Malignant peripheral nerve sheath tumor - a case report and review
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Health Residencies Journal (HRJ) |
Texto Completo: | https://escsresidencias.emnuvens.com.br/hrj/article/view/1 |
Resumo: | This case report aims to contribute to the understanding and to present a new look on the treatment of a rare, aggressive and poorly understood pathology, known as malignant tumor of the peripheral nerve myelin sheath. The objective of this research is to help building a better understanding of this pathology and to evaluate what is new in diagnosis and treatment. We used PubMed’s articles with the descriptors: malignant peripheral nerve sheath tumor, Ki67, and malignant tumor immunohistochemistry of the peripheral nerve sheath. 17 articles were selected. We also used the descriptor “sarcoma staging” for the visualization of a book chapter and a journal. Malignant neoplasm of the peripheral nerve myelin sheath is a disease that mainly affects neurofibromatosis-1 or patients with prior radiotherapy, but may occur randomly, as with the patient in question. Due to illness multiple incidence locations, the symptoms may be late and staging is difficult. The staging is performed taking into account the size of the primary tumor, its location, lymph node involvement, presence of distant metastases and degree of cell differentiation. The diagnosis is made after resection of the piece with anatomopathological and immunohistochemical analysis, which may delay the treatment. Therefore, it has been seen that the most common treatment continues to be complete surgery with free margins, but there are promising studies in the genetics field for the treatment and better understanding of this pathology |
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Malignant peripheral nerve sheath tumor - a case report and reviewMalignant peripheral nerve sheath tumorstagingKi67s100This case report aims to contribute to the understanding and to present a new look on the treatment of a rare, aggressive and poorly understood pathology, known as malignant tumor of the peripheral nerve myelin sheath. The objective of this research is to help building a better understanding of this pathology and to evaluate what is new in diagnosis and treatment. We used PubMed’s articles with the descriptors: malignant peripheral nerve sheath tumor, Ki67, and malignant tumor immunohistochemistry of the peripheral nerve sheath. 17 articles were selected. We also used the descriptor “sarcoma staging” for the visualization of a book chapter and a journal. Malignant neoplasm of the peripheral nerve myelin sheath is a disease that mainly affects neurofibromatosis-1 or patients with prior radiotherapy, but may occur randomly, as with the patient in question. Due to illness multiple incidence locations, the symptoms may be late and staging is difficult. The staging is performed taking into account the size of the primary tumor, its location, lymph node involvement, presence of distant metastases and degree of cell differentiation. The diagnosis is made after resection of the piece with anatomopathological and immunohistochemical analysis, which may delay the treatment. Therefore, it has been seen that the most common treatment continues to be complete surgery with free margins, but there are promising studies in the genetics field for the treatment and better understanding of this pathologyCoordenação de Pós-Graduação lato sensu e Extensão da Escola Superior de Ciências da Saúde2020-05-16info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://escsresidencias.emnuvens.com.br/hrj/article/view/110.51723/hrj.v1i3.1Health Residencies Journal - HRJ; v. 1 n. 3 (2020): Desafios em tempo de Pandemia; 16-272675-2913reponame:Health Residencies Journal (HRJ)instname:Escola Superior de Ciências da Saúde (ESCS)instacron:ESCSporhttps://escsresidencias.emnuvens.com.br/hrj/article/view/1/24Copyright (c) 2020 Health Residencies Journal - HRJinfo:eu-repo/semantics/openAccessRabelo Gonzalez Veldman, DanielleBatista da Mota, Fernando Henrique Ribeiro Vieira, Laís Carrijo dos Santo, Igor Diego Araújo Marques, Anna Carolina Roma Rodrigues, Alessandra Monteiro da Silva Veldman, Pieter 2021-05-07T14:12:06Zoai:ojs.emnuvens.com.br:article/1Revistahttps://escsresidencias.emnuvens.com.br/hrjPUBhttps://escsresidencias.emnuvens.com.br/hrj/oaihrj@escs.edu.br || vanessacampos@escs.edu.br2675-29132675-2913opendoar:2023-01-12T16:39:05.976533Health Residencies Journal (HRJ) - Escola Superior de Ciências da Saúde (ESCS)false |
dc.title.none.fl_str_mv |
Malignant peripheral nerve sheath tumor - a case report and review |
