Variants in myostatin and MyoD family genes are associated with meat quality traits in Santa Inês. sheep
Autor(a) principal: | |
---|---|
Data de Publicação: | 2020 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) |
Texto Completo: | http://www.alice.cnptia.embrapa.br/alice/handle/doc/1128726 https://doi.org/10.1080/10495398.2020.1781651 |
Resumo: | Myostatin and MyoD family genes play vital roles in myogenesis and this study aimed to identify association of variants in MyoD1, MyoG, MyF5, MyF6, and MSTN genes with meat traits in Santa Inês sheep. A dataset with 44 variants and records of seven meat traits in 192 lambs (pH0, pH24, a, b, L, tenderness assessed by shear force, and water-holding capacity) was used. Single-locus and haplotype association analyses were performed, and the significance threshold was established according to Bonferroni?s method. Single-locus analysis revealed two associations at a Bonferroni level, where the variant c.935-185C > G in MyoD1 had an additive effect (4.31 ± 1.08 N) on tenderness, while the variant c.464 þ 185G > A in MyoG had an additive effect (2.86 ± 0.64) on a. Additionally, the haplotype replacement GT>AC in MSTN was associated with pH0 (1.26 ± 0.31), pH24 (1.07 ± 0.27), a (1.40 ± 0.51), and tenderness (3.83 ± 1.22 N), while the replacement GT > AG in MyoD1 was associated with pH0 (1.43 ± 0.26), pH24 (1.25 ± 0.22), b (1.06 ± 0.39), and tenderness (4.13 ± 1.16 N). Our results have demonstrated that some variants in MyoG, MyF6, MyoD1, and MSTN can be associated with physicochemical meat traits in Santa In^êes sheep. |
id |
EMBR_b52989b906c41f9fd6c99c0bcc638bcf |
---|---|
oai_identifier_str |
oai:www.alice.cnptia.embrapa.br:doc/1128726 |
network_acronym_str |
EMBR |
network_name_str |
Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) |
repository_id_str |
2154 |
spelling |
Variants in myostatin and MyoD family genes are associated with meat quality traits in Santa Inês. sheepSanta InêsOvinoOvinoculturaCarneSheepLamb meatLambsMyostatin and MyoD family genes play vital roles in myogenesis and this study aimed to identify association of variants in MyoD1, MyoG, MyF5, MyF6, and MSTN genes with meat traits in Santa Inês sheep. A dataset with 44 variants and records of seven meat traits in 192 lambs (pH0, pH24, a, b, L, tenderness assessed by shear force, and water-holding capacity) was used. Single-locus and haplotype association analyses were performed, and the significance threshold was established according to Bonferroni?s method. Single-locus analysis revealed two associations at a Bonferroni level, where the variant c.935-185C > G in MyoD1 had an additive effect (4.31 ± 1.08 N) on tenderness, while the variant c.464 þ 185G > A in MyoG had an additive effect (2.86 ± 0.64) on a. Additionally, the haplotype replacement GT>AC in MSTN was associated with pH0 (1.26 ± 0.31), pH24 (1.07 ± 0.27), a (1.40 ± 0.51), and tenderness (3.83 ± 1.22 N), while the replacement GT > AG in MyoD1 was associated with pH0 (1.43 ± 0.26), pH24 (1.25 ± 0.22), b (1.06 ± 0.39), and tenderness (4.13 ± 1.16 N). Our results have demonstrated that some variants in MyoG, MyF6, MyoD1, and MSTN can be associated with physicochemical meat traits in Santa In^êes sheep.Epub. 7 Jul. 2020.LUIS PAULO BATISTA SOUSA JUNIORARIANA NASCIMENTO MEIRAHYMERSON COSTA AZEVEDO, CPATCEVANDRO NEVES MUNIZ, CPATCLUIZ LEHMANN COUTINHOGERSON BARRETO MOURAOANDRE GUSTAVO LEAOVICTOR BRENO PEDROSALUIS FERNANDO BATISTA PINTO.SOUSA JUNIOR, L. P. B.MEIRA, A. N.AZEVEDO, H. C.MUNIZ, E. N.COUTINHO, L. L.MOURAO, G. B.LEAO, A. G.PEDROSA, V. B.PINTO, L. F. B.2020-12-28T09:04:51Z2020-12-28T09:04:51Z2020-12-272022info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleAnimal Biotechnology, v. 33, n. 2, p. 201-213, Apr. 2022.http://www.alice.cnptia.embrapa.br/alice/handle/doc/1128726https://doi.org/10.1080/10495398.2020.1781651enginfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)instacron:EMBRAPA2020-12-28T09:04:59Zoai:www.alice.cnptia.embrapa.br:doc/1128726Repositório InstitucionalPUBhttps://www.alice.cnptia.embrapa.br/oai/requestopendoar:21542020-12-28T09:04:59falseRepositório InstitucionalPUBhttps://www.alice.cnptia.embrapa.br/oai/requestcg-riaa@embrapa.bropendoar:21542020-12-28T09:04:59Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa)false |
