Selection signatures in Canchim beef cattle.

• Autor(a) principal: URBITANI, I.
• Data de Publicação: 2014
• Outros Autores: BUZANSKAS, M. E., CHUD, T. C. S., MORKRY, F. B, REGITANO, L. C. A., HIGA, R. H., MUNARI, D. P.
• Idioma: eng
• Título da fonte: Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
• Texto Completo: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1003696
• topic: Polimorfismo de nucleotídeo único; Gado de corte; Beef cattle; Single nucleotide polymorphism

Selection signature (SS) was assessed in this study by means of the integrated haplotype score (iHS) method, which determines the decay of homozygosity in the surroundings of a core single nucleotide polymorphism (SNP) marker. Canchim breed animals were genotyped using the Illumina BovineHD BeadChip; which has almost 800 thousand SNP markers. Genotype quality control (QC) was applied to exclude SNP with genotype calling score lower than 0.20; SNP with minor allele frequency lower than 0.01; and call rate for SNP and samples which were lower than 0.95 and 0.90, respectively. Only autosomal SNPs with known genome position were used. After the QC, 687,655 SNPs and 396 samples remained for SS analysis. Signals of SS were detected on chromosomes 5, 6, 8, and 14, indicating that these regions are conserved through recent generations.