In vitro cytocidal effects of the essential oil from Croton cajucara (red sacaca) and its major constituent 7- hydroxycalamenene against Leishmania chagasi.

Detalhes bibliográficos
Autor(a) principal: RODRIGUES, I. A.
Data de Publicação: 2013
Outros Autores: AZEVEDO, M. M. B., CHAVES, F. C. M., BIZZO, H. R., CORTE-REAL, S., ALVIANO, D. S., ALVIANO, C. S., ROSA, M. S. S., VERMELHO, A. B.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
Texto Completo: http://www.alice.cnptia.embrapa.br/alice/handle/doc/967883
Resumo: Visceral leishmaniasis is the most serious form of leishmaniasis and can be lethal if left untreated. Currently available treatments for these parasitic diseases are frequently associated to severe side effects. The leaves of Croton cajucara are used as an infusion in popular medicine to combat several diseases. Previous studies have demonstrated that the linalool-rich essential oil from C. cajucara (white sacaca) is extremely efficient against the tegumentary specie Leishmania amazonensis. In this study, we investigated the effects of the 7-hydroxycalamenene-rich essential oil from the leaves of C. cajucara (red sacaca) against Leishmania chagasi, as well as on the interaction of these parasites with host cells.
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spelling In vitro cytocidal effects of the essential oil from Croton cajucara (red sacaca) and its major constituent 7- hydroxycalamenene against Leishmania chagasi.SacacaVisceral leishmaniasis is the most serious form of leishmaniasis and can be lethal if left untreated. Currently available treatments for these parasitic diseases are frequently associated to severe side effects. The leaves of Croton cajucara are used as an infusion in popular medicine to combat several diseases. Previous studies have demonstrated that the linalool-rich essential oil from C. cajucara (white sacaca) is extremely efficient against the tegumentary specie Leishmania amazonensis. In this study, we investigated the effects of the 7-hydroxycalamenene-rich essential oil from the leaves of C. cajucara (red sacaca) against Leishmania chagasi, as well as on the interaction of these parasites with host cells.IGOR A. RODRIGUES, UFRJ; MARIANA M. B. AZEVEDO, UFRJ; FRANCISCO CELIO MAIA CHAVES, CPAA; HUMBERTO RIBEIRO BIZZO, CTAA; Suzana Corte-Real, Instituto Oswaldo Cruz; Daniela S. Alviano, UFRJ; Celuta S Alviano, UFRJ; Maria S S Rosa, UFRJ; Alane B. Vermelho, UFRJ.RODRIGUES, I. A.AZEVEDO, M. M. B.CHAVES, F. C. M.BIZZO, H. R.CORTE-REAL, S.ALVIANO, D. S.ALVIANO, C. S.ROSA, M. S. S.VERMELHO, A. B.2013-10-07T11:11:11Z2013-10-07T11:11:11Z2013-10-0720132014-02-12T11:11:11Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleBMC Complementary and Alternative Medicine, v. 13, n. 1, p. 249, Oct. 2013.http://www.alice.cnptia.embrapa.br/alice/handle/doc/96788310.1186/1472-6882-13-249enginfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)instacron:EMBRAPA2017-08-16T00:04:00Zoai:www.alice.cnptia.embrapa.br:doc/967883Repositório InstitucionalPUBhttps://www.alice.cnptia.embrapa.br/oai/requestopendoar:21542017-08-16T00:04falseRepositório InstitucionalPUBhttps://www.alice.cnptia.embrapa.br/oai/requestcg-riaa@embrapa.bropendoar:21542017-08-16T00:04Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa)false
dc.title.none.fl_str_mv In vitro cytocidal effects of the essential oil from Croton cajucara (red sacaca) and its major constituent 7- hydroxycalamenene against Leishmania chagasi.
title In vitro cytocidal effects of the essential oil from Croton cajucara (red sacaca) and its major constituent 7- hydroxycalamenene against Leishmania chagasi.
spellingShingle In vitro cytocidal effects of the essential oil from Croton cajucara (red sacaca) and its major constituent 7- hydroxycalamenene against Leishmania chagasi.
