Genetic characterization of Indubrasil cattle breed population.

Detalhes bibliográficos
Autor(a) principal: ZANELLA, R.
Data de Publicação: 2018
Outros Autores: LAGO, L. V., SILVA, A. N. da, PÉRTILLE, F., CARVALHO, N. S. de, PANETTO, J. C. do C., ZANELLA, G. C., FACIOLI, F. L., SILVA, M. V. G. B.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
Texto Completo: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1101944
Resumo: Abstract The Indubrasil breed was developed in the Brazilian region called Triângulo Mineiro as a result of a cross between zebu cattle. Initially, it was used as a terminal cross and currently it represents approximately 4.45% of all the Brazilian zebu cattle. Studies were conducted to estimate genetic parameters in the Indubrasil using pedigree information, however, until now, no study has been developed using large-scale genomic markers in this breed. Pedigree information are widely used to investigate population parameters; however, they can neglect some estimates when compared to the use of genomic markers. Therefore, the objective of this study was to investigate the population structure and the genetic diversity of Indubrasil cattle using a high-density Single Nucleotide Polymorphism (SNP) panel (Illumina BovineHD BeadChip 700k). Levels of genomic homozygosity were evaluated using three different approaches: Runs of homozygosity (FROH), % of homozygosis (FSNP), and inbreeding coefficient (Fx). Further, Runs of Homozygosity (ROH) segments conserved among the animals were investigated to identify possible regions associated with the breed characteristics. Our results indicate that even the Indubrasil breed having a small effective population size, the levels of homozygosity (FROH = 0.046) are still small. This was possibly caused by the cross conducted among different breeds for its development. It suggests no immediate risks associated with loss of genetic variation. This information might be used in breeding programs, for the breed conservation and for the expansion of the Indubrasil breed.
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spelling Genetic characterization of Indubrasil cattle breed population.IndubrasilSNPsGenetic diversityInbreedingPedigreeAbstract The Indubrasil breed was developed in the Brazilian region called Triângulo Mineiro as a result of a cross between zebu cattle. Initially, it was used as a terminal cross and currently it represents approximately 4.45% of all the Brazilian zebu cattle. Studies were conducted to estimate genetic parameters in the Indubrasil using pedigree information, however, until now, no study has been developed using large-scale genomic markers in this breed. Pedigree information are widely used to investigate population parameters; however, they can neglect some estimates when compared to the use of genomic markers. Therefore, the objective of this study was to investigate the population structure and the genetic diversity of Indubrasil cattle using a high-density Single Nucleotide Polymorphism (SNP) panel (Illumina BovineHD BeadChip 700k). Levels of genomic homozygosity were evaluated using three different approaches: Runs of homozygosity (FROH), % of homozygosis (FSNP), and inbreeding coefficient (Fx). Further, Runs of Homozygosity (ROH) segments conserved among the animals were investigated to identify possible regions associated with the breed characteristics. Our results indicate that even the Indubrasil breed having a small effective population size, the levels of homozygosity (FROH = 0.046) are still small. This was possibly caused by the cross conducted among different breeds for its development. It suggests no immediate risks associated with loss of genetic variation. This information might be used in breeding programs, for the breed conservation and for the expansion of the Indubrasil breed.RICARDO ZANELLA, Universidade de Passo Fundo; LUÍSA V. LAGO, Universidade de Passo Fundo; ARTHUR N. DA SILVA, Universidade de Passo Fundo; FÁBIO PÉRTILLE, ESALQ/USP; NATHÃ S. de CARVALHO, UFRGS; JOAO CLAUDIO DO CARMO PANETTO, CNPGL; GIOVANA C. ZANELLA, Universidade de Passo Fundo; FERNANDA L. FACIOLI, Universidade de Passo Fundo; MARCOS VINICIUS GUALBERTO B SILVA, CNPGL.ZANELLA, R.LAGO, L. V.SILVA, A. N. daPÉRTILLE, F.CARVALHO, N. S. dePANETTO, J. C. do C.ZANELLA, G. C.FACIOLI, F. L.SILVA, M. V. G. B.2018-12-20T23:41:12Z2018-12-20T23:41:12Z2018-12-1820182018-12-20T23:41:12Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10 p.Veterinary Sciences, v. 5, n. 4, 2018.http://www.alice.cnptia.embrapa.br/alice/handle/doc/110194410.3390/vetsci5040098enginfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)instacron:EMBRAPA2018-12-20T23:41:18Zoai:www.alice.cnptia.embrapa.br:doc/1101944Repositório InstitucionalPUBhttps://www.alice.cnptia.embrapa.br/oai/requestopendoar:21542018-12-20T23:41:18falseRepositório InstitucionalPUBhttps://www.alice.cnptia.embrapa.br/oai/requestcg-riaa@embrapa.bropendoar:21542018-12-20T23:41:18Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa)false
dc.title.none.fl_str_mv Genetic characterization of Indubrasil cattle breed population.
title Genetic characterization of Indubrasil cattle breed population.
spellingShingle Genetic characterization of Indubrasil cattle breed population.
