Variants in myostatin and MyoD family genes are associated with meat quality traits in Santa Inês. sheep

Detalhes bibliográficos
Autor(a) principal: SOUSA JUNIOR, L. P. B.
Data de Publicação: 2020
Outros Autores: MEIRA, A. N., AZEVEDO, H. C., MUNIZ, E. N., COUTINHO, L. L., MOURAO, G. B., LEAO, A. G., PEDROSA, V. B., PINTO, L. F. B.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
Texto Completo: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1128726
https://doi.org/10.1080/10495398.2020.1781651
Resumo: Myostatin and MyoD family genes play vital roles in myogenesis and this study aimed to identify association of variants in MyoD1, MyoG, MyF5, MyF6, and MSTN genes with meat traits in Santa Inês sheep. A dataset with 44 variants and records of seven meat traits in 192 lambs (pH0, pH24, a, b, L, tenderness assessed by shear force, and water-holding capacity) was used. Single-locus and haplotype association analyses were performed, and the significance threshold was established according to Bonferroni?s method. Single-locus analysis revealed two associations at a Bonferroni level, where the variant c.935-185C > G in MyoD1 had an additive effect (4.31 ± 1.08 N) on tenderness, while the variant c.464 þ 185G > A in MyoG had an additive effect (2.86 ± 0.64) on a. Additionally, the haplotype replacement GT>AC in MSTN was associated with pH0 (1.26 ± 0.31), pH24 (1.07 ± 0.27), a (1.40 ± 0.51), and tenderness (3.83 ± 1.22 N), while the replacement GT > AG in MyoD1 was associated with pH0 (1.43 ± 0.26), pH24 (1.25 ± 0.22), b (1.06 ± 0.39), and tenderness (4.13 ± 1.16 N). Our results have demonstrated that some variants in MyoG, MyF6, MyoD1, and MSTN can be associated with physicochemical meat traits in Santa In^êes sheep.
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spelling Variants in myostatin and MyoD family genes are associated with meat quality traits in Santa Inês. sheepSanta InêsOvinoOvinoculturaCarneSheepLamb meatLambsMyostatin and MyoD family genes play vital roles in myogenesis and this study aimed to identify association of variants in MyoD1, MyoG, MyF5, MyF6, and MSTN genes with meat traits in Santa Inês sheep. A dataset with 44 variants and records of seven meat traits in 192 lambs (pH0, pH24, a, b, L, tenderness assessed by shear force, and water-holding capacity) was used. Single-locus and haplotype association analyses were performed, and the significance threshold was established according to Bonferroni?s method. Single-locus analysis revealed two associations at a Bonferroni level, where the variant c.935-185C > G in MyoD1 had an additive effect (4.31 ± 1.08 N) on tenderness, while the variant c.464 þ 185G > A in MyoG had an additive effect (2.86 ± 0.64) on a. Additionally, the haplotype replacement GT>AC in MSTN was associated with pH0 (1.26 ± 0.31), pH24 (1.07 ± 0.27), a (1.40 ± 0.51), and tenderness (3.83 ± 1.22 N), while the replacement GT > AG in MyoD1 was associated with pH0 (1.43 ± 0.26), pH24 (1.25 ± 0.22), b (1.06 ± 0.39), and tenderness (4.13 ± 1.16 N). Our results have demonstrated that some variants in MyoG, MyF6, MyoD1, and MSTN can be associated with physicochemical meat traits in Santa In^êes sheep.Epub. 7 Jul. 2020.LUIS PAULO BATISTA SOUSA JUNIORARIANA NASCIMENTO MEIRAHYMERSON COSTA AZEVEDO, CPATCEVANDRO NEVES MUNIZ, CPATCLUIZ LEHMANN COUTINHOGERSON BARRETO MOURAOANDRE GUSTAVO LEAOVICTOR BRENO PEDROSALUIS FERNANDO BATISTA PINTO.SOUSA JUNIOR, L. P. B.MEIRA, A. N.AZEVEDO, H. C.MUNIZ, E. N.COUTINHO, L. L.MOURAO, G. B.LEAO, A. G.PEDROSA, V. B.PINTO, L. F. B.2020-12-28T09:04:51Z2020-12-28T09:04:51Z2020-12-272022info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleAnimal Biotechnology, v. 33, n. 2, p. 201-213, Apr. 2022.http://www.alice.cnptia.embrapa.br/alice/handle/doc/1128726https://doi.org/10.1080/10495398.2020.1781651enginfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)instacron:EMBRAPA2020-12-28T09:04:59Zoai:www.alice.cnptia.embrapa.br:doc/1128726Repositório InstitucionalPUBhttps://www.alice.cnptia.embrapa.br/oai/requestopendoar:21542020-12-28T09:04:59falseRepositório InstitucionalPUBhttps://www.alice.cnptia.embrapa.br/oai/requestcg-riaa@embrapa.bropendoar:21542020-12-28T09:04:59Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa)false
dc.title.none.fl_str_mv Variants in myostatin and MyoD family genes are associated with meat quality traits in Santa Inês. sheep
title Variants in myostatin and MyoD family genes are associated with meat quality traits in Santa Inês. sheep
spellingShingle Variants in myostatin and MyoD family genes are associated with meat quality traits in Santa Inês. sheep
SOUSA JUNIOR, L. P. B.
