Effect of dietary Acrocomia aculeata kernel oil rich in medium chain fatty acids on type 2 diabetic rats.

Detalhes bibliográficos
Autor(a) principal: NUNES, A. A.
Data de Publicação: 2020
Outros Autores: BUCCINI, D. F., JAQUES, J. A. dos S., PORTUGAL, L. C., GUIMARÃES, R. C. A. da, FAVARO, S. P., CALDAS, R. de A., CARVALHO, C. M. E.
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
Texto Completo: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1127820
https://doi.org/10.1016/j.jff.2020.104295
Resumo: This study evaluated the effects of dietaries formulated with kernel oil of Acrocomia aculeata (AKO), rich in medium chain fatty acids (MCFA), as partial substitute of carbohydrate calories upon blood glucose, lipid profile, insulin secretion and insulin sensitivity in diabetic rats. Overall, the dietary with any AKO dose reduced hyperglycemia, ameliorated insulin secretion, lowered insulin resistance by model HOMA-IR and HOMA-Beta and augmented pancreatic beta cells functionality, restored the number of pancreatic Beta-cell in the diabetic rats and increased it in the non-diabetic rats. In addition, AKO fed rats showed reducing triglycerides, lower density lipoprotein-cholesterol and increasing high density lipoprotein-cholesterol levels, and improved hepatic function markers. Those findings suggest AKO was effective to ameliorate the health of diabetic rats.
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spelling Effect of dietary Acrocomia aculeata kernel oil rich in medium chain fatty acids on type 2 diabetic rats.Diabetes tipo 2HiperglicemiaNutracêuticosResistência à insulinaÁcido láuricoDiabeteInsulinaMacaúbaColesterolÁcido LáticoInsulin resistanceDiabetes mellitusHyperglycemiaCholesterolThis study evaluated the effects of dietaries formulated with kernel oil of Acrocomia aculeata (AKO), rich in medium chain fatty acids (MCFA), as partial substitute of carbohydrate calories upon blood glucose, lipid profile, insulin secretion and insulin sensitivity in diabetic rats. Overall, the dietary with any AKO dose reduced hyperglycemia, ameliorated insulin secretion, lowered insulin resistance by model HOMA-IR and HOMA-Beta and augmented pancreatic beta cells functionality, restored the number of pancreatic Beta-cell in the diabetic rats and increased it in the non-diabetic rats. In addition, AKO fed rats showed reducing triglycerides, lower density lipoprotein-cholesterol and increasing high density lipoprotein-cholesterol levels, and improved hepatic function markers. Those findings suggest AKO was effective to ameliorate the health of diabetic rats.On-line first.Ângela Alves Nunes, Universidade Católica Dom Bosco; Danieli Fernanda Buccini, Universidade Catálica Dom Bosco; Jeandre Augusto dos Santos Jaques, Universidade Federal de Mato Grosso do Sul; Luciane Candeloro Portugal, Universidade Federal de Mato Grosso do Sul; Rita Cássia Avellane da Guimarães, Universidade Federal de Mato Grosso do Sul; SIMONE PALMA FAVARO, CNPAE; Ruy de Araújo Caldas, Universidade Federal de Mato Grosso do Sul; Cristiano Marcelo Espinola Carvalho, Universidade Católica Dom Bosco.NUNES, A. A.BUCCINI, D. F.JAQUES, J. A. dos S.PORTUGAL, L. C.GUIMARÃES, R. C. A. daFAVARO, S. P.CALDAS, R. de A.CARVALHO, C. M. E.2020-12-09T09:08:32Z2020-12-09T09:08:32Z2020-12-082020info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleJournal of Functional Foods, 104295, available online 25 November 2020.http://www.alice.cnptia.embrapa.br/alice/handle/doc/1127820https://doi.org/10.1016/j.jff.2020.104295porinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)instacron:EMBRAPA2020-12-09T09:08:40Zoai:www.alice.cnptia.embrapa.br:doc/1127820Repositório InstitucionalPUBhttps://www.alice.cnptia.embrapa.br/oai/requestopendoar:21542020-12-09T09:08:40falseRepositório InstitucionalPUBhttps://www.alice.cnptia.embrapa.br/oai/requestcg-riaa@embrapa.bropendoar:21542020-12-09T09:08:40Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa)false
dc.title.none.fl_str_mv Effect of dietary Acrocomia aculeata kernel oil rich in medium chain fatty acids on type 2 diabetic rats.
title Effect of dietary Acrocomia aculeata kernel oil rich in medium chain fatty acids on type 2 diabetic rats.
spellingShingle Effect of dietary Acrocomia aculeata kernel oil rich in medium chain fatty acids on type 2 diabetic rats.
NUNES, A. A.