dc.title.none.fl_str_mv |
Variants in myostatin and MyoD family genes are associated with meat quality traits in Santa Inês. sheep |
title |
Variants in myostatin and MyoD family genes are associated with meat quality traits in Santa Inês. sheep |
spellingShingle |
Variants in myostatin and MyoD family genes are associated with meat quality traits in Santa Inês. sheep SOUSA JUNIOR, L. P. B. Santa Inês Ovino Ovinocultura Carne Sheep Lamb meat Lambs |
title_short |
Variants in myostatin and MyoD family genes are associated with meat quality traits in Santa Inês. sheep |
title_full |
Variants in myostatin and MyoD family genes are associated with meat quality traits in Santa Inês. sheep |
title_fullStr |
Variants in myostatin and MyoD family genes are associated with meat quality traits in Santa Inês. sheep |
title_full_unstemmed |
Variants in myostatin and MyoD family genes are associated with meat quality traits in Santa Inês. sheep |
title_sort |
Variants in myostatin and MyoD family genes are associated with meat quality traits in Santa Inês. sheep |
author |
SOUSA JUNIOR, L. P. B. |
author_facet |
SOUSA JUNIOR, L. P. B. MEIRA, A. N. AZEVEDO, H. C. MUNIZ, E. N. COUTINHO, L. L. MOURAO, G. B. LEAO, A. G. PEDROSA, V. B. PINTO, L. F. B. |
author_role |
author |
author2 |
MEIRA, A. N. AZEVEDO, H. C. MUNIZ, E. N. COUTINHO, L. L. MOURAO, G. B. LEAO, A. G. PEDROSA, V. B. PINTO, L. F. B. |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
LUIS PAULO BATISTA SOUSA JUNIOR ARIANA NASCIMENTO MEIRA HYMERSON COSTA AZEVEDO, CPATC EVANDRO NEVES MUNIZ, CPATC LUIZ LEHMANN COUTINHO GERSON BARRETO MOURAO ANDRE GUSTAVO LEAO VICTOR BRENO PEDROSA LUIS FERNANDO BATISTA PINTO. |
dc.contributor.author.fl_str_mv |
SOUSA JUNIOR, L. P. B. MEIRA, A. N. AZEVEDO, H. C. MUNIZ, E. N. COUTINHO, L. L. MOURAO, G. B. LEAO, A. G. PEDROSA, V. B. PINTO, L. F. B. |
dc.subject.por.fl_str_mv |
Santa Inês Ovino Ovinocultura Carne Sheep Lamb meat Lambs |
topic |
Santa Inês Ovino Ovinocultura Carne Sheep Lamb meat Lambs |
description |
Myostatin and MyoD family genes play vital roles in myogenesis and this study aimed to identify association of variants in MyoD1, MyoG, MyF5, MyF6, and MSTN genes with meat traits in Santa Inês sheep. A dataset with 44 variants and records of seven meat traits in 192 lambs (pH0, pH24, a, b, L, tenderness assessed by shear force, and water-holding capacity) was used. Single-locus and haplotype association analyses were performed, and the significance threshold was established according to Bonferroni?s method. Single-locus analysis revealed two associations at a Bonferroni level, where the variant c.935-185C > G in MyoD1 had an additive effect (4.31 ± 1.08 N) on tenderness, while the variant c.464 þ 185G > A in MyoG had an additive effect (2.86 ± 0.64) on a. Additionally, the haplotype replacement GT>AC in MSTN was associated with pH0 (1.26 ± 0.31), pH24 (1.07 ± 0.27), a (1.40 ± 0.51), and tenderness (3.83 ± 1.22 N), while the replacement GT > AG in MyoD1 was associated with pH0 (1.43 ± 0.26), pH24 (1.25 ± 0.22), b (1.06 ± 0.39), and tenderness (4.13 ± 1.16 N). Our results have demonstrated that some variants in MyoG, MyF6, MyoD1, and MSTN can be associated with physicochemical meat traits in Santa In^êes sheep. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-28T09:04:51Z 2020-12-28T09:04:51Z 2020-12-27 2022 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
Animal Biotechnology, v. 33, n. 2, p. 201-213, Apr. 2022. http://www.alice.cnptia.embrapa.br/alice/handle/doc/1128726 https://doi.org/10.1080/10495398.2020.1781651 |
identifier_str_mv |
Animal Biotechnology, v. 33, n. 2, p. 201-213, Apr. 2022. |
url |
http://www.alice.cnptia.embrapa.br/alice/handle/doc/1128726 https://doi.org/10.1080/10495398.2020.1781651 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa) instacron:EMBRAPA |
instname_str |
Empresa Brasileira de Pesquisa Agropecuária (Embrapa) |
instacron_str |
EMBRAPA |
institution |
EMBRAPA |
reponame_str |
Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) |
collection |
Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) |
repository.name.fl_str_mv |
Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa) |
repository.mail.fl_str_mv |
cg-riaa@embrapa.br |
_version_ |
1794503500265160704 |