RODRIGUES, I. A.
Sacaca
title_short In vitro cytocidal effects of the essential oil from Croton cajucara (red sacaca) and its major constituent 7- hydroxycalamenene against Leishmania chagasi.
title_full In vitro cytocidal effects of the essential oil from Croton cajucara (red sacaca) and its major constituent 7- hydroxycalamenene against Leishmania chagasi.
title_fullStr In vitro cytocidal effects of the essential oil from Croton cajucara (red sacaca) and its major constituent 7- hydroxycalamenene against Leishmania chagasi.
title_full_unstemmed In vitro cytocidal effects of the essential oil from Croton cajucara (red sacaca) and its major constituent 7- hydroxycalamenene against Leishmania chagasi.
title_sort In vitro cytocidal effects of the essential oil from Croton cajucara (red sacaca) and its major constituent 7- hydroxycalamenene against Leishmania chagasi.
author RODRIGUES, I. A.
author_facet RODRIGUES, I. A.
AZEVEDO, M. M. B.
CHAVES, F. C. M.
BIZZO, H. R.
CORTE-REAL, S.
ALVIANO, D. S.
ALVIANO, C. S.
ROSA, M. S. S.
VERMELHO, A. B.
author_role author
author2 AZEVEDO, M. M. B.
CHAVES, F. C. M.
BIZZO, H. R.
CORTE-REAL, S.
ALVIANO, D. S.
ALVIANO, C. S.
ROSA, M. S. S.
VERMELHO, A. B.
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv IGOR A. RODRIGUES, UFRJ; MARIANA M. B. AZEVEDO, UFRJ; FRANCISCO CELIO MAIA CHAVES, CPAA; HUMBERTO RIBEIRO BIZZO, CTAA; Suzana Corte-Real, Instituto Oswaldo Cruz; Daniela S. Alviano, UFRJ; Celuta S Alviano, UFRJ; Maria S S Rosa, UFRJ; Alane B. Vermelho, UFRJ.
dc.contributor.author.fl_str_mv RODRIGUES, I. A.
AZEVEDO, M. M. B.
CHAVES, F. C. M.
BIZZO, H. R.
CORTE-REAL, S.
ALVIANO, D. S.
ALVIANO, C. S.
ROSA, M. S. S.
VERMELHO, A. B.
dc.subject.por.fl_str_mv Sacaca
topic Sacaca
description Visceral leishmaniasis is the most serious form of leishmaniasis and can be lethal if left untreated. Currently available treatments for these parasitic diseases are frequently associated to severe side effects. The leaves of Croton cajucara are used as an infusion in popular medicine to combat several diseases. Previous studies have demonstrated that the linalool-rich essential oil from C. cajucara (white sacaca) is extremely efficient against the tegumentary specie Leishmania amazonensis. In this study, we investigated the effects of the 7-hydroxycalamenene-rich essential oil from the leaves of C. cajucara (red sacaca) against Leishmania chagasi, as well as on the interaction of these parasites with host cells.
publishDate 2013
dc.date.none.fl_str_mv 2013-10-07T11:11:11Z
2013-10-07T11:11:11Z
2013-10-07
2013
2014-02-12T11:11:11Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv BMC Complementary and Alternative Medicine, v. 13, n. 1, p. 249, Oct. 2013.
http://www.alice.cnptia.embrapa.br/alice/handle/doc/967883
10.1186/1472-6882-13-249
identifier_str_mv BMC Complementary and Alternative Medicine, v. 13, n. 1, p. 249, Oct. 2013.
10.1186/1472-6882-13-249
url http://www.alice.cnptia.embrapa.br/alice/handle/doc/967883
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron:EMBRAPA
instname_str Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron_str EMBRAPA
institution EMBRAPA
reponame_str Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
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