Santa Inês
Ovino
Ovinocultura
Carne
Sheep
Lamb meat
Lambs
title_short Variants in myostatin and MyoD family genes are associated with meat quality traits in Santa Inês. sheep
title_full Variants in myostatin and MyoD family genes are associated with meat quality traits in Santa Inês. sheep
title_fullStr Variants in myostatin and MyoD family genes are associated with meat quality traits in Santa Inês. sheep
title_full_unstemmed Variants in myostatin and MyoD family genes are associated with meat quality traits in Santa Inês. sheep
title_sort Variants in myostatin and MyoD family genes are associated with meat quality traits in Santa Inês. sheep
author SOUSA JUNIOR, L. P. B.
author_facet SOUSA JUNIOR, L. P. B.
MEIRA, A. N.
AZEVEDO, H. C.
MUNIZ, E. N.
COUTINHO, L. L.
MOURAO, G. B.
LEAO, A. G.
PEDROSA, V. B.
PINTO, L. F. B.
author_role author
author2 MEIRA, A. N.
AZEVEDO, H. C.
MUNIZ, E. N.
COUTINHO, L. L.
MOURAO, G. B.
LEAO, A. G.
PEDROSA, V. B.
PINTO, L. F. B.
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv LUIS PAULO BATISTA SOUSA JUNIOR
ARIANA NASCIMENTO MEIRA
HYMERSON COSTA AZEVEDO, CPATC
EVANDRO NEVES MUNIZ, CPATC
LUIZ LEHMANN COUTINHO
GERSON BARRETO MOURAO
ANDRE GUSTAVO LEAO
VICTOR BRENO PEDROSA
LUIS FERNANDO BATISTA PINTO.
dc.contributor.author.fl_str_mv SOUSA JUNIOR, L. P. B.
MEIRA, A. N.
AZEVEDO, H. C.
MUNIZ, E. N.
COUTINHO, L. L.
MOURAO, G. B.
LEAO, A. G.
PEDROSA, V. B.
PINTO, L. F. B.
dc.subject.por.fl_str_mv Santa Inês
Ovino
Ovinocultura
Carne
Sheep
Lamb meat
Lambs
topic Santa Inês
Ovino
Ovinocultura
Carne
Sheep
Lamb meat
Lambs
description Myostatin and MyoD family genes play vital roles in myogenesis and this study aimed to identify association of variants in MyoD1, MyoG, MyF5, MyF6, and MSTN genes with meat traits in Santa Inês sheep. A dataset with 44 variants and records of seven meat traits in 192 lambs (pH0, pH24, a, b, L, tenderness assessed by shear force, and water-holding capacity) was used. Single-locus and haplotype association analyses were performed, and the significance threshold was established according to Bonferroni?s method. Single-locus analysis revealed two associations at a Bonferroni level, where the variant c.935-185C > G in MyoD1 had an additive effect (4.31 ± 1.08 N) on tenderness, while the variant c.464 þ 185G > A in MyoG had an additive effect (2.86 ± 0.64) on a. Additionally, the haplotype replacement GT>AC in MSTN was associated with pH0 (1.26 ± 0.31), pH24 (1.07 ± 0.27), a (1.40 ± 0.51), and tenderness (3.83 ± 1.22 N), while the replacement GT > AG in MyoD1 was associated with pH0 (1.43 ± 0.26), pH24 (1.25 ± 0.22), b (1.06 ± 0.39), and tenderness (4.13 ± 1.16 N). Our results have demonstrated that some variants in MyoG, MyF6, MyoD1, and MSTN can be associated with physicochemical meat traits in Santa In^êes sheep.
publishDate 2020
dc.date.none.fl_str_mv 2020-12-28T09:04:51Z
2020-12-28T09:04:51Z
2020-12-27
2022
dc.type.driver.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv Animal Biotechnology, v. 33, n. 2, p. 201-213, Apr. 2022.
http://www.alice.cnptia.embrapa.br/alice/handle/doc/1128726
https://doi.org/10.1080/10495398.2020.1781651
identifier_str_mv Animal Biotechnology, v. 33, n. 2, p. 201-213, Apr. 2022.
url http://www.alice.cnptia.embrapa.br/alice/handle/doc/1128726
https://doi.org/10.1080/10495398.2020.1781651
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron:EMBRAPA
instname_str Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron_str EMBRAPA
institution EMBRAPA
reponame_str Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
collection Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
repository.name.fl_str_mv Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
repository.mail.fl_str_mv cg-riaa@embrapa.br
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