Diabetes tipo 2
Hiperglicemia
Nutracêuticos
Resistência à insulina
Ácido láurico
Diabete
Insulina
Macaúba
Colesterol
Ácido Lático
Insulin resistance
Diabetes mellitus
Hyperglycemia
Cholesterol
title_short Effect of dietary Acrocomia aculeata kernel oil rich in medium chain fatty acids on type 2 diabetic rats.
title_full Effect of dietary Acrocomia aculeata kernel oil rich in medium chain fatty acids on type 2 diabetic rats.
title_fullStr Effect of dietary Acrocomia aculeata kernel oil rich in medium chain fatty acids on type 2 diabetic rats.
title_full_unstemmed Effect of dietary Acrocomia aculeata kernel oil rich in medium chain fatty acids on type 2 diabetic rats.
title_sort Effect of dietary Acrocomia aculeata kernel oil rich in medium chain fatty acids on type 2 diabetic rats.
author NUNES, A. A.
author_facet NUNES, A. A.
BUCCINI, D. F.
JAQUES, J. A. dos S.
PORTUGAL, L. C.
GUIMARÃES, R. C. A. da
FAVARO, S. P.
CALDAS, R. de A.
CARVALHO, C. M. E.
author_role author
author2 BUCCINI, D. F.
JAQUES, J. A. dos S.
PORTUGAL, L. C.
GUIMARÃES, R. C. A. da
FAVARO, S. P.
CALDAS, R. de A.
CARVALHO, C. M. E.
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Ângela Alves Nunes, Universidade Católica Dom Bosco; Danieli Fernanda Buccini, Universidade Catálica Dom Bosco; Jeandre Augusto dos Santos Jaques, Universidade Federal de Mato Grosso do Sul; Luciane Candeloro Portugal, Universidade Federal de Mato Grosso do Sul; Rita Cássia Avellane da Guimarães, Universidade Federal de Mato Grosso do Sul; SIMONE PALMA FAVARO, CNPAE; Ruy de Araújo Caldas, Universidade Federal de Mato Grosso do Sul; Cristiano Marcelo Espinola Carvalho, Universidade Católica Dom Bosco.
dc.contributor.author.fl_str_mv NUNES, A. A.
BUCCINI, D. F.
JAQUES, J. A. dos S.
PORTUGAL, L. C.
GUIMARÃES, R. C. A. da
FAVARO, S. P.
CALDAS, R. de A.
CARVALHO, C. M. E.
dc.subject.por.fl_str_mv Diabetes tipo 2
Hiperglicemia
Nutracêuticos
Resistência à insulina
Ácido láurico
Diabete
Insulina
Macaúba
Colesterol
Ácido Lático
Insulin resistance
Diabetes mellitus
Hyperglycemia
Cholesterol
topic Diabetes tipo 2
Hiperglicemia
Nutracêuticos
Resistência à insulina
Ácido láurico
Diabete
Insulina
Macaúba
Colesterol
Ácido Lático
Insulin resistance
Diabetes mellitus
Hyperglycemia
Cholesterol
description This study evaluated the effects of dietaries formulated with kernel oil of Acrocomia aculeata (AKO), rich in medium chain fatty acids (MCFA), as partial substitute of carbohydrate calories upon blood glucose, lipid profile, insulin secretion and insulin sensitivity in diabetic rats. Overall, the dietary with any AKO dose reduced hyperglycemia, ameliorated insulin secretion, lowered insulin resistance by model HOMA-IR and HOMA-Beta and augmented pancreatic beta cells functionality, restored the number of pancreatic Beta-cell in the diabetic rats and increased it in the non-diabetic rats. In addition, AKO fed rats showed reducing triglycerides, lower density lipoprotein-cholesterol and increasing high density lipoprotein-cholesterol levels, and improved hepatic function markers. Those findings suggest AKO was effective to ameliorate the health of diabetic rats.
publishDate 2020
dc.date.none.fl_str_mv 2020-12-09T09:08:32Z
2020-12-09T09:08:32Z
2020-12-08
2020
dc.type.driver.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv Journal of Functional Foods, 104295, available online 25 November 2020.
http://www.alice.cnptia.embrapa.br/alice/handle/doc/1127820
https://doi.org/10.1016/j.jff.2020.104295
identifier_str_mv Journal of Functional Foods, 104295, available online 25 November 2020.
url http://www.alice.cnptia.embrapa.br/alice/handle/doc/1127820
https://doi.org/10.1016/j.jff.2020.104295
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron:EMBRAPA
instname_str Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron_str EMBRAPA
institution EMBRAPA
reponame_str Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
collection Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
repository.name.fl_str_mv Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
repository.mail.fl_str_mv cg-riaa@embrapa.br
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