Occurrence of bufotenin in the Osteocephalus genus (Anura: Hylidae).

Detalhes bibliográficos
Autor(a) principal: COSTA, T. O. G.
Data de Publicação: 2005
Outros Autores: MORALES, R. A. V., BRITO, J. P., GORDO, M., PINTO, A. C., BLOCH JUNIOR, C.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
Texto Completo: http://www.alice.cnptia.embrapa.br/alice/handle/doc/186052
Resumo: Bufotenin (5-hydroxy-N,N-dimetyltryptamine) is a tryptamine alkaloid widely spread among anuran families as a component of their chemical defense system, acting as a potent hallucinogenic factor, showing similar activity to LSD upon interaction with the 5HT2 human receptor. This work demonstrates the presence of bufotenin in the skin secretion of three arboreal amphibian species of the Osteocephalus genus (Osteocephalus taurinus, Osteocephalus oophagus and Osteocephalus langsdorffii) from the Amazon and the Atlantic rain forests using RP-HPLC, ESI-MS/MS, UV, IR and multidimensional NMR techniques. To our knowledge, this is the first description of bufotenin in the Osteocephalus genus, so far.
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spelling Occurrence of bufotenin in the Osteocephalus genus (Anura: Hylidae).BufoteninOsteocephalusTryptamine alkaloidBufotenin (5-hydroxy-N,N-dimetyltryptamine) is a tryptamine alkaloid widely spread among anuran families as a component of their chemical defense system, acting as a potent hallucinogenic factor, showing similar activity to LSD upon interaction with the 5HT2 human receptor. This work demonstrates the presence of bufotenin in the skin secretion of three arboreal amphibian species of the Osteocephalus genus (Osteocephalus taurinus, Osteocephalus oophagus and Osteocephalus langsdorffii) from the Amazon and the Atlantic rain forests using RP-HPLC, ESI-MS/MS, UV, IR and multidimensional NMR techniques. To our knowledge, this is the first description of bufotenin in the Osteocephalus genus, so far.2018-06-11T16:58:59Z2018-06-11T16:58:59Z2005-08-3020052018-06-11T16:58:59Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleToxicon, v. 46, n. 4, p. 371-374, 2005.http://www.alice.cnptia.embrapa.br/alice/handle/doc/186052engCOSTA, T. O. G.MORALES, R. A. V.BRITO, J. P.GORDO, M.PINTO, A. C.BLOCH JUNIOR, C.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)instacron:EMBRAPA2018-06-11T16:59:05Zoai:www.alice.cnptia.embrapa.br:doc/186052Repositório InstitucionalPUBhttps://www.alice.cnptia.embrapa.br/oai/requestopendoar:21542018-06-11T16:59:05falseRepositório InstitucionalPUBhttps://www.alice.cnptia.embrapa.br/oai/requestcg-riaa@embrapa.bropendoar:21542018-06-11T16:59:05Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa)false
dc.title.none.fl_str_mv Occurrence of bufotenin in the Osteocephalus genus (Anura: Hylidae).
title Occurrence of bufotenin in the Osteocephalus genus (Anura: Hylidae).
spellingShingle Occurrence of bufotenin in the Osteocephalus genus (Anura: Hylidae).
COSTA, T. O. G.
Bufotenin
Osteocephalus
Tryptamine alkaloid
title_short Occurrence of bufotenin in the Osteocephalus genus (Anura: Hylidae).
title_full Occurrence of bufotenin in the Osteocephalus genus (Anura: Hylidae).
title_fullStr Occurrence of bufotenin in the Osteocephalus genus (Anura: Hylidae).
title_full_unstemmed Occurrence of bufotenin in the Osteocephalus genus (Anura: Hylidae).
title_sort Occurrence of bufotenin in the Osteocephalus genus (Anura: Hylidae).
author COSTA, T. O. G.
author_facet COSTA, T. O. G.
MORALES, R. A. V.
BRITO, J. P.
GORDO, M.
PINTO, A. C.
BLOCH JUNIOR, C.
author_role author
author2 MORALES, R. A. V.
BRITO, J. P.
GORDO, M.
PINTO, A. C.
BLOCH JUNIOR, C.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv COSTA, T. O. G.
MORALES, R. A. V.
BRITO, J. P.
GORDO, M.
PINTO, A. C.
BLOCH JUNIOR, C.
dc.subject.por.fl_str_mv Bufotenin
Osteocephalus
Tryptamine alkaloid
topic Bufotenin
Osteocephalus
Tryptamine alkaloid
description Bufotenin (5-hydroxy-N,N-dimetyltryptamine) is a tryptamine alkaloid widely spread among anuran families as a component of their chemical defense system, acting as a potent hallucinogenic factor, showing similar activity to LSD upon interaction with the 5HT2 human receptor. This work demonstrates the presence of bufotenin in the skin secretion of three arboreal amphibian species of the Osteocephalus genus (Osteocephalus taurinus, Osteocephalus oophagus and Osteocephalus langsdorffii) from the Amazon and the Atlantic rain forests using RP-HPLC, ESI-MS/MS, UV, IR and multidimensional NMR techniques. To our knowledge, this is the first description of bufotenin in the Osteocephalus genus, so far.
publishDate 2005
dc.date.none.fl_str_mv 2005-08-30
2005
2018-06-11T16:58:59Z
2018-06-11T16:58:59Z
2018-06-11T16:58:59Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv Toxicon, v. 46, n. 4, p. 371-374, 2005.
http://www.alice.cnptia.embrapa.br/alice/handle/doc/186052
identifier_str_mv Toxicon, v. 46, n. 4, p. 371-374, 2005.
url http://www.alice.cnptia.embrapa.br/alice/handle/doc/186052
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.source.none.fl_str_mv reponame:Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron:EMBRAPA
instname_str Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron_str EMBRAPA
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reponame_str Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
collection Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
repository.name.fl_str_mv Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
repository.mail.fl_str_mv cg-riaa@embrapa.br
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