synthesis and to adjust the architecture of the materials (using three-dimensional printing, freeze-casted porous materials, and electrospinning) according to their uses in tissue engineering, artificial organs, controlled drug delivery and wound healing systems, among others. For this purpose, we map the structure?property?function relationships of nanocellulose-based porous materials and examine the course of actions that are required to translate innovation from the laboratory to industry. Such efforts require attention to regulatory aspects and market pull. Finally, the key challenges and opportunities in this nascent field are critically reviewed. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-07-19 2023 2024-01-16T11:42:21Z 2024-01-16T11:42:21Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
Bioactive Materials, v. 29, 2023. 2452-199X http://www.alice.cnptia.embrapa.br/alice/handle/doc/1155053 https://doi.org/10.1016/j.bioactmat.2023.06.020 |
identifier_str_mv |
Bioactive Materials, v. 29, 2023. 2452-199X |
url |
http://www.alice.cnptia.embrapa.br/alice/handle/doc/1155053 https://doi.org/10.1016/j.bioactmat.2023.06.020 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
151 - 176 |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa) instacron:EMBRAPA |
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Empresa Brasileira de Pesquisa Agropecuária (Embrapa) |
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EMBRAPA |
institution |
EMBRAPA |
reponame_str |
Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) |
collection |
Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) |
repository.name.fl_str_mv |
Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa) |
repository.mail.fl_str_mv |
cg-riaa@embrapa.br |
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1794503556024238080 |