title |
Malignant peripheral nerve sheath tumor - a case report and review |
spellingShingle |
Malignant peripheral nerve sheath tumor - a case report and review Rabelo Gonzalez Veldman, Danielle Malignant peripheral nerve sheath tumor staging Ki67 s100 |
title_short |
Malignant peripheral nerve sheath tumor - a case report and review |
title_full |
Malignant peripheral nerve sheath tumor - a case report and review |
title_fullStr |
Malignant peripheral nerve sheath tumor - a case report and review |
title_full_unstemmed |
Malignant peripheral nerve sheath tumor - a case report and review |
title_sort |
Malignant peripheral nerve sheath tumor - a case report and review |
author |
Rabelo Gonzalez Veldman, Danielle |
author_facet |
Rabelo Gonzalez Veldman, Danielle Batista da Mota, Fernando Henrique Ribeiro Vieira, Laís Carrijo dos Santo, Igor Diego Araújo Marques, Anna Carolina Roma Rodrigues, Alessandra Monteiro da Silva Veldman, Pieter |
author_role |
author |
author2 |
Batista da Mota, Fernando Henrique Ribeiro Vieira, Laís Carrijo dos Santo, Igor Diego Araújo Marques, Anna Carolina Roma Rodrigues, Alessandra Monteiro da Silva Veldman, Pieter |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Rabelo Gonzalez Veldman, Danielle Batista da Mota, Fernando Henrique Ribeiro Vieira, Laís Carrijo dos Santo, Igor Diego Araújo Marques, Anna Carolina Roma Rodrigues, Alessandra Monteiro da Silva Veldman, Pieter |
dc.subject.por.fl_str_mv |
Malignant peripheral nerve sheath tumor staging Ki67 s100 |
topic |
Malignant peripheral nerve sheath tumor staging Ki67 s100 |
description |
This case report aims to contribute to the understanding and to present a new look on the treatment of a rare, aggressive and poorly understood pathology, known as malignant tumor of the peripheral nerve myelin sheath. The objective of this research is to help building a better understanding of this pathology and to evaluate what is new in diagnosis and treatment. We used PubMed’s articles with the descriptors: malignant peripheral nerve sheath tumor, Ki67, and malignant tumor immunohistochemistry of the peripheral nerve sheath. 17 articles were selected. We also used the descriptor “sarcoma staging” for the visualization of a book chapter and a journal. Malignant neoplasm of the peripheral nerve myelin sheath is a disease that mainly affects neurofibromatosis-1 or patients with prior radiotherapy, but may occur randomly, as with the patient in question. Due to illness multiple incidence locations, the symptoms may be late and staging is difficult. The staging is performed taking into account the size of the primary tumor, its location, lymph node involvement, presence of distant metastases and degree of cell differentiation. The diagnosis is made after resection of the piece with anatomopathological and immunohistochemical analysis, which may delay the treatment. Therefore, it has been seen that the most common treatment continues to be complete surgery with free margins, but there are promising studies in the genetics field for the treatment and better understanding of this pathology |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-05-16 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://escsresidencias.emnuvens.com.br/hrj/article/view/1 10.51723/hrj.v1i3.1 |
url |
https://escsresidencias.emnuvens.com.br/hrj/article/view/1 |
identifier_str_mv |
10.51723/hrj.v1i3.1 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://escsresidencias.emnuvens.com.br/hrj/article/view/1/24 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2020 Health Residencies Journal - HRJ info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2020 Health Residencies Journal - HRJ |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Coordenação de Pós-Graduação lato sensu e Extensão da Escola Superior de Ciências da Saúde |
publisher.none.fl_str_mv |
Coordenação de Pós-Graduação lato sensu e Extensão da Escola Superior de Ciências da Saúde |
dc.source.none.fl_str_mv |
Health Residencies Journal - HRJ; v. 1 n. 3 (2020): Desafios em tempo de Pandemia; 16-27 2675-2913 reponame:Health Residencies Journal (HRJ) instname:Escola Superior de Ciências da Saúde (ESCS) instacron:ESCS |
instname_str |
Escola Superior de Ciências da Saúde (ESCS) |
instacron_str |
ESCS |
institution |
ESCS |
reponame_str |
Health Residencies Journal (HRJ) |
collection |
Health Residencies Journal (HRJ) |
repository.name.fl_str_mv |
Health Residencies Journal (HRJ) - Escola Superior de Ciências da Saúde (ESCS) |
repository.mail.fl_str_mv |
hrj@escs.edu.br || vanessacampos@escs.edu.br |
_version_ |
1797051240299888640 |