ZANELLA, R.
Indubrasil
SNPs
Genetic diversity
Inbreeding
Pedigree
title_short Genetic characterization of Indubrasil cattle breed population.
title_full Genetic characterization of Indubrasil cattle breed population.
title_fullStr Genetic characterization of Indubrasil cattle breed population.
title_full_unstemmed Genetic characterization of Indubrasil cattle breed population.
title_sort Genetic characterization of Indubrasil cattle breed population.
author ZANELLA, R.
author_facet ZANELLA, R.
LAGO, L. V.
SILVA, A. N. da
PÉRTILLE, F.
CARVALHO, N. S. de
PANETTO, J. C. do C.
ZANELLA, G. C.
FACIOLI, F. L.
SILVA, M. V. G. B.
author_role author
author2 LAGO, L. V.
SILVA, A. N. da
PÉRTILLE, F.
CARVALHO, N. S. de
PANETTO, J. C. do C.
ZANELLA, G. C.
FACIOLI, F. L.
SILVA, M. V. G. B.
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv RICARDO ZANELLA, Universidade de Passo Fundo; LUÍSA V. LAGO, Universidade de Passo Fundo; ARTHUR N. DA SILVA, Universidade de Passo Fundo; FÁBIO PÉRTILLE, ESALQ/USP; NATHÃ S. de CARVALHO, UFRGS; JOAO CLAUDIO DO CARMO PANETTO, CNPGL; GIOVANA C. ZANELLA, Universidade de Passo Fundo; FERNANDA L. FACIOLI, Universidade de Passo Fundo; MARCOS VINICIUS GUALBERTO B SILVA, CNPGL.
dc.contributor.author.fl_str_mv ZANELLA, R.
LAGO, L. V.
SILVA, A. N. da
PÉRTILLE, F.
CARVALHO, N. S. de
PANETTO, J. C. do C.
ZANELLA, G. C.
FACIOLI, F. L.
SILVA, M. V. G. B.
dc.subject.por.fl_str_mv Indubrasil
SNPs
Genetic diversity
Inbreeding
Pedigree
topic Indubrasil
SNPs
Genetic diversity
Inbreeding
Pedigree
description Abstract The Indubrasil breed was developed in the Brazilian region called Triângulo Mineiro as a result of a cross between zebu cattle. Initially, it was used as a terminal cross and currently it represents approximately 4.45% of all the Brazilian zebu cattle. Studies were conducted to estimate genetic parameters in the Indubrasil using pedigree information, however, until now, no study has been developed using large-scale genomic markers in this breed. Pedigree information are widely used to investigate population parameters; however, they can neglect some estimates when compared to the use of genomic markers. Therefore, the objective of this study was to investigate the population structure and the genetic diversity of Indubrasil cattle using a high-density Single Nucleotide Polymorphism (SNP) panel (Illumina BovineHD BeadChip 700k). Levels of genomic homozygosity were evaluated using three different approaches: Runs of homozygosity (FROH), % of homozygosis (FSNP), and inbreeding coefficient (Fx). Further, Runs of Homozygosity (ROH) segments conserved among the animals were investigated to identify possible regions associated with the breed characteristics. Our results indicate that even the Indubrasil breed having a small effective population size, the levels of homozygosity (FROH = 0.046) are still small. This was possibly caused by the cross conducted among different breeds for its development. It suggests no immediate risks associated with loss of genetic variation. This information might be used in breeding programs, for the breed conservation and for the expansion of the Indubrasil breed.
publishDate 2018
dc.date.none.fl_str_mv 2018-12-20T23:41:12Z
2018-12-20T23:41:12Z
2018-12-18
2018
2018-12-20T23:41:12Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv Veterinary Sciences, v. 5, n. 4, 2018.
http://www.alice.cnptia.embrapa.br/alice/handle/doc/1101944
10.3390/vetsci5040098
identifier_str_mv Veterinary Sciences, v. 5, n. 4, 2018.
10.3390/vetsci5040098
url http://www.alice.cnptia.embrapa.br/alice/handle/doc/1101944
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 10 p.
dc.source.none.fl_str_mv reponame:Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron:EMBRAPA
instname_str Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron_str EMBRAPA
institution EMBRAPA
reponame_str Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
collection Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
repository.name.fl_str_mv Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
repository.mail.fl_str_mv cg-riaa@embrapa.br
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